A synthetic preservative that helps keep products fresh, but may cause irritation for sensitive skin types.
Irritation
moderate
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic preservative that helps keep products fresh, but may cause irritation for sensitive skin types.
Irritation
moderate
Source
synthetic
Isopropylamine is a synthetic pH adjuster used in tiny amounts to stabilize formulas, but it can be irritating and is rarely a featured ingredient in skincare.
Irritation
moderate
Source
synthetic
A strong synthetic detergent that effectively removes oil and dirt but may be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
A synthetic berberine derivative with antimicrobial potential, but limited human safety data and a moderate irritation risk.
Irritation
moderate
Source
synthetic
A widely used synthetic fragrance that adds a warm, woody scent; generally safe but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A potentially gentler cousin of classic benzoyl peroxide that fights acne bacteria and helps clear pores, but may still cause dryness or irritation in sensitive skin.
Irritation
moderate
Source
synthetic
Anti-aging agent
ISOPROPYLCHROMENAMIDO FLUOROBENZYL METHANESULFONAMIDE
A novel synthetic compound that may help reduce the look of fine lines and wrinkles, but research is still early and it's found mainly in premium products.
Irritation
low
Source
synthetic
A synthetic ingredient that helps condition skin and improve product feel, but research on its long-term benefits is still limited.
Irritation
low
Source
synthetic
A synthetic peptide-like ingredient that helps soften expression lines by temporarily relaxing facial muscles, offering a gentler alternative to injectables.
Irritation
low
Source
synthetic
A gentle, coconut-derived emollient that softens skin without feeling greasy, suitable for most skin types.
Irritation
low
Source
semi-synthetic
A synthetic film former that helps nail products adhere and resist chipping, but it's not a moisturizer or active skincare ingredient.
Irritation
low
Source
synthetic
A synthetic fragrance ingredient that adds scent but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Film Former
ISOPROPYLIDENEDIPHENOL BISHYDROXYPROPYL PEG-180
A synthetic film-former that helps products spread smoothly and stay put, but its connection to bisphenol A raises caution for some users.
Irritation
low
Source
synthetic
A synthetic film-forming ingredient used in nail products to improve durability and adhesion, but it is chemically related to bisphenol A, which raises some safety questions.
Irritation
low
Source
synthetic
Film Former
ISOPROPYLIDENEDIPHENYL BISOXYHYDROXYPROPYL ACRYLATE
A synthetic film-former that helps products stay put and resist water, but offers no active skincare benefit.
Irritation
low
Source
synthetic
Film Former
ISOPROPYLIDENEDIPHENYL BISOXYHYDROXYPROPYL METHACRYLATE/TMDI COPOLYMER
A synthetic film former that helps makeup and nail polish last longer, but offers no active skincare benefit.
Irritation
low
Source
synthetic
Isopropylindanone is a synthetic scent ingredient that adds a woody note but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A lightweight synthetic emollient that spreads easily and leaves a non-greasy finish, generally well-tolerated by most skin types.
Irritation
low
Source
synthetic
Isopropylmethylhexenal is a synthetic fragrance compound that adds a floral-woody scent, but it may cause skin irritation or allergic reactions in sensitive individuals.
Irritation
moderate
Source
synthetic
Isopropylmethylhexenol is a synthetic fragrance ingredient that adds a floral-green scent but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic scent ingredient that can make products smell pleasant but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Isopropylparaben is an effective preservative but has raised some safety concerns due to its potential endocrine activity; many brands now avoid it.
Irritation
low
Source
synthetic
A common synthetic fragrance ingredient that provides a floral scent but can be a skin sensitizer for some people.
Irritation
moderate
Source
synthetic
A synthetic fragrance ingredient that adds pleasant scent but may cause skin sensitivity in some people.
Irritation
moderate
Source
synthetic
A common synthetic fragrance that adds a pleasant floral scent but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Isopropylphthalimide is a synthetic plasticizer that helps nail polishes and hair products stay flexible and durable, but its safety data is limited.
Irritation
low
Source
synthetic
Isopropylquinoline is a synthetic fragrance ingredient with limited safety data; it may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Isopulegol is a natural minty fragrance component that can be sensitizing for some, especially at higher concentrations.
Irritation
moderate
Source
natural
Isopulegyl acetate is a synthetic fragrance ingredient that provides a fresh, minty scent but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Isopulegyl Formate is a synthetic fragrance ingredient that adds a fresh, minty scent, but it offers no skincare benefits and may cause irritation in sensitive individuals.
Irritation
low
Source
synthetic
A gentle plant antioxidant that helps shield skin from pollution and UV damage while supporting a brighter, more even complexion.
Irritation
low
Source
natural
A gentle plant-derived antioxidant that helps defend skin against pollution and UV-related damage without irritation.
Irritation
low
Source
natural
Isorhamnetin is a plant-derived antioxidant that helps shield skin from environmental stress and may calm irritation, but human studies are still limited.
Irritation
low
Source
natural
Isosorbide is a gentle, plant-based humectant that hydrates skin without stickiness, making it a good alternative to glycerin or hyaluronic acid.
Irritation
low
Source
natural
A lightweight, plant-derived emollient that hydrates and softens skin without feeling greasy, making it a great alternative to silicones or heavier oils.
Irritation
low
Source
semi-synthetic
A gentle, non-greasy emollient derived from plant sources that softens skin and improves product texture.
Irritation
low
Source
semi-synthetic
A lightweight, plant-derived emollient that hydrates and smooths skin without clogging pores, ideal for sensitive and oily skin types.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived emollient that hydrates and softens skin without clogging pores, ideal for sensitive and oily skin types.
Irritation
low
Source
semi-synthetic
Isosorbide Oleate is a gentle, plant-derived emollient that softens skin and helps other ingredients absorb better, with a low risk of irritation or clogged pores.
Irritation
low
Source
semi-synthetic
Isostearamide DEA helps create rich lather and thick texture in cleansers, but it may cause mild irritation for sensitive skin.
Irritation
moderate
Source
synthetic
Isostearamide MEA is a mild synthetic ingredient that helps create rich lather and thicker textures in cleansers, but it offers no direct skin benefit beyond formulation.
Irritation
low
Source
synthetic
A mild synthetic thickener and conditioner that helps products feel creamy and rinse cleanly, but offers no active skincare benefits.
Irritation
low
Source
synthetic
A synthetic emulsifier that helps blend oil and water in creams and lotions, generally considered safe and low-irritation for most skin types.
Irritation
low
Source
synthetic
A gentle, foam-boosting surfactant that cleans effectively without stripping the skin barrier.
Irritation
low
Source
semi-synthetic
Conditioning Agent
Isostearamidopropyl Dimethylamine Gluconate
A mild, effective conditioning ingredient that improves hair feel and manageability without heavy buildup.
Irritation
low
Source
semi-synthetic
Conditioning Agent
ISOSTEARAMIDOPROPYL DIMETHYLAMINE GLYCOLATE
A gentle conditioning ingredient that helps detangle and soften hair without heavy buildup.
Irritation
low
Source
semi-synthetic
Hair Conditioning Agent
ISOSTEARAMIDOPROPYL DIMETHYLAMINE LACTATE
A gentle, effective conditioning ingredient that improves hair feel and detangling without heavy buildup.
Irritation
low
Source
semi-synthetic
Antistatic Agent
Isostearamidopropyl Epoxypropyl Dimonium Chloride
A synthetic conditioning ingredient that helps detangle hair and reduce static, but may not suit very sensitive scalps.
Irritation
low
Source
synthetic
Antistatic Agent
Isostearamidopropyl Epoxypropylmorpholinium Chloride
A synthetic conditioning agent that reduces static and improves hair feel, but has limited research on long-term skin effects.
Irritation
low
Source
synthetic
Antistatic Agent
Isostearamidopropyl Ethyldimonium Ethosulfate
A gentle synthetic conditioner that smooths hair and reduces static without heavy buildup.
Irritation
low
Source
synthetic
Antistatic Agent
Isostearamidopropyl Ethylmorpholinium Ethosulfate
A gentle synthetic conditioner that helps detangle and soften hair without heavy buildup.
Irritation
low
Source
synthetic
Antistatic Agent
Isostearamidopropyl Laurylacetodimonium Chloride
A gentle synthetic conditioner that smooths hair and reduces static, but may feel heavy on fine hair.
Irritation
low
Source
synthetic
A mild conditioning ingredient that helps reduce static and improve manageability in hair products, but is not a primary moisturizer.
Irritation
low
Source
synthetic
A synthetic conditioning agent that reduces static and improves feel in hair and skin products, generally well-tolerated but with limited research on long-term effects.
Irritation
low
Source
synthetic
A gentle surfactant that helps create a rich lather without stripping the skin.
Irritation
low
Source
synthetic
A gentle conditioning ingredient that helps hair feel soft and smooth without heavy buildup, but may not suit very fine or oily hair types.
Irritation
low
Source
synthetic
A gentle surfactant that adds foam and conditioning without stripping the skin or hair.
Irritation
low
Source
synthetic
A synthetic conditioning agent that reduces static and softens hair, but may cause irritation or clog pores in sensitive individuals.
Irritation
moderate
Source
synthetic
A gentle synthetic emulsifier that helps mix water and oil in creams and cleansers, with low irritation potential.
Irritation
low
Source
synthetic
A gentle synthetic emulsifier that helps create stable, creamy textures in skincare without common irritation.
Irritation
low
Source
synthetic