A gentle, naturally derived fatty acid that helps calm and condition the skin, with emerging research supporting its soothing benefits.
Irritation
low
Source
natural
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A gentle, naturally derived fatty acid that helps calm and condition the skin, with emerging research supporting its soothing benefits.
Irritation
low
Source
natural
A gentle plant extract with antioxidant and soothing potential, but research is still early and benefits are not yet proven in large human studies.
Irritation
low
Source
natural
A gentle, synthetic ingredient that helps calm redness and sensitivity while supporting a more even skin tone.
Irritation
low
Source
synthetic
Soothing Agent
ACETYL METHYL HYDROXYPROLINATYL GLYCYRRHETINATE
A gentle, licorice-derived ingredient that helps calm redness and irritation without the strong smell or stickiness of raw licorice extract.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived compound that helps calm redness and supports the skin's natural repair process.
Irritation
low
Source
semi-synthetic
Soothing agent
Adamantanylcarboxamido Trifluoromethylbenzonitrile
A synthetic compound that may reduce skin sensitivity by calming nerve signals, but research is still early.
Irritation
low
Source
synthetic
Agave leaf extract is a gentle, plant-based ingredient that may help soothe and hydrate the skin, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
Agave Rigida Extract is a gentle, plant-derived ingredient that helps soothe and hydrate the skin, making it a good choice for sensitive or irritated skin types.
Irritation
low
Source
natural
A gentle, biotech-derived ingredient that may help calm skin and support a healthy microbiome, but research is still early.
Irritation
low
Source
biotech
Aldioxa is a gentle, soothing ingredient that helps calm irritated skin and reduce minor redness, but it is not a powerhouse active.
Irritation
low
Source
semi-synthetic
A gentle red algae extract that may help calm and hydrate the skin, though research is still emerging.
Irritation
low
Source
natural
A gentle, plant-derived soother that helps calm irritated skin and supports a healthy-looking complexion.
Irritation
low
Source
natural
A gentle, dual-action ingredient that calms irritation and supports skin repair, ideal for sensitive or stressed skin.
Irritation
low
Source
semi-synthetic
A gentle, dual-action ingredient that soothes irritation and helps skin hold onto moisture, ideal for sensitive or compromised skin.
Irritation
low
Source
semi-synthetic
A gentle, dual-action ingredient that soothes irritation and supports skin repair without clogging pores.
Irritation
low
Source
semi-synthetic
Allantoin PABA combines soothing allantoin with PABA, a former sunscreen ingredient, but PABA is rarely used today due to safety concerns and allergy risks.
Irritation
low
Source
semi-synthetic
A gentle, well-tolerated combination that soothes irritation and supports moisture retention, ideal for sensitive or compromised skin.
Irritation
low
Source
semi-synthetic
A gentle, probiotic-fermented aloe ingredient that soothes and conditions skin without irritation.
Irritation
low
Source
biotech
A soothing, hydrating botanical extract with antioxidant benefits, generally safe and well-tolerated for most skin types.
Irritation
low
Source
natural
A gentle, plant-derived powder that helps calm and hydrate skin, but is less studied than its cousin Aloe barbadensis (common aloe vera).
Irritation
low
Source
natural
Aloe Maculata Leaf Extract is a gentle, soothing botanical that helps calm irritated skin and provides light hydration, but it is less researched than classic Aloe vera.
Irritation
low
Source
natural
Aloe resin is a natural, soothing ingredient that may help calm irritated skin, but research on its specific benefits is still emerging.
Irritation
low
Source
natural
A gentle, water-soluble powder that soothes and hydrates skin, ideal for sensitive or irritated complexions.
Irritation
low
Source
natural
A gentle, plant-based powder that soothes and hydrates skin, but its benefits depend heavily on processing and formulation.
Irritation
low
Source
natural
Alpha-santalol is the primary fragrant component of sandalwood oil, offering a subtle woody scent and potential soothing benefits, but it must be used at low concentrations to minimize the risk of skin irritation.
Irritation
low
Source
natural
A gentle, plant-derived hydrosol that may help calm skin and provide mild antioxidant benefits, but research is limited.
Irritation
low
Source
natural
A gentle, licorice-derived ingredient that helps calm irritated skin and reduce redness without harsh side effects.
Irritation
low
Source
natural
A fermented botanical extract that soothes and protects skin with antioxidants, ideal for sensitive or stressed skin.
Irritation
low
Source
biotech
A traditional plant extract with potential soothing benefits, but research is limited and it's not a mainstream ingredient.
Irritation
low
Source
natural
A gentle alpine plant extract that may help calm irritated skin and provide antioxidant protection, though research is still emerging.
Irritation
low
Source
natural
A fermented botanical extract that may offer soothing and conditioning benefits, but research is still emerging.
Irritation
low
Source
biotech
Annual feverfew oil is a gentle, plant-based oil that helps calm redness and irritation, making it a good choice for sensitive skin.
Irritation
low
Source
natural
A gentle, fragrant oil from the feverfew family that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
A gentle, antioxidant-rich Arctic plant extract that may help calm irritated skin, but research is still early.
Irritation
low
Source
natural
Arnica flower oil can help calm irritated skin, but it must be used in low concentrations and never on broken skin due to potential irritation.
Irritation
moderate
Source
natural
A gentle, plant-based ingredient that may help calm redness and protect skin from environmental stress, though human studies are still limited.
Irritation
low
Source
natural
A gentle, plant-based extract that may help calm irritated skin and provide antioxidant protection, though research specific to this species is still limited.
Irritation
low
Source
natural
A gentle, hydrating botanical water that may help calm redness and provide antioxidant protection, especially popular in Korean skincare.
Irritation
low
Source
natural
A gentle, antioxidant-rich botanical extract that helps calm irritated skin and supports a healthy-looking complexion.
Irritation
low
Source
natural
A gentle, aromatic oil from Korean mugwort that may help calm irritated skin and provide antioxidant support.
Irritation
low
Source
natural
A gentle, plant-based ingredient that may help calm redness and protect skin from environmental stress, though research is still early.
Irritation
low
Source
natural
A gentle, water-based botanical extract with potential soothing and antioxidant benefits, but research is limited.
Irritation
low
Source
natural
A gentle seaweed powder that hydrates, soothes, and provides antioxidant protection, ideal for sensitive or dry skin.
Irritation
low
Source
natural
Asiaticoside is a soothing, skin-repairing compound from Gotu Kola that helps calm irritation and supports a healthy skin barrier.
Irritation
low
Source
natural
A gentle seaweed extract that may help calm irritated skin and provide antioxidant protection, though research is still emerging.
Irritation
low
Source
natural
A gentle, fermented ingredient that helps calm and condition the skin, especially beneficial for sensitive or irritated complexions.
Irritation
low
Source
biotech
A gentle, fermented ingredient that may help calm skin and support hydration, though research on its benefits is still emerging.
Irritation
low
Source
biotech
A gentle botanical extract that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
Soothing agent
LACTOBACILLUS/ASTRAGALUS MEMBRANACEUS ROOT EXTRACT FERMENT FILTRATE
A gentle fermented botanical that may help calm skin and support a healthy barrier, but research is still early.
Irritation
low
Source
biotech
A gentle, plant-based extract that may help calm irritated skin and provide light hydration, though research is still emerging.
Irritation
low
Source
natural
A gentle herbal oil with traditional roots, offering soothing and antioxidant benefits, though modern research is still limited.
Irritation
low
Source
natural
A gentle, plant-based extract that may help calm and hydrate skin, though research is still emerging.
Irritation
low
Source
natural
Azelamide MEA is a milder, less irritating cousin of azelaic acid that helps calm redness and support a clearer complexion without the typical itch or sting.
Irritation
low
Source
semi-synthetic
Azulene is a gentle, blue-hued ingredient that helps calm redness and irritation, making it a favorite for sensitive skin.
Irritation
low
Source
natural
A gentle, plant-based extract that helps calm irritation and provides antioxidant protection, ideal for sensitive or reactive skin.
Irritation
low
Source
natural
A gentle plant extract that may help calm irritated skin and provide antioxidant support, though research is still early.
Irritation
low
Source
natural
Baccharis Oil is a gentle, plant-based oil with antioxidant and soothing potential, but research is still early and it may cause irritation in sensitive skin.
Irritation
moderate
Source
natural
A gentle, fermented ingredient that may help calm skin and support a healthy skin barrier, but research is still emerging.
Irritation
low
Source
biotech
Skin Conditioning Agent
Bacillus/Folic Acid Ferment Filtrate Extract
A gentle, biotech-derived ingredient that may help calm and condition the skin, though research is still emerging.
Irritation
low
Source
biotech
A gentle fermented ingredient that may help calm skin and provide antioxidant benefits, though research is still emerging.
Irritation
low
Source
biotech