Ammonium fluoride is effective for cavity prevention in toothpaste but is not used in leave-on skincare due to irritation concerns.
Irritation
moderate
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
Ammonium fluoride is effective for cavity prevention in toothpaste but is not used in leave-on skincare due to irritation concerns.
Irritation
moderate
Source
synthetic
Ammonium fluorosilicate is a fluoride source used in oral care for cavity prevention, but it is not a typical skincare ingredient and can be toxic if ingested in large amounts.
Irritation
moderate
Source
synthetic
A well-studied fluoride compound that helps strengthen tooth enamel and reduce cavity risk when used in oral care products.
Irritation
low
Source
synthetic
Calcium fluoride is a mineral abrasive found mainly in toothpaste; it is not a typical skincare ingredient and may cause irritation if inhaled or used in high concentrations on skin.
Irritation
moderate
Source
natural
A gentle mineral salt that helps balance pH and may support skin barrier health, most commonly used in oral care for enamel protection.
Irritation
low
Source
synthetic
Calcium peroxide is a bleaching agent mainly used in oral care products; it can whiten teeth but may cause gum irritation if overused.
Irritation
moderate
Source
synthetic
A gentle mineral abrasive that helps polish teeth and exfoliate skin without harshness.
Irritation
low
Source
natural
A fluoride compound that helps prevent cavities and reduce tooth sensitivity, commonly used in toothpaste and mouthwash.
Irritation
low
Source
synthetic
Delmopinol HCl is a synthetic surfactant used in oral care to disrupt plaque formation, but it may cause temporary taste disturbances or mild irritation.
Irritation
moderate
Source
synthetic
Dicalcium phosphate is a gentle, non-irritating abrasive commonly used in toothpaste and some skincare powders to help polish and clean without harshness.
Irritation
low
Source
natural
Neotame is a high-intensity artificial sweetener used to improve taste in oral care and lip products, but it has no skincare benefits and is not a typical cosmetic active ingredient.
Irritation
low
Source
synthetic
A synthetic fluoride compound used in toothpaste to strengthen enamel and prevent cavities, but not typically found in skincare.
Irritation
low
Source
synthetic
Olaflur is a well-studied fluoride ingredient that helps prevent tooth decay by strengthening enamel and reducing acid damage.
Irritation
low
Source
synthetic
A synthetic fluoride compound used in oral care to help prevent cavities, but it may cause irritation in sensitive mouths.
Irritation
moderate
Source
synthetic
Potassium fluorosilicate is a fluoride salt used in oral care for cavity prevention, but it is toxic if ingested in large amounts and requires careful formulation.
Irritation
moderate
Source
synthetic
Potassium nitrate is a well-studied ingredient for reducing tooth sensitivity, but it is not typically used in skincare.
Irritation
low
Source
natural
A gentle mineral abrasive often found in toothpaste and exfoliating products, considered safe and non-irritating for most people.
Irritation
low
Source
synthetic
Sodium fluoride is a proven cavity-fighter in toothpaste and mouthwash, but it is not a skincare ingredient and should not be ingested in large amounts.
Irritation
low
Source
synthetic
Sodium Fluorosilicate is a fluoride source for cavity prevention in toothpaste, but it is not a standard skincare ingredient and can be toxic if ingested in large amounts.
Irritation
moderate
Source
synthetic
A well-studied fluoride compound that effectively prevents cavities when used in toothpaste.
Irritation
low
Source
synthetic
Stannous fluoride is a well-researched anti-cavity ingredient that strengthens enamel and helps reduce tooth sensitivity, but it is not typically used in skincare.
Irritation
low
Source
synthetic
A mineral compound that helps strengthen enamel and reduce sensitivity, but its cosmetic skincare benefits are less established.
Irritation
low
Source
synthetic