Biotin is a gentle B vitamin that supports skin barrier health and may help hair and nails, but topical benefits are modest compared to oral intake.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
Biotin is a gentle B vitamin that supports skin barrier health and may help hair and nails, but topical benefits are modest compared to oral intake.
Irritation
low
Source
synthetic
Cobamamide is a gentle, active form of vitamin B12 that may help calm redness and support skin repair, but research in topical skincare is still limited.
Irritation
low
Source
biotech
Ergocalciferol (vitamin D2) may support skin health and calm inflammation, but research in topical skincare is still emerging and it is less potent than vitamin D3.
Irritation
low
Source
natural
Folic acid is a gentle B vitamin that may help support skin renewal and barrier health, but research on topical use is still emerging.
Irritation
low
Source
synthetic
Niacin is a well-studied form of vitamin B3 that helps strengthen the skin barrier and even out skin tone, but it can cause temporary flushing in some people.
Irritation
low
Source
synthetic
A gentle, active form of vitamin B6 that helps calm skin and strengthen the moisture barrier without irritation.
Irritation
low
Source
semi-synthetic
Pyridoxine (vitamin B6) is a gentle, water-soluble vitamin that may help regulate oil production and support skin barrier health, though research is still emerging.
Irritation
low
Source
synthetic