A synthetic peptide duo that may help signal skin to look firmer and smoother, but research is still early and results vary.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic peptide duo that may help signal skin to look firmer and smoother, but research is still early and results vary.
Irritation
low
Source
synthetic
SH-Polypeptide-57 is a lab-made peptide that may help support collagen and make skin look firmer, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-58 is a synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but results vary and it works best in a consistent routine.
Irritation
low
Source
synthetic
A popular peptide that mimics the effects of Botox by temporarily relaxing facial muscles to soften expression lines.
Irritation
low
Source
synthetic
SH-Polypeptide-60 is a lab-made peptide that may help support collagen and reduce fine lines, but long-term human data is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-62 is a lab-made peptide that may help support collagen and elastin for a firmer, smoother look, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and support firmer-looking skin, but human studies are limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and reduce fine lines, but human research is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-67 is a lab-made peptide that may help reduce fine lines and support skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
SH-Polypeptide-69 is a lab-made peptide that may help signal skin to produce more collagen, but research is still early and results vary.
Irritation
low
Source
synthetic
A duo of synthetic peptides that signal skin to boost collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-70 is a lab-made peptide that may help firm skin and soften lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-72 is a lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-74 is a lab-made peptide that may help reduce the look of fine lines by signaling skin cells to act younger, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-75 is a lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to look firmer and smoother, with low irritation risk and moderate research support.
Irritation
low
Source
synthetic
SH-Polypeptide-77 is a lab-made peptide that may help reduce fine lines by encouraging your skin to produce more collagen, but results vary and it works best with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-78 is a synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-80 is a lab-made peptide that may help support firmer-looking skin, but research is still emerging.
Irritation
low
Source
synthetic
A promising synthetic peptide that may help firm skin and reduce fine lines, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and improve skin firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften wrinkles, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-86 is a synthetic peptide that may help reduce fine lines by signaling skin cells to produce more collagen, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-89 is a lab-made peptide that may help improve skin firmness and hydration, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-90 is a soy-derived peptide that may help firm and smooth skin by supporting collagen production, but more human studies are needed to confirm its effects.
Irritation
low
Source
semi-synthetic
SH-Polypeptide-91 is a lab-made peptide that may help reduce fine lines by signaling skin cells to produce more collagen, though human studies are limited.
Irritation
low
Source
synthetic
SH-Polypeptide-92 is a lab-made peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
SH-Polypeptide-97 is a lab-made peptide that may help reduce fine lines by encouraging the skin to produce more collagen, though research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and support firmer-looking skin, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
A synthetic peptide duo that may help soften fine lines and support firmer-looking skin, though long-term human data is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-99 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness with low irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften expression lines, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften fine lines, but human studies are still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin by signaling collagen production, but human studies are limited.
Irritation
low
Source
synthetic
A gentle, antioxidant-rich mushroom powder that may help calm skin and fight free radicals, though research is still emerging.
Irritation
low
Source
natural
Shark liver oil is a rich source of squalene, a natural emollient that hydrates and protects skin, but ethical and sustainability concerns have led many brands to switch to plant-based alternatives.
Irritation
low
Source
natural
A gentle plant extract with antioxidant potential, but research is still early and benefits are not yet proven in human skin.
Irritation
low
Source
natural
A deeply nourishing, non-irritating butter that softens and protects the skin without clogging pores.
Irritation
low
Source
natural
A gentle, non-greasy emollient that helps soften skin and improve the feel of creams and balms.
Irritation
low
Source
semi-synthetic
A lightweight, non-greasy emollient that delivers shea butter's moisturizing benefits without the heavy feel, suitable for most skin types.
Irritation
low
Source
semi-synthetic
A silky, non-greasy emollient derived from shea butter that moisturizes without the heavy feel of traditional shea butter.
Irritation
low
Source
semi-synthetic
A nourishing extract from shea butter that hydrates and softens skin without feeling overly greasy.
Irritation
low
Source
natural
A modified shea butter that spreads easily and hydrates without greasiness, suitable for most skin types.
Irritation
low
Source
semi-synthetic
A gentle, non-greasy emollient derived from shea butter that softens skin and helps maintain moisture without clogging pores.
Irritation
low
Source
natural
A gentle, non-greasy emollient that improves skin softness without clogging pores, ideal for dry or sensitive skin.
Irritation
low
Source
semi-synthetic
A gentle silicone-enhanced emollient that softens skin without greasiness, but its PEG and silicone content may not suit everyone.
Irritation
low
Source
semi-synthetic
A gentle, water-friendly derivative of shea butter that helps blend oil and water in formulas without the greasiness of plain shea butter.
Irritation
low
Source
semi-synthetic
A water-friendly version of shea butter that hydrates and helps blend oils and water in your products, with a lighter feel than traditional shea butter.
Irritation
low
Source
semi-synthetic
A mild, plant-based emulsifier that helps blend oil and water while leaving skin feeling soft and smooth.
Irritation
low
Source
semi-synthetic
A mild, eco-friendly emulsifier that helps blend oil and water while leaving skin feeling soft and smooth.
Irritation
low
Source
semi-synthetic
A mild, eco-friendly emulsifier that helps blend oil and water in creams and lotions while leaving skin feeling soft.
Irritation
low
Source
semi-synthetic
A powerhouse fraction of shea butter that soothes, repairs, and strengthens the skin barrier without the heavy, greasy feel of whole shea butter.
Irritation
low
Source
natural