Ingredient review
Ozonized Rice Callus Extract
INCI: OZONIZED ORYZA SATIVA CALLUS CULTURE EXTRACT
A novel biotech ingredient that combines rice callus extract with ozone for antioxidant and soothing benefits, but research is still emerging.
In plain English
This ingredient is made by growing rice cells in a lab (callus culture) and then treating them with ozone gas. The process creates compounds that may help calm irritated skin and protect it from environmental damage. It's a high-tech, sustainable alternative to traditional plant extracts.
Review score
Safety, usefulness, and evidence
Potentially useful with some tradeoffs
The evidence base is still emerging, so marketing claims deserve extra caution.
Risk flags are low for most users, though the finished product can still irritate.
- Source
- biotech
- Evidence
- emerging
- Irritation
- low
- Clogging risk
- low
Quick decision guide
Useful, but context matters
Ozonized Rice Callus Extract is generally a lower-concern ingredient when the full formula suits your skin.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Ozonized Rice Callus Extract.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
lowLess likely to sting, burn, or bother most users, though sensitive skin can still react.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
emergingThe ingredient may be promising, but claims should be treated more cautiously.
What it is
Ozonized Oryza Sativa Callus Culture Extract is a biotech-derived ingredient produced by cultivating rice callus cells in a controlled environment and then exposing them to ozone. This process is thought to enhance the antioxidant and soothing properties of the extract.
How it works
In a cosmetic product, this ingredient is believed to work by delivering antioxidant compounds that neutralize free radicals, and by providing soothing effects that can reduce redness and irritation. The ozonation step may create unique bioactive molecules that support skin health.
Pros
Sustainable production
Made from lab-grown rice cells, reducing the need for agricultural land and water, and offering a consistent, pure ingredient.
Gentle on skin
Low irritation and comedogenic risk makes it suitable for sensitive and acne-prone skin types.
Cons and cautions
Limited research
There are few peer-reviewed studies on this specific ingredient, so its benefits are based on theoretical mechanisms rather than robust clinical data.
Higher cost
The biotech production process is more expensive than traditional plant extraction, which may be reflected in product pricing.
Best for
- People with sensitive or easily irritated skin
- Those looking for antioxidant protection from a sustainable source
Use caution if
- Individuals with known allergies to rice or rice-derived ingredients
- Those seeking ingredients with extensive clinical backing
Usage tips
Safety summary
Ozonized Rice Callus Extract is considered safe for topical use with low irritation and comedogenic potential. However, due to limited research, those with rice allergies should exercise caution.
Research notes
Research on ozonized plant extracts in general suggests antioxidant and antimicrobial properties, but specific studies on this rice callus extract are scarce. Most evidence is theoretical or from related ingredients.
Common label clues
- Typical concentration
- Typically used at 0.1% to 2% in leave-on products
- Regulatory status
- Generally recognized as safe for cosmetic use in the EU and US, but specific ozonized ingredients may require additional safety data depending on concentration.
- Common uses
- Serums, Moisturizers, Anti-aging creams
- Environmental note
- The biotech production method is more sustainable than traditional farming, using less water and land, and avoiding pesticides.
Good to know
- Ozonization is a process that can create new compounds with unique properties, but the exact composition of this extract can vary between manufacturers.
- Rice callus culture is a form of plant biotechnology that allows for year-round production without seasonal limitations.
Common questions
What is Ozonized Rice Callus Extract in beauty products?
This ingredient is made by growing rice cells in a lab (callus culture) and then treating them with ozone gas. The process creates compounds that may help calm irritated skin and protect it from environmental damage. It's a high-tech, sustainable alternative to traditional plant extracts.
What does Ozonized Rice Callus Extract do in a beauty product?
In a cosmetic product, this ingredient is believed to work by delivering antioxidant compounds that neutralize free radicals, and by providing soothing effects that can reduce redness and irritation. The ozonation step may create unique bioactive molecules that support skin health.
Is Ozonized Rice Callus Extract safe for most people?
Ozonized Rice Callus Extract is considered safe for topical use with low irritation and comedogenic potential. However, due to limited research, those with rice allergies should exercise caution.
Who should be careful with Ozonized Rice Callus Extract?
Individuals with known allergies to rice or rice-derived ingredients Those seeking ingredients with extensive clinical backing
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.