A lab-made peptide that may help firm skin and soften fine lines, but research is still early.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A lab-made peptide that may help firm skin and soften fine lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness with low irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide that may help soften expression lines and improve skin firmness, but human studies are still limited.
Irritation
low
Source
synthetic
A gentle peptide that may help support skin firmness and reduce fine lines, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to support collagen and elastin, helping improve firmness and reduce fine lines.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A gentle peptide that helps calm reactive skin and reduce visible redness, making it a smart choice for sensitive skin routines.
Irritation
low
Source
synthetic
A gentle peptide that may help firm skin and reduce under-eye bags, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A gentle peptide that may help reduce visible redness and sensitivity over time, but results are subtle and not instant.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that targets under-eye concerns like puffiness and dark circles by supporting collagen and circulation.
Irritation
low
Source
synthetic
A gentle synthetic peptide that may help firm skin and reduce under-eye puffiness, with limited but promising early research.
Irritation
low
Source
synthetic
A gentle peptide that targets under-eye bags and dark circles by supporting circulation and reducing fluid buildup.
Irritation
low
Source
synthetic
A lab-made peptide that encourages collagen production for firmer, smoother skin with a very low risk of irritation.
Irritation
low
Source
synthetic
A synthetic plasticizer that helps nail polish stay flexible and resist chipping, but is not a moisturizer or active skincare ingredient.
Irritation
low
Source
synthetic
A gentle synthetic emollient that helps products glide on smoothly without clogging pores.
Irritation
low
Source
synthetic
Anti-wrinkle agent
Acetyl Trifluoromethylphenyl Valylglycine
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, but results are subtle and not as strong as injectable treatments.
Irritation
low
Source
synthetic
A gentle, low-irritation emollient that helps products spread smoothly and keeps nail polish flexible.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical alternative to injectables.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften lines, but long-term human data is still limited.
Irritation
low
Source
synthetic
A gentle amino acid derivative that may help brighten skin and reduce dark spots with minimal irritation.
Irritation
low
Source
semi-synthetic
Acetyl Tyrosine is a gentle amino acid derivative that helps maintain an even skin tone and supports the skin's natural antioxidant defenses.
Irritation
low
Source
semi-synthetic
A gentle, ginger-derived antioxidant that helps defend against pollution and UV stress without the irritation of pure ginger.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder version of neuropeptides.
Irritation
low
Source
synthetic
A gentle, semi-synthetic emollient and fragrance ingredient derived from amyris oil, offering a subtle woody scent with good skin tolerance.
Irritation
low
Source
semi-synthetic
A gentle, amino-acid-based ingredient that helps hydrate and plump the skin by supporting its natural moisture network.
Irritation
low
Source
semi-synthetic
Emollient
Acetylated C10-40 Hydroxyalkyl Acid Cholesterol/Lanosterol Esters
A gentle, skin-softening lipid that strengthens the skin barrier without clogging pores.
Irritation
low
Source
semi-synthetic
A modified clove extract that may offer antioxidant benefits, but its acetylation process and potential for irritation require cautious use.
Irritation
moderate
Source
semi-synthetic
A gentle, modified plant oil that helps soften skin and improve product texture, but research on its specific benefits is still limited.
Irritation
low
Source
semi-synthetic
A gentle, modified wood extract that may help protect skin from environmental stress, but research on its specific benefits is still limited.
Irritation
low
Source
semi-synthetic
A gentle, non-greasy emollient that helps soften skin and improve product feel without clogging pores.
Irritation
low
Source
semi-synthetic
A gentle synthetic emollient that softens skin and improves product feel, with a low risk of irritation or clogged pores.
Irritation
low
Source
synthetic
A gentle, semi-synthetic emollient that softens skin and helps other ingredients spread smoothly.
Irritation
low
Source
semi-synthetic
A gentle, non-greasy emollient derived from castor oil that helps soften and smooth the skin without clogging pores.
Irritation
low
Source
semi-synthetic
A gentle, semi-synthetic emollient that softens skin and improves product feel without common irritation or clogging concerns.
Irritation
low
Source
semi-synthetic
Antioxidant
JUNIPERUS VIRGINIANA EXTRACT ACETYLATED-HYDROGENATED
A modified juniper extract that may offer antioxidant benefits, but research on this specific form is limited.
Irritation
low
Source
semi-synthetic
A gentle, modified lanolin that softens skin but may clog pores for some people.
Irritation
low
Source
semi-synthetic
A semi-synthetic emollient that softens skin but may clog pores for some; not suitable for vegans.
Irritation
low
Source
semi-synthetic
A semi-synthetic emollient that softens skin but may clog pores for some people, especially those prone to breakouts.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived emollient that helps soften skin and improve product texture without common irritation.
Irritation
low
Source
semi-synthetic
A gentle, antioxidant-rich botanical extract that may help calm skin, but research on the acetylated form is limited.
Irritation
low
Source
semi-synthetic
A modified wood extract used mainly for scent and mild skin conditioning, but research is limited.
Irritation
low
Source
semi-synthetic
A gentle emollient derived from lanolin that softens skin but may clog pores for some people.
Irritation
low
Source
semi-synthetic
A rich emollient that softens skin but may clog pores for some, especially those prone to breakouts.
Irritation
low
Source
semi-synthetic
A semi-synthetic emollient that softens skin but may clog pores for some, and is not suitable for vegan or certain religious lifestyles.
Irritation
low
Source
semi-synthetic
A gentle, aromatic ingredient from lavandin that may offer mild soothing benefits, but its acetylation process alters its properties and safety profile.
Irritation
moderate
Source
semi-synthetic
A modified lavender extract that offers a gentle scent and potential soothing benefits, but research on the acetylated version is limited.
Irritation
low
Source
semi-synthetic
A gentle, semi-synthetic emollient that softens skin and improves product feel without common irritation or clogging concerns.
Irritation
low
Source
semi-synthetic
A synthetic fragrance ingredient that adds scent but offers no skin benefit and may irritate sensitive skin.
Irritation
moderate
Source
synthetic
A gentle, modified oil that softens skin and improves the feel of products without clogging pores.
Irritation
low
Source
semi-synthetic
A modified plant extract with antioxidant potential, but research is limited and its benefits are not well-established.
Irritation
low
Source
semi-synthetic
Skin conditioning
PELARGONIUM RADULA LEAF EXTRACT ACETYLATED
A modified plant extract with potential antioxidant benefits, but research is limited and it may not be a standout ingredient.
Irritation
low
Source
semi-synthetic
A gentle, sugar-derived emollient that helps products feel silky and spread smoothly without clogging pores.
Irritation
low
Source
semi-synthetic
A gentle, antioxidant-rich extract from Swiss pine that may help protect skin from environmental stress, though research is still emerging.
Irritation
low
Source
semi-synthetic
A gentle, antioxidant-rich ingredient that may help calm skin and protect against environmental stress.
Irritation
low
Source
semi-synthetic
Acetylbenzofuran is a synthetic fragrance ingredient with limited safety data; it may cause skin irritation in sensitive individuals and is best avoided in leave-on products for reactive skin.
Irritation
moderate
Source
synthetic
Acetylcedrene is a synthetic woody fragrance ingredient that is generally safe at low concentrations but may cause skin sensitivity in some individuals.
Irritation
low
Source
synthetic