A lab-made peptide that mimics natural signals to encourage firmer, smoother-looking skin with minimal irritation.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A lab-made peptide that mimics natural signals to encourage firmer, smoother-looking skin with minimal irritation.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still early.
Irritation
low
Source
synthetic
SH-Pentapeptide-35 is a synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, helping soften fine lines over time with minimal irritation.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce the look of fine lines and support skin firmness with consistent use.
Irritation
low
Source
synthetic
SH-Pentapeptide-40 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
SH-Pentapeptide-5 is a synthetic peptide that may help reduce fine lines by encouraging collagen production, but results are gradual and vary by person.
Irritation
low
Source
synthetic
A synthetic peptide duo that may help firm skin and soften fine lines, but results vary and more human studies are needed.
Irritation
low
Source
synthetic
A well-studied synthetic peptide that helps reduce wrinkles by boosting collagen and calming inflammation, with a strong safety profile.
Irritation
low
Source
synthetic
A synthetic peptide that mimics the action of botulinum toxin to soften expression lines, offering a gentler alternative for wrinkle reduction.
Irritation
low
Source
synthetic
A synthetic peptide blend that may help support collagen production and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen production and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but long-term human data is still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help smooth fine lines and support collagen, but human studies are still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-102 is a synthetic peptide that may help support collagen production for firmer, smoother skin, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and support firmer-looking skin, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
SH-Polypeptide-105 is a lab-made peptide that may help firm skin and reduce fine lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but human data is still limited.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to build more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-11 is a lab-made peptide that may help support collagen production and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-110 is a lab-made peptide that may help support firmer, smoother skin, but research is still early and results vary.
Irritation
low
Source
synthetic
SH-Polypeptide-111 is a synthetic peptide that may help reduce fine lines and support firmer-looking skin, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
SH-Polypeptide-14 is a lab-made peptide that may help reduce fine lines by signaling skin to produce more collagen.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A promising synthetic peptide that may help reduce fine lines and improve skin firmness, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
SH-Polypeptide-18 is a synthetic peptide that mimics the action of botulinum toxin to soften expression lines, offering a non-invasive alternative for wrinkle reduction.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but results vary and long-term data is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to build more collagen, helping reduce fine lines over time.
Irritation
low
Source
synthetic
SH-Polypeptide-28 is a synthetic peptide that may help reduce fine lines and improve skin firmness by signaling collagen production, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-31 is a synthetic peptide that signals skin cells to boost collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-32 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-34 is a lab-made peptide that signals skin to look firmer and more youthful, with a good safety profile for most skin types.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and improve skin firmness, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
SH-Polypeptide-36 is a synthetic peptide that may help reduce fine lines by signaling skin cells to produce more collagen, but human studies are limited.
Irritation
low
Source
synthetic
SH-Polypeptide-37 is a lab-made peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, potentially reducing fine lines over time.
Irritation
low
Source
synthetic
SH-Polypeptide-40 is a lab-made peptide that may help support skin firmness and reduce the look of fine lines, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-41 is a lab-made peptide that may help reduce fine lines by encouraging the skin to produce more collagen, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging and results vary by person.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-45 is a lab-made peptide that may help support firmer-looking skin, but research is still early and results vary.
Irritation
low
Source
synthetic
SH-Polypeptide-46 is a lab-made peptide that signals skin cells to boost collagen, helping smooth wrinkles over time with minimal irritation.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
SH-Polypeptide-49 is a lab-made peptide that may help support skin firmness and smooth fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth fine lines and support skin firmness, but human data is still limited compared to well-studied peptides.
Irritation
low
Source
synthetic
SH-Polypeptide-50 and SH-Polypeptide-56 are synthetic peptides designed to mimic natural signaling molecules that encourage firmer, smoother skin with minimal irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-51 is a lab-made peptide that may help signal skin to produce more collagen, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
SH-Polypeptide-53 is a lab-made peptide that may help reduce fine lines by encouraging the skin to produce more collagen, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-54 is a lab-made peptide that may help support collagen and elastin for firmer, smoother skin, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-55 is a lab-made peptide that may help reduce fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-56 is a lab-made peptide that may help soften expression lines, but research is still early and results vary.
Irritation
low
Source
synthetic