A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still emerging.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-62 is a lab-made peptide that may help support collagen and elastin for a firmer, smoother look, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-67 is a lab-made peptide that may help reduce fine lines and support skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
A duo of synthetic peptides that signal skin to boost collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-70 is a lab-made peptide that may help firm skin and soften lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-72 is a lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-74 is a lab-made peptide that may help reduce the look of fine lines by signaling skin cells to act younger, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to look firmer and smoother, with low irritation risk and moderate research support.
Irritation
low
Source
synthetic
SH-Polypeptide-77 is a lab-made peptide that may help reduce fine lines by encouraging your skin to produce more collagen, but results vary and it works best with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-78 is a synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-80 is a lab-made peptide that may help support firmer-looking skin, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften wrinkles, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-86 is a synthetic peptide that may help reduce fine lines by signaling skin cells to produce more collagen, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-89 is a lab-made peptide that may help improve skin firmness and hydration, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-90 is a soy-derived peptide that may help firm and smooth skin by supporting collagen production, but more human studies are needed to confirm its effects.
Irritation
low
Source
semi-synthetic
SH-Polypeptide-91 is a lab-made peptide that may help reduce fine lines by signaling skin cells to produce more collagen, though human studies are limited.
Irritation
low
Source
synthetic
SH-Polypeptide-92 is a lab-made peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that may help reduce fine lines by signaling skin to produce more collagen, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and support firmer-looking skin, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
A synthetic peptide duo that may help soften fine lines and support firmer-looking skin, though long-term human data is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-99 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin by signaling collagen production, but human studies are limited.
Irritation
low
Source
synthetic
A gentle, silica-delivering ingredient that may help improve skin firmness and elasticity over time.
Irritation
low
Source
semi-synthetic
A gentle peptide from silkworm silk that may support collagen and skin firmness, but human research is still limited.
Irritation
low
Source
biotech
Anti-Aging Agent
SR-Oligopeptide-150, Silkworm Polypeptide-2, Dipeptide-19, Hexapeptide-40
A promising peptide blend that may help firm skin, but research is still early and results vary.
Irritation
low
Source
synthetic
A biotech peptide from silkworms that may support skin firmness and hydration, but research is still early.
Irritation
low
Source
biotech
Anti-aging agent
SODIUM ACETYL ETHYLCARBOXYL METHYLTHIAZOLIDINE CARBOXYLATE
A synthetic peptide-like ingredient that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A silicon-modified seaweed derivative that may help firm and plump skin by supporting collagen and moisture.
Irritation
low
Source
semi-synthetic
Spermidine is a promising anti-aging ingredient that encourages skin cell renewal and may help reduce fine lines, but human research is still limited.
Irritation
low
Source
natural
A novel synthetic peptide inspired by horse proteins that may help improve skin firmness and reduce fine lines, but human research is still limited.
Irritation
low
Source
synthetic
A lab-made peptide inspired by spider silk that may help temporarily firm and smooth skin, but human research is still limited.
Irritation
low
Source
synthetic
Telmesteine is a synthetic peptide-like ingredient that may help firm and smooth skin, but research is still emerging and it is not widely studied in humans.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce wrinkle depth, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
Tetrapeptide-11 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still early and results can be subtle.
Irritation
low
Source
synthetic
Tetrapeptide-21 is a lab-made peptide that signals skin to produce more collagen, helping soften fine lines over time with a very low risk of irritation.
Irritation
low
Source
synthetic
Tetrapeptide-38 is a lab-made peptide that signals skin cells to boost collagen production, helping to smooth fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
Tetrapeptide-39 is a lab-made peptide that may help firm skin and reduce fine lines, but research is still early and it's less proven than more common peptides.
Irritation
low
Source
synthetic
Tetrapeptide-44 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-45 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-55 is a lab-made peptide that may help support skin firmness and reduce the look of fine lines, but research is still early.
Irritation
low
Source
synthetic
A newer synthetic peptide that may help improve skin firmness and smoothness, but research is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce wrinkles, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that may help improve skin firmness and smooth fine lines, but research is still early.
Irritation
low
Source
synthetic
A plant-derived peptide blend that may help firm skin and soften wrinkles, but research is still early.
Irritation
low
Source
biotech
A lab-made peptide from silkworms that may help firm skin and reduce fine lines, but research is still early.
Irritation
low
Source
biotech
Anti-Aging Agent
TRIETHOXYSILYLPROPYL ACETYL HYDROXYPROLINATE
A gentle, silicon-stabilized amino acid that may support collagen and improve skin firmness with low irritation risk.
Irritation
low
Source
semi-synthetic
A synthetic peptide-like ingredient that helps soften expression lines by calming facial muscles, offering a gentler alternative to neurotoxins.
Irritation
low
Source
synthetic
Tripeptide-34 is a lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness by signaling collagen production, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help smooth wrinkles and improve skin firmness with very low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
Tripeptide-56 is a synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic