3.5
5-Melozol is a synthetic peptide that may help firm and smooth skin, but research is limited and it is not widely studied in peer-reviewed human trials.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient reviewBeauty ingredient research
Beauty ingredients explained in plain English
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
Showing 60 of 539
AllUV absorberUV filterabrasiveabsorbentacne treatmentactiveactive ingredientadhesivealkalizing agentamino acidanti-aginganti-androgenanti-cavityanti-cavity agentanti-inflammatoryanti-irritantanticariesanticavity agentantidandruffantifungalantimicrobialantioxidantantiperspirantantiplaqueastringentbarrier repairbarrier supportbarrier-repairbarrier-supportbinderbinding agentbiotechbiotechnologybond-builderbotanicalbotanical extractbotanical oilbotanical waterbrighteningbrightening agentbufferbuffering agentcell-communicating ingredientceramidechelating agentchemicalchemical intermediateclaycleansercleansingcleansing agentcolorantconditionerconditioningconditioning agentcooling agentcosmeticcosmetic additivecosmetic colorantcosmetic ingredientcosmetic pigmentcosmetic powdercosmetic-texturizercosmetic-waxcosmeticscrosslinking agentdelivery agentdelivery systemdenaturantdeodorantdeodorant agentdepigmenting agentdepilatorydepilatory agentdesensitizing agentdyedye intermediatedye precursordye-intermediateemollientemulsifierenzymeessential oilexfoliantexperimentaleyelashfermentfilm formerfilm-formerfilm-formingfilm-forming agentfirming agentfixativeflavoring agentformulationfragrancefragrance ingredientfunctional ingredientgashair carehair colorhair coloranthair conditionerhair dyehair removalhair-carehair-colorhaircarehumectantindustrialinsecticideintermediatelashlash carelash enhancerlash-and-browlip carelipidmakeupmarine extractmasking agentmicrobiomemicrobiome modulatormineralmoisturizernail carenail-careocclusiveoilopacifieropacifying agentoptical agentoral careotheroxidative dyeoxidative dye precursoroxidizing agentpH adjusterpain reliefpenetration enhancerpeptidepersonal careph adjusterpharmaceuticalpheromonepigmentplant oilplasticizerpolymerpolymer precursorprebioticprescription-drugpreservativepreservative boosterprobioticprocessing agentprocessing aidpropellantproteinpurifyingreducing agentretinoidscalp caresebum regulatorsebum-regulatorself-tannerself-tanningsensory additivesensory agentsensory modifiersiliconeskin barrierskin barrier supportskin conditionerskin conditioningskin conditioning agentskin lighteningskin protectantskin-conditioningskin-conditioning agentskin-identicalskin-identical ingredientskin-lighteningskin-lightening agentskincaresolventsoothingsoothing agentstabilizerstimulantsunscreensurfactantsyntheticsynthetic colorantsynthetic dyesynthetic resinsynthetic-coloranttexture enhancertexturizerthickenertoneruv-absorberuv-filtervasoactivevasodilatorviscosity controlviscosity controllingviscosity controlling agentvitaminwax
4.0
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more independent research is needed.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle amino-acid derivative that may help support skin firmness and resilience, though research is still emerging.
Irritation
low
Source
semi-synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that helps strengthen the skin barrier and soften the look of expression lines over time.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A gentle peptide that helps maintain skin hydration and firmness, but research is still early.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help support skin firmness and reduce fine lines, with low irritation risk.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to but milder than neuropeptides.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical version of neuromodulators.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help soften expression lines and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help soften expression lines and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines and improve skin firmness, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines and support firmer-looking skin with low irritation risk.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help support skin firmness and reduce fine lines, but human studies are limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical version of neuromodulators.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical alternative to injectables.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that temporarily softens expression lines by mimicking the action of a muscle-relaxing protein, offering a gentler alternative to injectables.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that mimics the action of botulinum toxin to soften expression lines, but with a much milder and temporary effect.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that may help soften expression lines over time, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.2
A popular peptide that can soften dynamic wrinkles by relaxing facial muscles, but results are subtle and temporary.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that helps soften expression lines by temporarily relaxing facial muscles, with good safety profile but modest, temporary results.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A cutting-edge synthetic peptide that may help firm skin, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may soften expression lines by mimicking the action of a muscle-relaxing protein, but results are subtle and temporary.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that mimics the action of botulinum toxin to soften expression lines, but with milder, temporary effects.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help improve skin firmness and soften the look of wrinkles with low irritation risk.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help support collagen and reduce fine lines, but human studies are limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A lab-made peptide inspired by carrot proteins that may help smooth wrinkles and firm skin, but human studies are limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient reviewAnti-Wrinkle Agent
Acetyl S-FEA's Viper Pentapeptide-1 Amide
Acetyl S-FEA's Viper Pentapeptide-1 Amide
3.8
A synthetic peptide that mimics snake venom to temporarily relax expression wrinkles, offering a gentle alternative to neurotoxins like Botox.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help soften fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A lab-made peptide that may help firm skin and soften fine lines, but research is still early.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help support collagen and improve skin firmness with low irritation risk.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that may help support skin firmness and reduce fine lines, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A lab-made peptide that may help firm skin and soften lines, but human studies are limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that signals skin cells to support collagen and elastin, helping improve firmness and reduce fine lines.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that helps calm reactive skin and reduce visible redness, making it a smart choice for sensitive skin routines.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that may help firm skin and reduce under-eye bags, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help firm skin and soften fine lines, but research is still emerging.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that may help reduce visible redness and sensitivity over time, but results are subtle and not instant.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that targets under-eye concerns like puffiness and dark circles by supporting collagen and circulation.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle synthetic peptide that may help firm skin and reduce under-eye puffiness, with limited but promising early research.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle peptide that targets under-eye bags and dark circles by supporting circulation and reducing fluid buildup.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A lab-made peptide that encourages collagen production for firmer, smoother skin with a very low risk of irritation.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient reviewAnti-wrinkle agent
Acetyl Trifluoromethylphenyl Valylglycine
Acetyl Trifluoromethylphenyl Valylglycine
3.8
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, but results are subtle and not as strong as injectable treatments.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical alternative to injectables.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder version of neuropeptides.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help support skin firmness and reduce the look of fine lines, but human research is still limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A lab-made peptide that may help firm skin and soften lines, but human studies are limited so far.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that may help reduce fine lines and improve skin firmness by interfering with collagen-degrading enzymes.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still early.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A lab-made peptide that may help improve skin firmness and reduce fine lines, but human studies are limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A lab-made peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still early and results can vary.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A promising peptide that may help firm skin and soften lines, but more human studies are needed to confirm its effects.
Irritation
low
Source
semi-synthetic
beautyskincarepeptide
Read ingredient review3.8
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A synthetic peptide that helps firm skin and soften wrinkles by supporting collagen and elastin.
Irritation
low
Source
synthetic
beautyskincarepeptide
Read ingredient review4.0
A gentle, stabilized vitamin C peptide that may help brighten and firm skin with less irritation than pure L-ascorbic acid.
Irritation
low
Source
semi-synthetic
beautyskincareantioxidantpeptide
Read ingredient review