A gentle, synthetic ingredient designed to calm irritated skin and reduce redness, though research is still emerging.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A gentle, synthetic ingredient designed to calm irritated skin and reduce redness, though research is still emerging.
Irritation
low
Source
synthetic
A gentle, plant-derived ingredient that helps calm redness and irritation without the side effects of stronger anti-inflammatories.
Irritation
low
Source
natural
A gentle, oil-friendly derivative of licorice root that helps calm redness and soothe sensitive skin without irritation.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived ingredient that helps calm redness and irritation, making it a great choice for sensitive or reactive skin.
Irritation
low
Source
natural
A marine extract with potential calming benefits, but research is limited and sustainability concerns exist.
Irritation
low
Source
natural
A gentle plant extract with potential soothing and antioxidant benefits, but research is still emerging.
Irritation
low
Source
natural
A gentle botanical extract with traditional use for calming irritated skin, though modern research is still limited.
Irritation
low
Source
natural
Grindelia Extract is a gentle botanical with soothing potential, best for calming irritated or sensitive skin, though research is still emerging.
Irritation
low
Source
natural
A gentle, antioxidant-rich oil from the gromwell root that helps calm skin and fight environmental stress.
Irritation
low
Source
natural
A gentle, plant-based gum extract with antioxidant and soothing potential, but research is limited.
Irritation
low
Source
natural
Guaiazulene is a gentle, blue-pigmented compound from chamomile-like plants that helps calm redness and soothe sensitive skin.
Irritation
low
Source
natural
Harpagide is a gentle, plant-derived compound that may help calm irritated skin and fight free radical damage, though research is still early.
Irritation
low
Source
natural
A gentle, plant-based powder that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
A gentle, lab-made ingredient that helps dial down skin reactivity and soothe irritation without harsh side effects.
Irritation
low
Source
synthetic
A gentle, aromatic water from the Hinoki cypress tree that may help soothe skin and provide a calming sensory experience, though research is still emerging.
Irritation
low
Source
natural
A gentle, plant-based extract that helps calm and hydrate the skin, though research is still emerging.
Irritation
low
Source
natural
A gentle fermented ingredient that may help calm skin and provide antioxidant benefits, though research is still emerging.
Irritation
low
Source
biotech
A gentle, plant-based powder that helps calm irritated skin and provides antioxidant protection, ideal for sensitive or acne-prone skin.
Irritation
low
Source
natural
A gentle, plant-derived water that helps calm irritation and provides antioxidant protection, ideal for sensitive or reactive skin.
Irritation
low
Source
natural
A gentle, stabilized version of chamomile-derived bisabolol that helps calm irritated skin without causing breakouts.
Irritation
low
Source
semi-synthetic
A gentle, antioxidant-rich botanical extract that may help calm skin, but research is limited and hydrogenation alters its natural composition.
Irritation
low
Source
natural
A gentle, biotech-derived extract that may help calm irritation and support skin hydration, though research is still emerging.
Irritation
low
Source
biotech
A gentle, water-soluble aloe derivative that hydrates and calms skin, ideal for sensitive or irritated complexions.
Irritation
low
Source
natural
A gentle, antioxidant-rich seaweed extract that may help calm skin and protect against environmental stress.
Irritation
low
Source
natural
A gentle, plant-derived humectant that helps hydrate and calm the skin, with early research suggesting antioxidant benefits.
Irritation
low
Source
natural
A gentle, hydrolyzed version of calendula extract that soothes irritation and supports skin barrier function with low risk of irritation.
Irritation
low
Source
natural
A gentle, biotech-derived yeast extract that may help soothe and condition the skin, but research is still emerging.
Irritation
low
Source
biotech
Hydrolyzed coral is a mineral-rich ingredient that may help soothe and hydrate the skin, but scientific evidence is limited and sustainability concerns exist.
Irritation
low
Source
natural
A gentle, hydrating seaweed extract that may help calm irritation and support the skin barrier.
Irritation
low
Source
natural
A gentle, licorice-derived ingredient that helps calm redness and even out skin tone without irritation.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived extract that may help calm irritation and support skin hydration, though research is still emerging.
Irritation
low
Source
natural
A gentle, plant-derived humectant that helps soothe and hydrate the skin, with some antioxidant potential.
Irritation
low
Source
natural
A gentle, fermented yeast extract that may help calm and condition the skin, though research is still limited.
Irritation
low
Source
biotech
A gentle, plant-derived ingredient that may help calm skin and provide antioxidant support, though research is still emerging.
Irritation
low
Source
natural
A gentle, plant-based ingredient that helps calm irritated skin and provides antioxidant protection without clogging pores.
Irritation
low
Source
natural
A gentle, plant-based ingredient that may help calm irritation and provide antioxidant protection, though research is still early.
Irritation
low
Source
natural
A gentle, plant-based extract that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
Hydrolyzed oat flour is a gentle, soothing ingredient that calms irritation and supports the skin barrier, making it ideal for sensitive or reactive skin.
Irritation
low
Source
natural
Soothing Agent
HYDROLYZED PLEUROTUS NEBRODENSIS MYCELIUM EXTRACT
A gentle mushroom-derived ingredient that may calm irritation and support skin hydration, though research is still emerging.
Irritation
low
Source
natural
Hydrolyzed Sponge is a gentle, marine-based ingredient that may help calm irritated skin and support moisture retention, though research is still emerging.
Irritation
low
Source
natural
A gentle, plant-derived ingredient that may help calm redness and provide antioxidant support, though research is still emerging.
Irritation
low
Source
natural
A gentle, fermented yeast extract that may help calm skin and provide antioxidant support, though research is still emerging.
Irritation
low
Source
biotech
A gentle, antioxidant-rich botanical extract that may help calm irritated skin, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
A gentle, antioxidant-rich botanical extract that helps calm skin and fight free radicals, but is not a substitute for medical treatment.
Irritation
low
Source
natural
A gentle, lab-made ingredient that helps calm irritated skin and reduce redness without harsh side effects.
Irritation
low
Source
synthetic
A gentle botanical extract with antioxidant and soothing potential, though human studies are limited.
Irritation
low
Source
natural
A gentle, natural extract that helps calm irritation and provides antioxidant protection, ideal for sensitive or reactive skin.
Irritation
low
Source
natural
Soothing agent
IMIDAZOLYLPHENYLETHYL NAPHTHYLSULFONYL ASPARAGINE
A synthetic peptide-like ingredient that may help calm skin sensitivity, but research is still emerging.
Irritation
low
Source
synthetic
Imiloxan HCl is a synthetic compound with limited research in cosmetics; its safety and efficacy for skincare are not well-established.
Irritation
moderate
Source
synthetic
A gentle, plant-derived powder that may help calm skin and provide antioxidant protection, though research is still emerging.
Irritation
low
Source
natural
A gentle, synthetic amino-acid derivative that may help calm irritation and reinforce the skin barrier, though research is still early.
Irritation
low
Source
synthetic
Iritone is a gentle, plant-derived ingredient that may help calm irritated skin, but research is limited and it's not a proven powerhouse.
Irritation
low
Source
natural
Isocineole is a gentle, plant-derived compound that may help calm skin and provide a cooling sensation, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
A synthetic compound that may help calm skin and support its natural defenses, but research is still early.
Irritation
low
Source
synthetic
A synthetic soothing ingredient that mimics natural skin-signaling peptides to help reduce visible redness and discomfort.
Irritation
low
Source
synthetic
A gentle, plant-based extract that may help calm irritated skin and provide antioxidant support, though research is still emerging.
Irritation
low
Source
natural
A gentle, water-based botanical extract that may help calm skin and provide antioxidant protection, though research is still emerging.
Irritation
low
Source
natural
A gentle plant extract that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
A gentle botanical extract that may help calm irritated skin and provide antioxidant protection, but research is still emerging.
Irritation
low
Source
natural
A gentle, plant-based extract that helps calm and hydrate the skin, ideal for sensitive or irritated complexions.
Irritation
low
Source
natural