A synthetic ingredient used in nail products to help coatings stick and last longer, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic ingredient used in nail products to help coatings stick and last longer, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic plasticizer that helps nail polish stay flexible and resist chipping, but is not a moisturizer or active skincare ingredient.
Irritation
low
Source
synthetic
A synthetic film-forming ingredient used in nail products; limited safety data and potential for skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic film-former that helps makeup and nail polish last longer, but it's not a hydrating or active skincare ingredient.
Irritation
low
Source
synthetic
A synthetic bonding agent that helps nail products stick better, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic photoinitiator that makes UV-cured nail products harden quickly, but may cause skin irritation or allergic reactions in some people.
Irritation
moderate
Source
synthetic
A synthetic resin for nail products, not a hydrating or skin-friendly ingredient; potential allergen and not recommended for everyday skincare.
Irritation
moderate
Source
synthetic
A synthetic film former that helps nail polish last longer, but its connection to bisphenol A raises safety questions for some users.
Irritation
low
Source
synthetic
A synthetic crosslinking agent that strengthens nail coatings but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Butyl acetate helps nail polish glide on and dry quickly, but it can be drying or irritating for sensitive skin or frequent use.
Irritation
moderate
Source
synthetic
Butylphthalimide is a synthetic plasticizer that helps nail products stay flexible and resist chipping, but it has limited safety data and is best used in well-ventilated spaces.
Irritation
low
Source
synthetic
Cyclohexyl Methacrylate is a synthetic film-forming ingredient used mainly in nail products to create a hard, glossy finish, but it can be a skin sensitizer for some people.
Irritation
moderate
Source
synthetic
A synthetic ingredient that helps nail polish and lip products stay flexible and durable, but its safety profile is still being studied.
Irritation
low
Source
synthetic
This is a photoinitiator for UV-cured products, not a skincare ingredient; it may cause skin irritation in some people.
Irritation
moderate
Source
synthetic
An industrial plasticizer rarely used in leave-on skincare; best avoided for daily facial care due to limited safety data and potential irritation.
Irritation
moderate
Source
synthetic
A synthetic plasticizer that helps nail polish and lip products stay flexible and durable, but its safety data is limited compared to older alternatives.
Irritation
low
Source
synthetic
A synthetic crosslinker used in nail products to improve durability, but may cause skin sensitization in some individuals.
Irritation
moderate
Source
synthetic
A synthetic film former used in nail products to create a hard, glossy finish, but it can be a skin sensitizer for some people.
Irritation
moderate
Source
synthetic
A strong synthetic adhesive for nails and lashes, but can cause irritation if misused or if you have a sensitivity.
Irritation
moderate
Source
synthetic
A synthetic film-forming monomer used in nail products; may cause skin irritation in sensitive individuals and is best left to professional use.
Irritation
moderate
Source
synthetic
Ethyl acetate is an effective solvent for nail products but can be drying and irritating if used in high concentrations on skin.
Irritation
moderate
Source
synthetic
Ethyl cyanoacrylate is a strong adhesive used in nail products; it is not a skincare ingredient and can cause skin irritation or allergic reactions with direct contact.
Irritation
moderate
Source
synthetic
Ethyl Methacrylate is a key ingredient in many nail enhancement systems, but it can cause skin irritation and allergic reactions in some users.
Irritation
moderate
Source
synthetic
Ethyl Tosylamide is a synthetic plasticizer that makes nail polish more flexible and durable, but it can be a skin sensitizer for some people.
Irritation
moderate
Source
synthetic
Ethylene carbonate is a synthetic solvent that helps products spread and dry, but it can be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
A synthetic film-former that helps nail polish and long-wear makeup stay put, but may cause irritation for sensitive skin or nail beds.
Irritation
moderate
Source
synthetic
A synthetic resin that helps nail polish stick better and last longer, but it's not a moisturizer or active skincare ingredient.
Irritation
low
Source
synthetic
A synthetic resin that strengthens nail polish but may cause allergic reactions in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic plasticizer that helps nail polishes and other products form flexible, durable films — generally safe at low levels but not a skincare active.
Irritation
low
Source
synthetic
Film Former
GUANIDINE CARBONATE/HDI ISOCYANURATE TRIMER/MDI CROSSPOLYMER
A synthetic film-former that gives nail polish and long-wear makeup their tough, glossy finish, but it's not a skincare active.
Irritation
low
Source
synthetic
HEMA is a common nail ingredient that can cause allergic reactions in some people, so patch testing is recommended.
Irritation
moderate
Source
synthetic
HEMA Acetoacetate is a synthetic ingredient used in nail products for strong adhesion, but it can be a skin sensitizer for some people.
Irritation
moderate
Source
synthetic
HEMA Maleate helps products stick and last longer, but it can be a skin sensitizer for some people, especially in nail formulas.
Irritation
moderate
Source
synthetic
A synthetic film-forming ingredient used in nail products; it helps coatings adhere and last, but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Hexamethylene diisocyanate is a synthetic crosslinker used in nail products for durability, but it is a known irritant and sensitizer, making it unsuitable for leave-on skincare.
Irritation
high
Source
synthetic
A synthetic ester that helps nail polishes and hair products form flexible, durable films without making them brittle.
Irritation
low
Source
synthetic
A synthetic film-former that helps nail products last longer, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic resin that creates tough, shiny films in nail products, but may cause sensitivity in some users.
Irritation
moderate
Source
synthetic
A strong, fast-drying adhesive used in nail and lash products; effective but can cause skin irritation or allergic reactions in some people.
Irritation
moderate
Source
synthetic
A synthetic film former that helps nail products adhere and resist chipping, but it's not a moisturizer or active skincare ingredient.
Irritation
low
Source
synthetic
A synthetic film-forming ingredient used in nail products to improve durability and adhesion, but it is chemically related to bisphenol A, which raises some safety questions.
Irritation
low
Source
synthetic
Film Former
ISOPROPYLIDENEDIPHENYL BISOXYHYDROXYPROPYL METHACRYLATE/TMDI COPOLYMER
A synthetic film former that helps makeup and nail polish last longer, but offers no active skincare benefit.
Irritation
low
Source
synthetic
Isopropylphthalimide is a synthetic plasticizer that helps nail polishes and hair products stay flexible and durable, but its safety data is limited.
Irritation
low
Source
synthetic
A synthetic plasticizer found in some nail products; its safety data is limited and it may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Methacrylamide is a synthetic monomer used to create durable films in nail and hair products, but it can be a skin sensitizer and is best avoided in leave-on facial skincare.
Irritation
moderate
Source
synthetic
Methacrylic acid is a strong synthetic monomer used in nail products and adhesives; it can be irritating and is not a typical skincare ingredient.
Irritation
high
Source
synthetic
A synthetic ingredient that helps nail and hair products stick better and last longer, but may cause irritation for sensitive users.
Irritation
moderate
Source
synthetic
A synthetic ingredient that helps nail polish and hair products stick better and last longer, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic ingredient that helps nail and hair products stick better and last longer, but with limited safety data.
Irritation
moderate
Source
synthetic
A synthetic film-forming monomer mainly used in nail products; can be a skin sensitizer for some individuals.
Irritation
moderate
Source
synthetic
Methoxyethyl Acrylate is a synthetic film-former that helps nail products resist chipping and wear, but it can be a skin sensitizer for some individuals.
Irritation
moderate
Source
synthetic
A synthetic solvent that helps nail polish glide on smoothly and dry quickly, but may cause mild irritation for sensitive skin or prolonged contact.
Irritation
moderate
Source
synthetic
MIBK is a strong industrial solvent with limited cosmetic use; it can be irritating and is best avoided in leave-on skincare.
Irritation
high
Source
synthetic
Methyl methacrylate is a synthetic monomer used in nail products, but it can cause skin irritation and allergic reactions, especially in uncured form.
Irritation
moderate
Source
synthetic
A synthetic resin that helps nail polish stick and last longer, but it's not a moisturizing or skin-friendly ingredient.
Irritation
low
Source
synthetic
A synthetic ingredient that strengthens nail coatings but may cause skin irritation or allergic reactions in sensitive individuals.
Irritation
moderate
Source
synthetic
Nitrocellulose is a common film former in nail polish that provides a durable, glossy finish, but it is highly flammable in its raw form and can be drying to nails over time.
Irritation
low
Source
semi-synthetic
Oleoyl Epoxy Resin is a synthetic film former that helps nail polish and long-wear makeup last longer, but it has limited public research on skin safety.
Irritation
low
Source
synthetic
A synthetic film-former used in nail products; may cause skin irritation in sensitive individuals and is not typically found in leave-on facial skincare.
Irritation
moderate
Source
synthetic
A synthetic film-former that helps nail polish and mascara last longer, but may cause irritation for sensitive skin or eyes.
Irritation
moderate
Source
synthetic