A potent depilatory chemical that dissolves hair but can irritate sensitive skin if left on too long.
Irritation
moderate
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A potent depilatory chemical that dissolves hair but can irritate sensitive skin if left on too long.
Irritation
moderate
Source
synthetic
Isopropyl Thioglycolate is an effective depilatory ingredient that dissolves hair, but it can be irritating and has a strong odor, so it's best used with caution and proper formulation.
Irritation
moderate
Source
synthetic
Sodium sulfide is an effective but harsh depilatory that breaks down hair protein; it is not used in leave-on skincare due to high irritation and safety concerns.
Irritation
high
Source
synthetic