A synthetic fatty acid with emerging antimicrobial potential, but limited research on long-term skin benefits.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
0
Reviewed ingredients
0
Low-concern standouts
0
Need usage caution
A synthetic fatty acid with emerging antimicrobial potential, but limited research on long-term skin benefits.
Irritation
low
Source
synthetic
4-Terpineol is a key active in tea tree oil that helps fight acne-causing bacteria and calm redness, but it can be irritating at high concentrations.
Irritation
moderate
Source
natural
Abietic acid is a pine-derived compound with promising anti-acne and anti-inflammatory benefits, but it may cause irritation or clog pores in sensitive skin.
Irritation
moderate
Source
natural
Alcloxa is an old-school antimicrobial that helps control odor but can be irritating for sensitive skin.
Irritation
moderate
Source
synthetic
Cajaputi extract offers antimicrobial benefits similar to tea tree oil, but can be irritating for sensitive skin.
Irritation
moderate
Source
natural
Carpronium chloride is a synthetic ingredient that helps control microbes and condition skin or hair, but it may cause irritation for sensitive individuals.
Irritation
moderate
Source
synthetic
Carvacrol is a potent plant-derived antimicrobial that can help fight acne-causing bacteria, but it may irritate sensitive skin at higher concentrations.
Irritation
moderate
Source
natural
Cetylpyridinium chloride is an effective antimicrobial that helps reduce plaque and gingivitis in oral care, but it can be irritating for sensitive skin or mucous membranes.
Irritation
moderate
Source
synthetic
Chlorhexidine dihydrochloride is a potent antimicrobial that can help control bacteria on skin, but it may cause irritation in sensitive individuals and is not a standard skincare ingredient for daily use.
Irritation
moderate
Source
synthetic
Cineole can offer a cooling, refreshing feel and some antimicrobial benefits, but it may irritate sensitive skin, especially at higher concentrations.
Irritation
moderate
Source
natural
Cloflucarban is an effective antimicrobial but has raised safety concerns similar to triclosan, leading to restricted use in some regions.
Irritation
moderate
Source
synthetic
Clove oil can help fight acne-causing bacteria, but it is very potent and can easily irritate or burn skin if used undiluted.
Irritation
high
Source
natural
Copper sulfate is a trace mineral salt that may help with acne and skin repair, but it can be irritating at higher concentrations and is not a must-have ingredient.
Irritation
moderate
Source
synthetic
Copper Usnate is a lichen-derived ingredient with antimicrobial and antioxidant potential, but its use in skincare is limited by moderate irritation risk and emerging research.
Irritation
moderate
Source
natural
Cuprous oxide offers antimicrobial benefits but may cause irritation in sensitive skin; it's not a common everyday ingredient.
Irritation
moderate
Source
natural
Diallyl sulfide is a natural sulfur compound with antimicrobial potential, but its strong odor and limited skincare research make it a niche ingredient.
Irritation
moderate
Source
natural
Flavesone is a natural antimicrobial compound from tea tree relatives, showing promise for acne-prone skin, but research is still early and it may cause irritation at higher concentrations.
Irritation
moderate
Source
natural
Gallium maltolate is an experimental ingredient with promising antimicrobial and anti-inflammatory properties, but it is not yet widely used or proven safe in everyday skincare.
Irritation
moderate
Source
synthetic
Hexetidine is an antiseptic that can help reduce bacteria on skin and in the mouth, but it may cause irritation for sensitive users.
Irritation
moderate
Source
synthetic
Hydrogen peroxide can kill bacteria and lighten skin, but it's harsh and can damage healthy skin cells, making it a risky choice for routine skincare.
Irritation
moderate
Source
synthetic
A gentle, non-irritating antimicrobial that helps calm redness and support skin healing without drying or stinging.
Irritation
low
Source
synthetic
Isoborneol offers a cooling sensation and mild antimicrobial benefits, but may cause irritation in sensitive skin at higher concentrations.
Irritation
moderate
Source
natural
Isoleptospermone is a plant-derived compound with promising antimicrobial activity, but research in cosmetic applications is still limited.
Irritation
low
Source
natural
A synthetic berberine derivative with antimicrobial potential, but limited human safety data and a moderate irritation risk.
Irritation
moderate
Source
synthetic
Lactoferricin is a milk-derived peptide that may help calm skin and reduce unwanted bacteria, but research is still early.
Irritation
low
Source
natural
Leptospermone is a natural compound from tea tree relatives that helps fight acne-causing bacteria while being gentle on skin.
Irritation
low
Source
natural
Lippia origanoides oil offers antioxidant and antimicrobial benefits, but its strong fragrance and potential for irritation mean it's best used in low concentrations and not for sensitive skin.
Irritation
moderate
Source
natural
Manuka oil is a natural antimicrobial ingredient that can help calm blemishes, but it must be used at low concentrations to avoid skin irritation.
Irritation
moderate
Source
natural
A potent antimicrobial from wasabi that may help with acne and inflammation, but its strong nature requires careful formulation.
Irritation
moderate
Source
natural
Nisin is a gentle, naturally derived preservative that helps keep skincare products fresh while supporting a healthy skin microbiome.
Irritation
low
Source
natural
Octenidine HCl is a potent antimicrobial used in medical antiseptics, not a typical skincare ingredient; it may be too harsh for daily cosmetic use.
Irritation
moderate
Source
synthetic
Oregano leaf oil is a strong antimicrobial essential oil that can help with acne but is highly irritating and should be used only in very low concentrations.
Irritation
high
Source
natural
Ozone is a powerful gas with antimicrobial potential, but its use in skincare is experimental and carries significant safety concerns due to its reactivity and instability.
Irritation
high
Source
synthetic
Ozonized turpentine is a niche ingredient with potential antimicrobial benefits, but its strong odor and irritation risk limit its appeal for everyday skincare.
Irritation
moderate
Source
semi-synthetic
Phenethyl Crotonate is a gentle synthetic ingredient that may help control bacteria on skin, but research is limited and it's not a standalone acne solution.
Irritation
low
Source
synthetic
A stabilized hydrogen peroxide that can help with acne and brightening, but may cause irritation in sensitive skin.
Irritation
moderate
Source
semi-synthetic
Quinine can help calm inflammation and fight microbes, but it may irritate sensitive skin and is not a proven anti-aging ingredient.
Irritation
moderate
Source
natural
Sclareol is a natural compound from clary sage that may help calm skin and fight acne-causing bacteria, but research is still emerging.
Irritation
low
Source
natural
Silver acetylmethionate is an antimicrobial ingredient that helps control odor-causing bacteria, but it may cause irritation in sensitive skin.
Irritation
moderate
Source
synthetic
Silver lactate is an effective antimicrobial ingredient often used in deodorants, but it may cause irritation in sensitive skin and has limited long-term safety data in leave-on products.
Irritation
moderate
Source
synthetic
Silver salicylate offers a unique blend of antibacterial action and gentle exfoliation, but may cause irritation for sensitive skin and has limited long-term safety data.
Irritation
moderate
Source
semi-synthetic
Silver titanium carbide is an experimental ingredient with potential antimicrobial benefits, but its safety and efficacy in cosmetics are not well established.
Irritation
moderate
Source
synthetic
A gentle, plant-derived antimicrobial that helps control acne-causing bacteria and support clear skin without harsh side effects.
Irritation
low
Source
natural
Sodium hypochlorite is a potent disinfectant used in tiny amounts for acne and skin cleansing, but it can be irritating and drying at higher concentrations.
Irritation
high
Source
synthetic
Sodium Usnate is a lichen-derived antimicrobial that can help control odor and surface bacteria, but it may cause irritation in sensitive skin at higher concentrations.
Irritation
moderate
Source
natural
A sulfur-infused oil derivative that helps control acne and dandruff by reducing microbes and excess oil, but may cause irritation in sensitive skin.
Irritation
moderate
Source
semi-synthetic
A natural antimicrobial extract that can help with acne-prone skin but may cause irritation at high concentrations.
Irritation
moderate
Source
natural
A gentle fatty acid that helps control acne-causing bacteria and fungi without harsh side effects.
Irritation
low
Source
natural
Undecylenic acid is a gentle antifungal and antimicrobial ingredient that can help manage acne and dandruff, but may cause irritation in sensitive skin at higher concentrations.
Irritation
moderate
Source
natural
A mild, plant-based ingredient that fights odor-causing bacteria while being kind to sensitive skin.
Irritation
low
Source
natural
A gentle, castor-oil-derived alcohol that helps control odor-causing bacteria and fungi without drying out the skin.
Irritation
low
Source
natural
Usnea Filipendula Extract is a natural lichen extract with promising antimicrobial activity, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
Usnic acid is a lichen-derived compound with antimicrobial and antioxidant benefits, but it can be irritating at high concentrations and is not well-studied in long-term skincare use.
Irritation
moderate
Source
natural
Zinc peroxide offers mild antimicrobial and drying benefits for acne-prone skin, but it can be irritating and is less common than alternatives like benzoyl peroxide.
Irritation
moderate
Source
synthetic
Zinc pyrithione is a well-studied antimicrobial that helps control dandruff and scalp flaking, but it may cause mild irritation for sensitive skin.
Irritation
low
Source
synthetic
Zinc Salicylate combines zinc's soothing properties with salicylic acid's exfoliating action, but it can be irritating for sensitive skin.
Irritation
moderate
Source
synthetic
Zinc Thiosalicylate is a synthetic zinc compound that may help control dandruff and surface bacteria, but research is limited and it can be irritating for sensitive skin.
Irritation
moderate
Source
synthetic