A lab-made peptide that signals skin to appear firmer and smoother, with low irritation potential.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A lab-made peptide that signals skin to appear firmer and smoother, with low irritation potential.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and reduce puffiness, especially around the eyes, with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A gentle peptide that may help reduce visible redness and sensitivity over time, but results are subtle and not instant.
Irritation
low
Source
synthetic
A lab-made peptide that may help improve skin firmness and smooth fine lines, but more independent research is needed to confirm its effects.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften expression lines, but human studies are limited.
Irritation
low
Source
synthetic
A gentle peptide that may help reduce visible redness and support a calmer, more even complexion over time.
Irritation
low
Source
synthetic
A gentle peptide that helps calm visible skin reactivity and support a more resilient-looking complexion.
Irritation
low
Source
synthetic
A synthetic peptide that helps support collagen and skin firmness, generally well-tolerated and suitable for most skin types.
Irritation
low
Source
synthetic
A well-tolerated peptide that may help reduce fine lines and improve skin firmness with consistent use.
Irritation
low
Source
synthetic
A novel biotech peptide that shows promise for anti-aging, but human research is still limited.
Irritation
low
Source
biotech
Anti-aging agent
Nicotiana Benthamiana Hexapeptide-40, SH-Polypeptide-6
A plant-derived peptide that may help smooth fine lines and support collagen, but research is still early.
Irritation
low
Source
biotech
A biotech-derived peptide from tobacco plants that may help firm skin and soften fine lines, but human research is still limited.
Irritation
low
Source
biotech
Anti-aging agent
Nicotiana Benthamiana SH-Polypeptide-15 Hexapeptide-40
A novel plant-derived peptide complex that may help support collagen production, but research is still early and it's less proven than well-studied peptides.
Irritation
low
Source
biotech
A plant-based peptide that may help support collagen and skin firmness, but research is still early.
Irritation
low
Source
biotech
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more human studies are needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but human data is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation risk.
Irritation
low
Source
synthetic
A gentle peptide-niacinamide hybrid that helps firm skin and soften lines without irritation.
Irritation
low
Source
semi-synthetic
A promising synthetic peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that targets melanin production to help fade dark spots and even out skin tone, with low irritation potential.
Irritation
low
Source
synthetic
A targeted peptide that may help fade under-eye circles by improving blood flow and reducing pigment buildup.
Irritation
low
Source
synthetic
Anti-aging agent
NONAPEPTIDE-29 AMIDO CARBOXYMETHYL HYDROXYLIMINOMETHYLBENZAMIDO SH-DSRNA-1
A lab-made peptide complex that may help firm skin and soften lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide duo that may help soften expression lines and improve skin firmness with a low risk of irritation.
Irritation
low
Source
synthetic
A lab-made peptide that may help soften expression lines and improve skin firmness, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce the look of fine lines and improve skin firmness, though research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but more independent human studies are needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
A lab-made peptide that may help soften expression lines over time, but independent human research is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Octapeptide-35 is a lab-made peptide that may help support collagen and reduce fine lines, but human research is still limited.
Irritation
low
Source
synthetic
Octapeptide-36 is a lab-made peptide that may help reduce the look of fine lines and wrinkles, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide duo that may help reduce fine lines and improve skin firmness, but results vary and it works best in a consistent routine.
Irritation
low
Source
biotech
A synthetic peptide that may help reduce fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften wrinkles, but human studies are limited.
Irritation
low
Source
synthetic
A peptide duo that may help soften fine lines and support skin firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften lines, but human studies are limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm and smooth skin by signaling collagen production, but long-term human data is still limited.
Irritation
low
Source
synthetic
Oligopeptide-45 is a synthetic peptide that may help support collagen and improve skin firmness, but research is limited compared to more established peptides.
Irritation
low
Source
synthetic
A lab-made peptide-polymer blend that may help plump and firm skin, but research is still early and benefits vary by formulation.
Irritation
low
Source
semi-synthetic
Oligopeptide-62 is a synthetic peptide that may help reduce fine lines and improve skin firmness by signaling collagen production, though human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
Oligopeptide-72 is a lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that supports skin barrier function and hydration, with low irritation potential.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
Anti-wrinkle agent
SR-Oligopeptide-91, Clostridium Botulinum Polypeptide-1
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, but results are subtle and not comparable to injectables.
Irritation
low
Source
synthetic
Ovex is a synthetic peptide complex that may help improve skin firmness and reduce fine lines, but independent research is limited.
Irritation
low
Source
synthetic
Skin conditioning agent
OXO AZAANDROSTENE CARBOXYLOYL DECAPEPTIDE-18
A synthetic peptide that may help firm and smooth skin by mimicking a hormone signal, but research is still emerging.
Irritation
low
Source
synthetic
A peptide that helps protect collagen from sugar damage and supports firmer, more resilient skin over time.
Irritation
low
Source
semi-synthetic
A synthetic peptide that helps support collagen production and reduce the appearance of fine lines with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic