MDM Hydantoin is an effective preservative but may irritate sensitive skin due to its slow release of formaldehyde.
Irritation
moderate
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
MDM Hydantoin is an effective preservative but may irritate sensitive skin due to its slow release of formaldehyde.
Irritation
moderate
Source
synthetic
A synthetic preservative that helps keep products fresh but may cause irritation in sensitive skin.
Irritation
moderate
Source
synthetic
MEA-Benzoate is a synthetic preservative helper that extends shelf life but may cause irritation for sensitive skin.
Irritation
moderate
Source
synthetic
A synthetic preservative with limited public research; generally considered safe at low concentrations but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Methenamine is a synthetic preservative that works by slowly releasing formaldehyde, which can be effective but raises concerns for skin sensitivity and long-term safety.
Irritation
moderate
Source
synthetic
Methenammonium Chloride is a synthetic preservative that helps keep products fresh but may cause irritation in sensitive skin.
Irritation
moderate
Source
synthetic
A synthetic solvent and preservative that helps products stay fresh but may cause irritation for sensitive skin.
Irritation
moderate
Source
synthetic
Methyl 2,6-dihydroxybenzoate is a synthetic fragrance and preservative helper that can be irritating for sensitive skin.
Irritation
moderate
Source
synthetic
A synthetic preservative helper that keeps products fresh and stable, but it's not a star active ingredient for your skin.
Irritation
low
Source
synthetic
A gentle preservative booster and fragrance component that helps keep products fresh, but may cause mild irritation in very sensitive skin.
Irritation
low
Source
synthetic
A powerful preservative that is a common contact allergen; best avoided by those with sensitive skin.
Irritation
high
Source
synthetic
Methylene glycol is a controversial preservative that releases formaldehyde; it is effective but can cause irritation and is best avoided by sensitive individuals.
Irritation
high
Source
synthetic
A powerful but controversial preservative that is a common allergen; many prefer to avoid it.
Irritation
high
Source
synthetic
Methylparaben is an effective, low-irritation preservative, but some consumers avoid it due to concerns about endocrine disruption.
Irritation
low
Source
synthetic
An effective preservative and antistatic agent, but can be irritating to sensitive skin or eyes at higher concentrations.
Irritation
moderate
Source
synthetic
An effective preservative but can be irritating for sensitive skin at higher concentrations.
Irritation
moderate
Source
synthetic
Natamycin is a gentle, naturally derived preservative that fights fungi and yeast, making it a good option for sensitive skin formulas.
Irritation
low
Source
natural
Nisin is a gentle, naturally derived preservative that helps keep skincare products fresh while supporting a healthy skin microbiome.
Irritation
low
Source
natural
A gentle synthetic preservative that helps keep your skincare products fresh and safe without common irritation.
Irritation
low
Source
synthetic
O-Tolyl Biguanide is an effective preservative but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Octylisothiazolinone is an effective preservative but can be a skin sensitizer, so it's mainly restricted to rinse-off formulas.
Irritation
moderate
Source
synthetic
Ortho-phenylphenol is a synthetic preservative that is effective but carries moderate irritation and regulatory restrictions, especially for leave-on products.
Irritation
moderate
Source
synthetic
Oxyquinoline is an effective preservative but may cause skin irritation in sensitive individuals; its use is restricted in some regions.
Irritation
moderate
Source
synthetic
Oxyquinoline benzoate is a synthetic preservative that helps keep products fresh, but it may cause skin irritation in sensitive individuals and is less common in modern formulations.
Irritation
moderate
Source
synthetic
Oxyquinoline Sulfate is a synthetic preservative that helps keep products fresh, but it can be irritating for sensitive skin and is less common in modern formulations.
Irritation
moderate
Source
synthetic
p-Anisic acid is a mild, naturally derived preservative helper that also offers gentle antioxidant and soothing benefits, making it a safe choice for most skin types.
Irritation
low
Source
natural
P-Cresol is a synthetic fragrance and preservative compound that can be irritating; it is rarely used in modern leave-on skincare and is best avoided by sensitive skin.
Irritation
moderate
Source
synthetic
p-Isopropylphenol is a synthetic preservative that helps keep products fresh, but it may cause irritation for sensitive skin types.
Irritation
moderate
Source
synthetic
Parabens are effective, low-irritation preservatives, but consumer concerns about potential endocrine disruption have led many brands to seek alternatives.
Irritation
low
Source
synthetic
Preservative
Methylparaben, Propylparaben, Butylparaben, Ethylparaben
Parabens are effective preservatives with a long safety record, but concerns about hormone disruption have led many to seek paraben-free alternatives.
Irritation
low
Source
synthetic
A synthetic preservative booster that helps prevent microbial growth but may cause irritation for sensitive skin.
Irritation
moderate
Source
synthetic
A paraben-based preservative that is effective but controversial due to paraben safety concerns.
Irritation
moderate
Source
synthetic
Phenoxyacetic acid is a synthetic ingredient used to boost preservative systems and adjust pH, but it is less common than alternatives like phenoxyethanol.
Irritation
low
Source
synthetic
Phenoxyethanol is a safe and effective preservative that keeps your products fresh and free from harmful bacteria.
Irritation
low
Source
synthetic
Phenoxyethylparaben is a paraben preservative that is rarely used today because of consumer concerns and regulatory restrictions in some regions.
Irritation
low
Source
synthetic
Phenoxyisopropanol is a less common synthetic preservative that helps keep products fresh, but it has limited safety data compared to alternatives like phenoxyethanol.
Irritation
low
Source
synthetic
A gentle preservative booster and humectant that helps keep formulas fresh and hydrated without common irritation.
Irritation
low
Source
synthetic
A synthetic enzyme blocker that helps preserve active ingredients but may cause irritation at higher concentrations.
Irritation
moderate
Source
synthetic
Phenylparaben is a synthetic preservative that is effective but controversial due to potential endocrine-disrupting concerns; it is now rarely used in modern skincare.
Irritation
moderate
Source
synthetic
Phenylpentanol is a gentle synthetic ingredient that helps preserve products and lightly conditions skin, making it a safer alternative to harsher preservatives.
Irritation
low
Source
synthetic
Phthalates are controversial synthetic chemicals linked to endocrine disruption; most are banned or restricted in cosmetics in many regions, but consumers should still check labels for hidden sources.
Irritation
low
Source
synthetic
An effective, low-irritation preservative that helps keep your products safe from germs, but has faced some regulatory scrutiny in Europe.
Irritation
low
Source
synthetic
A gentle, naturally-derived preservative booster that helps keep your skincare products fresh without harsh chemicals.
Irritation
low
Source
biotech
A gentle, fermentation-derived preservative booster that helps keep products fresh without harsh chemicals.
Irritation
low
Source
biotech
A synthetic preservative booster that helps keep products fresh, but may cause irritation for sensitive skin.
Irritation
moderate
Source
synthetic
Potassium Acetate is a safe, low-irritation salt that helps control a product's pH and can support preservative systems.
Irritation
low
Source
synthetic
A gentle, widely used preservative that helps keep your products safe from bacteria and mold without common irritation.
Irritation
low
Source
synthetic
Potassium borate is a synthetic salt used to adjust pH and preserve products, but it raises safety concerns due to its boron content and potential for irritation.
Irritation
moderate
Source
synthetic
Potassium bromide is a synthetic salt used as a preservative, but it has limited cosmetic use and potential irritation concerns.
Irritation
moderate
Source
synthetic
A paraben preservative that is effective but controversial due to potential endocrine concerns; many brands now avoid it.
Irritation
low
Source
synthetic
A paraben preservative that is effective against microbes but has raised some safety concerns in certain consumer circles.
Irritation
low
Source
synthetic
Potassium iodide is a safe preservative helper in tiny amounts, but it is not a skin-beneficial active and may be unnecessary in well-formulated products.
Irritation
low
Source
synthetic
Potassium Metabisulfite is an effective preservative but can be a common allergen, especially for those with sulfite sensitivity.
Irritation
moderate
Source
synthetic
A widely used preservative that prevents microbial growth, but has raised some safety concerns regarding potential endocrine disruption.
Irritation
low
Source
synthetic
A synthetic preservative that helps keep products fresh but may cause irritation for sensitive skin at higher concentrations.
Irritation
moderate
Source
synthetic
A mild, well-tolerated preservative that helps keep your skincare products fresh and safe from spoilage.
Irritation
low
Source
synthetic
Potassium Paraben is an effective preservative but has raised concerns about potential endocrine disruption, leading many brands to phase it out.
Irritation
low
Source
synthetic
Potassium Phenoxide is a synthetic preservative booster that helps keep products fresh, but may cause irritation in sensitive individuals at higher concentrations.
Irritation
moderate
Source
synthetic
Potassium Propionate is a mild preservative that helps keep products fresh and stable, but it is not as widely studied as some alternatives.
Irritation
low
Source
synthetic
Potassium propylparaben is an effective preservative but has raised concerns about potential endocrine disruption, leading many brands to phase it out.
Irritation
low
Source
synthetic