Ammonium bisulfite is a chemical reducing agent used in professional hair treatments, but it can be irritating and is not common in everyday skincare.
Irritation
moderate
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
Ammonium bisulfite is a chemical reducing agent used in professional hair treatments, but it can be irritating and is not common in everyday skincare.
Irritation
moderate
Source
synthetic
Ammonium Persulfate is an effective hair bleach but can cause severe skin and respiratory irritation; it is not recommended for sensitive individuals or at-home use without precautions.
Irritation
high
Source
synthetic
Ammonium sulfite is an effective reducing agent for hair restructuring but can be irritating and has a strong odor, making it more common in salon treatments than daily-use products.
Irritation
moderate
Source
synthetic
A strong chemical that breaks hair bonds for removal or straightening, but can irritate skin and requires careful use.
Irritation
high
Source
synthetic
A lab-made peptide that encourages hair and nail growth by mimicking natural signaling molecules.
Irritation
low
Source
synthetic
A gentle synthetic film-former that smooths hair and reduces frizz without heavy buildup.
Irritation
low
Source
synthetic
A gentle conditioning ingredient that helps smooth hair and soften skin, but is less common than other cholesterol derivatives.
Irritation
low
Source
semi-synthetic
A synthetic conditioning agent that reduces static and softens hair, but may cause irritation for sensitive scalps.
Irritation
moderate
Source
synthetic
Cysteine is a gentle antioxidant and hair-strengthening amino acid that supports skin's natural defenses and may help with hair texture, but it's not a standalone solution for major skin concerns.
Irritation
low
Source
natural
Cystine is a gentle antioxidant amino acid that may help protect skin from environmental stress and support hair strength, but it is not a standout anti-aging ingredient.
Irritation
low
Source
natural
Hair growth stimulant
DECHLORO CYCLOPROPYLMETHYLCLOPROSTENOLAMIDE
A synthetic prostaglandin analog that may help with hair growth, but evidence is limited and irritation is possible.
Irritation
moderate
Source
synthetic
A gentle amino-acid derivative that helps strengthen hair and support skin firmness without irritation.
Irritation
low
Source
synthetic
Dihydroxyindole is a natural melanin precursor that may help enhance pigmentation and provide antioxidant benefits, but its cosmetic use is still emerging and not widely studied in humans.
Irritation
low
Source
natural
A gentle amino acid derivative that helps reinforce hair structure, making strands feel stronger and less prone to breakage.
Irritation
low
Source
semi-synthetic
A gentle, science-backed ingredient that helps rebuild damaged hair from the inside out by delivering cysteine, a key building block of hair proteins.
Irritation
low
Source
semi-synthetic
A gentle amino-acid derivative that helps condition hair and skin without heavy buildup.
Irritation
low
Source
synthetic
A synthetic film former that helps hold hairstyles and improve product wear, but offers no skin benefit beyond texture.
Irritation
low
Source
synthetic
Antistatic Agent
Dipalmitoylethyl Hydroxyethylmonium Methosulfate
A mild, synthetic conditioning agent that helps reduce static and improve hair manageability without heavy buildup.
Irritation
low
Source
synthetic
Film Former
DITHIODIETHYL BIS-DIHYDROXYDIMETHYLBUTYRAMIDE
A synthetic ingredient that may help strengthen hair and skin by forming disulfide bonds, but research is still limited.
Irritation
low
Source
synthetic
A synthetic bond-builder that helps strengthen damaged hair by reforming disulfide bridges inside the hair fiber.
Irritation
low
Source
synthetic
A strong chemical that breaks hair bonds for removal or reshaping, but can irritate skin if not used carefully.
Irritation
moderate
Source
synthetic
Ethyl Biotinate is a more absorbable form of biotin that may help strengthen hair and nails when applied topically, but its effects are modest and not a substitute for internal nutrition.
Irritation
low
Source
semi-synthetic
Ethyl Cysteinate HCl is an effective hair-softening ingredient in depilatory and straightening products, but it can be irritating and should be used with caution.
Irritation
moderate
Source
synthetic
Ethylene carbonate is a synthetic solvent that helps products spread and dry, but it can be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
A strong chemical reducing agent used in professional hair straightening and color removal, but it can be irritating and is not recommended for regular at-home use.
Irritation
high
Source
synthetic
HC Blue No. 11 is a synthetic hair dye that can provide vibrant blue color, but it may cause skin irritation or allergic reactions in sensitive individuals.
Irritation
moderate
Source
synthetic
HC Blue No. 18 is a synthetic hair dye that adds blue tones to semi-permanent formulas; it is generally considered safe for external use but may cause mild irritation in sensitive individuals.
Irritation
low
Source
synthetic
HC Blue No. 2 is a synthetic hair dye that delivers blue color but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
HC Red No. 17 is a synthetic hair dye that adds red tones but may cause scalp irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
HC Violet No. 1 is a synthetic dye that adds violet tones to hair, commonly used to neutralize brassiness or create cool shades, but it may cause mild irritation in sensitive individuals.
Irritation
low
Source
synthetic
HC Yellow No. 13 is a synthetic colorant used in hair dyes, generally considered safe in rinse-off products but may cause irritation for sensitive scalps.
Irritation
moderate
Source
synthetic
HC Yellow No. 15 is a synthetic yellow dye for hair color, generally considered safe in rinse-off products but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
HC Yellow No. 16 is a synthetic colorant used in hair dyes, generally considered safe in regulated concentrations but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A gentle, modified keratin that helps strengthen hair and reduce frizz without the harshness of some other protein treatments.
Irritation
low
Source
semi-synthetic
A synthetic hair conditioning agent that helps detangle and soften hair without heavy buildup, but has limited research on long-term effects.
Irritation
low
Source
synthetic
Antistatic agent
LAURDIMONIUM HYDROXYPROPYL HYDROLYZED WHEAT STARCH
A gentle, plant-derived conditioning ingredient that helps reduce frizz and static without heavy buildup.
Irritation
low
Source
semi-synthetic
A synthetic conditioning agent that helps soften hair and reduce static, but may cause irritation for sensitive scalps.
Irritation
moderate
Source
synthetic
A synthetic ingredient that helps nail and hair products stick better and last longer, but may cause irritation for sensitive users.
Irritation
moderate
Source
synthetic
A synthetic ingredient that helps nail polish and hair products stick better and last longer, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic ingredient that helps nail and hair products stick better and last longer, but with limited safety data.
Irritation
moderate
Source
synthetic
An experimental hybrid that aims to combine minoxidil's hair-growth effects with hyaluronic acid's moisture, but clinical data on the combined molecule is very limited.
Irritation
moderate
Source
semi-synthetic
A newer minoxidil variant that may offer better scalp tolerance, but research is still limited compared to standard minoxidil.
Irritation
moderate
Source
synthetic
A lab-made peptide that borrows minoxidil's hair-signaling concept, but with far less evidence and no drug status.
Irritation
low
Source
synthetic
A novel peptide that aims to support hair growth with less irritation than traditional minoxidil, but clinical evidence is still limited.
Irritation
low
Source
synthetic
A synthetic hair conditioner that helps detangle and soften hair, but has limited published safety data.
Irritation
low
Source
synthetic
A synthetic conditioning agent that reduces static and softens hair, but may cause irritation for sensitive scalps.
Irritation
moderate
Source
synthetic
A synthetic crosslinker that strengthens nail and hair formulas, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Film Former
PHTHALIC ANHYDRIDE/BENZOIC ACID/TRIMETHYLOLPROPANE COPOLYMER
A synthetic film former that gives nail polish and hair products a tough, glossy finish, but its long-term safety data is limited.
Irritation
low
Source
synthetic
Polyoxymethylene melamine is a synthetic film former found mainly in nail and hair products, not a typical skincare ingredient, and has limited safety data.
Irritation
low
Source
synthetic
A gentle synthetic polymer that smooths hair and reduces static without heavy buildup.
Irritation
low
Source
synthetic
Polyquaternium-84 is a gentle, synthetic conditioning polymer that smooths hair and reduces static without heavy buildup.
Irritation
low
Source
synthetic
Polyquaternium-86 is a gentle conditioning polymer that helps detangle hair and reduce frizz without heavy buildup.
Irritation
low
Source
synthetic
Potassium Persulfate is a strong oxidizer used in hair bleach; it can cause skin and eye irritation and is not suitable for everyday skincare.
Irritation
high
Source
synthetic
Hair growth stimulant
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE OXOTHIAZOLIDINECARBOXYLATE
A synthetic molecule that may help reduce hair thinning by supporting hair follicle activity, but research is still limited.
Irritation
low
Source
synthetic
Quaternium-43 is a synthetic conditioning ingredient that helps reduce static and improve hair manageability, but it may not suit very sensitive scalps.
Irritation
low
Source
synthetic
Quaternium-82 is a synthetic conditioning ingredient that helps reduce static and improve hair feel, but it may build up on fine or low-porosity hair over time.
Irritation
low
Source
synthetic
A synthetic conditioning ingredient that helps reduce flyaways and static in hair, generally considered safe for most users.
Irritation
low
Source
synthetic
Quaternium-95 is a synthetic conditioning ingredient that helps detangle and soften hair with a low risk of irritation.
Irritation
low
Source
synthetic
A synthetic conditioning agent that reduces static and softens hair, but may not suit those avoiding ethoxylated ingredients.
Irritation
low
Source
synthetic
Antistatic Agent
STEARDIMONIUM HYDROXYPROPYL HYDROLYZED JOJOBA PROTEIN
A gentle, protein-based conditioning ingredient that helps reduce frizz and static without heavy buildup.
Irritation
low
Source
semi-synthetic