A gentle, vitamin B6-inspired ingredient that may help calm irritation and support the skin barrier, though research is still limited.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A gentle, vitamin B6-inspired ingredient that may help calm irritation and support the skin barrier, though research is still limited.
Irritation
low
Source
synthetic
A gentle, emerging exfoliant that may brighten skin and improve texture with less irritation than traditional acids.
Irritation
low
Source
synthetic
A gentle, active form of vitamin B6 that helps calm skin and strengthen the moisture barrier without irritation.
Irritation
low
Source
semi-synthetic
Pyridoxine (vitamin B6) is a gentle, water-soluble vitamin that may help regulate oil production and support skin barrier health, though research is still emerging.
Irritation
low
Source
synthetic
A gentle, oil-friendly form of vitamin B6 that helps calm skin and support a healthy barrier without irritation.
Irritation
low
Source
semi-synthetic
A gentle, fat-soluble form of vitamin B6 that may help protect skin from environmental stress and support a healthy-looking complexion.
Irritation
low
Source
semi-synthetic
A gentle, fat-soluble form of vitamin B6 that helps calm redness and protect skin from environmental stress.
Irritation
low
Source
semi-synthetic
A gentle, oil-friendly form of vitamin B6 that helps protect skin from environmental stress and supports a healthy-looking complexion.
Irritation
low
Source
semi-synthetic
A gentle, dual-action ingredient that pairs vitamin B6 with a licorice root compound to help calm redness and support skin comfort.
Irritation
low
Source
semi-synthetic
A gentle, stabilized vitamin B6 derivative that may help calm skin and fight free radicals, though research is still emerging.
Irritation
low
Source
semi-synthetic
A gentle antioxidant ingredient that may help calm skin and support a healthy glow, but research on its topical benefits is still limited.
Irritation
low
Source
semi-synthetic
A gentle exfoliating ingredient that combines vitamin B6 with salicylic acid to help smooth skin and reduce redness.
Irritation
moderate
Source
semi-synthetic
A gentle, dual-action ingredient that combines vitamin B6 with serine to help calm irritation and support a healthy skin barrier.
Irritation
low
Source
semi-synthetic
A stable, oil-soluble form of vitamin B6 that helps protect skin from environmental stress and supports a healthy-looking complexion.
Irritation
low
Source
semi-synthetic
A gentle, oil-soluble vitamin B6 derivative that helps protect skin from environmental stress and supports a healthy-looking complexion.
Irritation
low
Source
semi-synthetic
A synthetic antioxidant that may help protect skin from oxidative stress, but human skincare research is still emerging.
Irritation
moderate
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more independent research is needed.
Irritation
low
Source
synthetic
A synthetic ingredient that may help hydrate and support the skin barrier, but research is still early.
Irritation
low
Source
synthetic
A natural fragrance ingredient with potential antioxidant benefits, but limited research and a moderate risk of skin irritation.
Irritation
moderate
Source
natural
A natural wood-derived extract that may help calm skin and provide antioxidant benefits, though research is still emerging.
Irritation
low
Source
natural
Pyrophyllite is a gentle clay that helps absorb excess oil and improve product texture, but its skincare benefits are not well-studied.
Irritation
low
Source
natural
A gentle fern extract with antioxidant potential, but research on its skincare benefits is still limited.
Irritation
low
Source
natural
A synthetic ingredient that may help slow hair thinning by reducing collagen buildup around hair follicles, but results vary and it works best as part of a comprehensive hair care routine.
Irritation
low
Source
synthetic
Hair growth stimulant
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE OXOTHIAZOLIDINECARBOXYLATE
A synthetic molecule that may help reduce hair thinning by supporting hair follicle activity, but research is still limited.
Irritation
low
Source
synthetic
PQQ is a potent antioxidant that may help protect skin from oxidative stress and support cellular energy, but human skincare research is still limited.
Irritation
low
Source
biotech
PQQ is a cutting-edge antioxidant that may help energize skin cells and fight signs of aging, but research in topical skincare is still early.
Irritation
low
Source
biotech
An experimental antioxidant derivative with limited cosmetic research; promising in theory but not yet proven in everyday skincare.
Irritation
low
Source
semi-synthetic
Pyruvic acid is a potent exfoliant similar to AHAs, but it may be less irritating for some skin types while still improving texture and acne.
Irritation
moderate
Source
synthetic
Quartz can provide gentle physical exfoliation, but its sharp edges may irritate sensitive skin if not finely milled.
Irritation
moderate
Source
natural
Quassia Wood Powder is a gentle botanical astringent that may help calm skin and reduce excess oil, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
Quassin is a plant-derived compound with potential anti-inflammatory and antimicrobial benefits, but research in cosmetics is still limited.
Irritation
low
Source
natural
Quaternium-14 is an effective preservative and antistatic agent, but its potential for skin irritation means it is best suited for rinse-off products.
Irritation
moderate
Source
synthetic
Quaternium-15 is an effective preservative but controversial due to its formaldehyde-releasing nature, which can cause skin irritation and allergic reactions in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic conditioning ingredient that reduces static and softens hair, but may cause buildup with frequent use.
Irritation
low
Source
synthetic
A safe, modified clay that improves product texture and stability without major skin concerns.
Irritation
low
Source
semi-synthetic
A safe, non-irritating thickener that gives makeup and skincare a smooth, creamy feel without clogging pores.
Irritation
low
Source
semi-synthetic
A synthetic conditioning ingredient that helps reduce static and improve manageability, but may be too heavy for fine or acne-prone skin.
Irritation
low
Source
synthetic
A modified clay that helps control oil and improve product texture, generally safe for most skin types.
Irritation
low
Source
semi-synthetic
Quaternium-22 is a gentle conditioning ingredient that reduces static and improves feel in hair and skin products, with a low risk of irritation.
Irritation
low
Source
synthetic
Quaternium-24 is a gentle conditioning ingredient that helps reduce frizz and static without heavy buildup.
Irritation
low
Source
synthetic
Quaternium-27 is a mild conditioning ingredient that helps detangle hair and reduce static, but it may not suit very fine or easily weighed-down hair types.
Irritation
low
Source
synthetic
Quaternium-30 is a synthetic conditioning ingredient that helps reduce frizz and static in hair while adding a silky feel, but it may not suit those avoiding silicones or heavy polymers.
Irritation
low
Source
synthetic
Quaternium-33 is a synthetic conditioning ingredient that helps reduce static and improve manageability, but it may cause irritation for sensitive skin or clog pores in some people.
Irritation
moderate
Source
synthetic
Quaternium-43 is a synthetic conditioning ingredient that helps reduce static and improve hair manageability, but it may not suit very sensitive scalps.
Irritation
low
Source
synthetic
Quaternium-45 is a synthetic conditioning ingredient that reduces static and improves manageability in hair products, with a low risk of irritation.
Irritation
low
Source
synthetic
Quaternium-51 is a gentle synthetic conditioner that helps reduce static and improve the feel of hair and skin without heavy buildup.
Irritation
low
Source
synthetic
Quaternium-52 is a gentle synthetic conditioner that reduces frizz and static without heavy buildup, but it offers no active skincare benefits.
Irritation
low
Source
synthetic
A gentle synthetic conditioner that helps detangle hair and reduce flyaways without heavy buildup.
Irritation
low
Source
synthetic
Quaternium-56 is a synthetic conditioning agent that reduces static and improves hair feel, but its benefits are mostly cosmetic and temporary.
Irritation
low
Source
synthetic
Quaternium-60 is a synthetic conditioning agent that reduces static and improves manageability in hair products, with a low risk of irritation for most users.
Irritation
low
Source
synthetic
A gentle conditioning ingredient that helps reduce static and improve manageability in hair products, with a low risk of irritation.
Irritation
low
Source
synthetic
A gentle synthetic conditioner that helps detangle hair and reduce frizz without heavy buildup.
Irritation
low
Source
synthetic
Quaternium-70 is a synthetic conditioning ingredient that helps reduce frizz and static in hair, but it may not suit those with very fine or easily weighed-down hair.
Irritation
low
Source
synthetic
Quaternium-71 is a gentle synthetic conditioner that helps detangle hair and soften skin without heavy buildup.
Irritation
low
Source
synthetic
Quaternium-72 is a synthetic conditioning ingredient that helps reduce static and improve manageability in hair products, with a low risk of irritation for most users.
Irritation
low
Source
synthetic
Quaternium-73 is a synthetic preservative booster that helps keep rinse-off products fresh, but it may cause irritation for sensitive skin types.
Irritation
moderate
Source
synthetic
A gentle, plant-derived conditioning agent that reduces frizz and static without heavy buildup.
Irritation
low
Source
semi-synthetic
A gentle conditioning ingredient that helps reduce static and improve manageability in hair products, with mild film-forming benefits for skin.
Irritation
low
Source
semi-synthetic
A synthetic conditioning agent that helps reduce frizz and static in hair, but may not suit all hair types.
Irritation
low
Source
synthetic
A gentle synthetic conditioner that reduces static and smooths hair without heavy buildup.
Irritation
low
Source
synthetic