A gentle, lab-grown plant extract that may help calm skin and fight free radical damage, though research is still early.
Irritation
low
Source
biotech
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A gentle, lab-grown plant extract that may help calm skin and fight free radical damage, though research is still early.
Irritation
low
Source
biotech
A gentle botanical extract with antioxidant potential, but research is limited and benefits are not yet well-established.
Irritation
low
Source
natural
A gentle, antioxidant-rich oil from a rare plant, but research is very limited—use with realistic expectations.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant potential, but research is limited and benefits are not well-established in human skin.
Irritation
low
Source
natural
A gentle plant extract with antioxidant potential, but research on its specific skin benefits is still limited.
Irritation
low
Source
natural
A gentle, plant-derived water that may offer mild soothing and antioxidant benefits, but lacks strong clinical evidence.
Irritation
low
Source
natural
A synthetic fragrance compound that adds a tropical scent but offers no skincare benefits and may be unnecessary for sensitive skin.
Irritation
low
Source
synthetic
A gentle, antioxidant-rich plant ingredient from oxeye daisy cells that may help calm skin and fight free radical damage, though research is still early.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant and soothing potential, but research on its effectiveness in skincare is still limited.
Irritation
low
Source
natural
A gentle botanical extract that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
A gentle, fermented botanical extract with antioxidant potential, but research on its specific benefits is still limited.
Irritation
low
Source
natural
A modified beeswax that helps thicken and stabilize formulas, but may be slightly more comedogenic than regular beeswax.
Irritation
low
Source
natural
A plant-based film-former that helps create peel-off masks and absorb excess oil, but offers no active skincare benefits.
Irritation
low
Source
semi-synthetic
A natural wood extract with a warm, woody scent that may offer mild antimicrobial benefits, but can be irritating for sensitive skin.
Irritation
moderate
Source
natural
A synthetic polymer that helps products stay put and resist water, generally considered safe and non-irritating.
Irritation
low
Source
synthetic
Oxidized glutathione is a less active form of glutathione that may support skin brightening and antioxidant protection, but its effectiveness in topical products is still being studied.
Irritation
low
Source
natural
A gentle, antioxidant-rich fermented extract that helps calm and protect the skin with postbiotic benefits.
Irritation
low
Source
natural
A gentle, naturally derived emollient that helps soften and smooth skin with a low risk of irritation or clogged pores.
Irritation
low
Source
natural
A gentle, antioxidant-rich extract from lemongrass that may help soothe skin and fight free radicals, but research on the oxidized form is limited.
Irritation
low
Source
natural
A modified wax that helps give lipsticks and creams their smooth, solid texture, but may clog pores for some.
Irritation
low
Source
semi-synthetic
Oxidized patchouli leaf extract is a fragrant botanical ingredient used mainly for its scent, but it has limited research on skin benefits and may cause irritation in sensitive individuals.
Irritation
moderate
Source
natural
A gentle, plant-derived powder that helps control oil and improve product feel without clogging pores.
Irritation
low
Source
semi-synthetic
Antistatic Agent
Oxidized Starch Hydroxypropyltrimonium Chloride
A gentle, positively charged starch that helps hair feel soft and smooth while reducing static and flyaways.
Irritation
low
Source
semi-synthetic
A plant-based biotech ingredient with antioxidant potential, but research is still early and benefits are not yet proven in human studies.
Irritation
low
Source
biotech
A gentle botanical extract with antioxidant potential, but research is limited and benefits are not well-established.
Irritation
low
Source
natural
Skin conditioning agent
OXO AZAANDROSTENE CARBOXYLOYL DECAPEPTIDE-18
A synthetic peptide that may help firm and smooth skin by mimicking a hormone signal, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic UV filter that helps protect your skin from sun damage, but it's not a primary active in most products.
Irritation
low
Source
synthetic
A synthetic fragrance ingredient that adds a pleasant scent but offers no skincare benefits; safe for most at low concentrations.
Irritation
low
Source
synthetic
A synthetic ceramide mimic that helps reinforce the skin barrier and lock in moisture, ideal for dry or sensitive skin.
Irritation
low
Source
synthetic
A lab-made nucleotide that may help protect skin DNA from oxidative stress, but human skincare evidence is still limited.
Irritation
low
Source
synthetic
Oxosuccinic acid is a gentle alpha-keto acid exfoliant that may help brighten skin and support antioxidant defenses, but research is still emerging.
Irritation
moderate
Source
natural
A synthetic antioxidant that may help protect skin from environmental stress, but research is still limited.
Irritation
low
Source
synthetic
A promising antioxidant ingredient that helps your skin make its own glutathione, but research is still emerging compared to more established antioxidants like vitamin C.
Irritation
low
Source
synthetic
A gentle, plant-derived antioxidant that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
Oxygen in skincare is more about marketing than proven skin benefits; it may offer a temporary refreshing sensation but lacks strong evidence for lasting effects.
Irritation
low
Source
natural
A synthetic film-former that helps products stay put on skin and hair, but offers no active skincare benefit.
Irritation
low
Source
synthetic
Oxyquinoline is an effective preservative but may cause skin irritation in sensitive individuals; its use is restricted in some regions.
Irritation
moderate
Source
synthetic
Oxyquinoline benzoate is a synthetic preservative that helps keep products fresh, but it may cause skin irritation in sensitive individuals and is less common in modern formulations.
Irritation
moderate
Source
synthetic
Oxyquinoline Sulfate is a synthetic preservative that helps keep products fresh, but it can be irritating for sensitive skin and is less common in modern formulations.
Irritation
moderate
Source
synthetic
Oyster extract is a mineral-rich ingredient that may help hydrate and soothe skin, but research on its cosmetic benefits is still emerging.
Irritation
low
Source
natural
A gentle, hydrating ferment that may help soothe skin and support a healthy moisture barrier.
Irritation
low
Source
natural
A gentle, ocean-inspired extract that may help calm skin and fight free radicals, though research is still early.
Irritation
low
Source
natural
A gentle, natural exfoliant rich in calcium and trace minerals, best for those seeking a mild physical scrub without harsh microbeads.
Irritation
low
Source
natural
Oyster shell powder is a natural, mineral-rich exfoliant, but its sharp particles can be harsh on sensitive skin.
Irritation
moderate
Source
natural
Ozokerite is a reliable, low-irritation wax that helps keep your lipsticks and balms solid and smooth, but it's a petroleum-derived ingredient with no active skin benefits.
Irritation
low
Source
natural
Ozone is a powerful gas with antimicrobial potential, but its use in skincare is experimental and carries significant safety concerns due to its reactivity and instability.
Irritation
high
Source
synthetic
Ozonized argan oil combines the moisturizing benefits of argan oil with the purifying potential of ozone, but research on its cosmetic benefits is still emerging.
Irritation
low
Source
semi-synthetic
A unique oil that combines castor oil's moisturizing power with ozone's potential antimicrobial benefits, but research is still early.
Irritation
low
Source
semi-synthetic
Ozonized glycerin is a gentle, multi-tasking ingredient that hydrates while offering soothing and antimicrobial benefits, making it a promising option for acne-prone or sensitive skin.
Irritation
low
Source
semi-synthetic
Ozonized jojoba oil combines the moisturizing benefits of jojoba with the antimicrobial potential of ozone, but research on its cosmetic efficacy is still limited.
Irritation
low
Source
semi-synthetic
Ozonized macadamia seed oil is a gentle, oxygen-enriched emollient that may support skin comfort and barrier function, but its ozone-related benefits are still being explored.
Irritation
low
Source
semi-synthetic
Ozonized meadowfoam seed oil is a unique, oxygen-enriched oil that may help calm skin and support a clearer complexion, though research is still emerging.
Irritation
low
Source
semi-synthetic
Ozonized Oleth-10 is a semi-synthetic surfactant with added ozone for potential antimicrobial benefits, but its skin effects are not well-studied and it may be drying for sensitive skin.
Irritation
moderate
Source
semi-synthetic
Ozonized PEG-10 Oleate is a semi-synthetic cleansing agent that helps remove dirt and oil, but its ozonized form is less studied and may cause irritation for sensitive skin.
Irritation
moderate
Source
semi-synthetic
A mild emulsifier that helps blend oil and water in cleansers, with added ozonized fatty acids for potential skin-soothing benefits.
Irritation
low
Source
semi-synthetic
Antioxidant
Ozonized Pereskia Grandifolia Callus Culture Extract
A novel, lab-grown plant extract with antioxidant potential, but research is still early and benefits are not yet proven in human studies.
Irritation
low
Source
biotech
Ozonized Polysorbate 80 is a modified emulsifier with potential antimicrobial benefits, but its ozone content may cause irritation for sensitive skin.
Irritation
moderate
Source
semi-synthetic
A novel biotech ingredient with antioxidant potential, but research is very limited and it's rarely found in mainstream products.
Irritation
low
Source
biotech
A novel biotech ingredient that combines rice callus extract with ozone for antioxidant and soothing benefits, but research is still emerging.
Irritation
low
Source
biotech
Ozonized sesame seed oil is a unique ingredient that combines the moisturizing benefits of sesame oil with the purifying properties of ozone, making it a promising option for acne-prone or irritated skin.
Irritation
low
Source
semi-synthetic