Beauty ingredient research

Beauty ingredients explained in plain English

Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.

20769

Reviewed ingredients

524

Low-concern standouts

2884

Need usage caution

Showing 34 of 94
AllUV absorberUV filterabrasiveabsorbentacne treatmentactiveactive ingredientadhesivealkalizing agentamino acidanti-aginganti-androgenanti-cavityanti-cavity agentanti-inflammatoryanti-irritantanticariesanticavity agentantidandruffantifungalantimicrobialantioxidantantiperspirantantiplaqueastringentbarrier repairbarrier supportbarrier-repairbarrier-supportbinderbinding agentbiotechbiotechnologybond-builderbotanicalbotanical extractbotanical oilbotanical waterbrighteningbrightening agentbufferbuffering agentcell-communicating ingredientceramidechelating agentchemicalchemical intermediateclaycleansercleansingcleansing agentcolorantconditionerconditioningconditioning agentcooling agentcosmeticcosmetic additivecosmetic colorantcosmetic ingredientcosmetic pigmentcosmetic powdercosmetic-texturizercosmetic-waxcosmeticscrosslinking agentdelivery agentdelivery systemdenaturantdeodorantdeodorant agentdepigmenting agentdepilatorydepilatory agentdesensitizing agentdyedye intermediatedye precursordye-intermediateemollientemulsifierenzymeessential oilexfoliantexperimentaleyelashfermentfilm formerfilm-formerfilm-formingfilm-forming agentfirming agentfixativeflavoring agentformulationfragrancefragrance ingredientfunctional ingredientgashair carehair colorhair coloranthair conditionerhair dyehair removalhair-carehair-colorhaircarehumectantindustrialinsecticideintermediatelashlash carelash enhancerlash-and-browlip carelipidmakeupmarine extractmasking agentmicrobiomemicrobiome modulatormineralmoisturizernail carenail-careocclusiveoilopacifieropacifying agentoptical agentoral careotheroxidative dyeoxidative dye precursoroxidizing agentpH adjusterpain reliefpenetration enhancerpeptidepersonal careph adjusterpharmaceuticalpheromonepigmentplant oilplasticizerpolymerpolymer precursorprebioticprescription-drugpreservativepreservative boosterprobioticprocessing agentprocessing aidpropellantproteinpurifyingreducing agentretinoidscalp caresebum regulatorsebum-regulatorself-tannerself-tanningsensory additivesensory agentsensory modifiersiliconeskin barrierskin barrier supportskin conditionerskin conditioningskin conditioning agentskin lighteningskin protectantskin-conditioningskin-conditioning agentskin-identicalskin-identical ingredientskin-lighteningskin-lightening agentskincaresolventsoothingsoothing agentstabilizerstimulantsunscreensurfactantsyntheticsynthetic colorantsynthetic dyesynthetic resinsynthetic-coloranttexture enhancertexturizerthickenertoneruv-absorberuv-filtervasoactivevasodilatorviscosity controlviscosity controllingviscosity controlling agentvitaminwax

Delivery Enhancer

Phosphorothioate RNA-2 Cholesterol

SH-DS PHOSPHOROTHIOATE RNA-2 CHOLESTEROL

3.0

An experimental, cholesterol-linked RNA ingredient with potential for targeted skin delivery, but lacks broad safety and efficacy data for cosmetic use.

Irritation

moderate

Source

synthetic

beautyskincareactive
Read ingredient review

Antioxidant

Phytoglobin

Phytoglobin

3.8

Phytoglobin is a plant-based protein that may help boost skin oxygenation and radiance, but research is still emerging and it's not a proven substitute for clinical treatments.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Skin-conditioning agent

Pichia Retinol Ferment

Pichia/Retinol Ferment Extract

4.0

A gentler, fermented form of retinol that may support smoother, brighter skin with less irritation than traditional retinol.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Penetration enhancer

Piperine

Piperine

3.5

Piperine may boost ingredient absorption but can be irritating; it's not a common or well-studied skincare ingredient on its own.

Irritation

moderate

Source

natural

beautyskincareactive
Read ingredient review

Skin conditioning agent

Porcine Cell Conditioned Media

Pig Dental Pulp Cell/Adipocyte/Bone Marrow Cell Conditioned Media

2.5

An experimental biotech ingredient from pig cells with limited human research and ethical concerns; not recommended for routine use.

Irritation

moderate

Source

biotech

beautyskincareactive
Read ingredient review

Anti-hair loss agent

Pyrrolidinyl Diaminopyrimidine Oxide

PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE

3.8

A synthetic ingredient that may help slow hair thinning by reducing collagen buildup around hair follicles, but results vary and it works best as part of a comprehensive hair care routine.

Irritation

low

Source

synthetic

beautyhaircareactive
Read ingredient review

Skin conditioning

Red Junglefowl Stem Cell Culture

RED JUNGLEFOWL BLASTODERM PLURIPOTENT CELL CULTURE CONDITIONED MEDIA

3.5

A novel biotech ingredient from bird stem cells that may support skin repair, but human research is very limited.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Cell-communicating ingredient

Retinol

Retinol

4.5

Retinol is a gold-standard anti-aging ingredient that speeds up skin renewal but can cause irritation if not introduced gradually.

Irritation

moderate

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Cell-communicating ingredient

Retinol Yeast Ferment Complex

Retinol, Saccharomyces Polypeptide

4.0

A retinol-peptide hybrid that aims to smooth fine lines and improve texture with a gentler touch than plain retinol.

Irritation

moderate

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Anti-aging agent

Retinyl Dimethylglycylprolinate

RETINYL DIMETHYLGLYCYLPROLINATE

4.0

A next-generation retinoid that aims to smooth wrinkles and improve skin texture with a gentler touch than standard retinol.

Irritation

low

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Anti-aging agent

Retinyl Methoxy PEG-22 Acetate

Retinyl Methoxy PEG-22 Acetate

3.8

A gentle, water-soluble retinoid that offers anti-aging benefits with less irritation than traditional retinol.

Irritation

low

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Anti-aging agent

SH-Polypeptide-106

SH-Polypeptide-106

4.0

A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but human data is still limited.

Irritation

low

Source

synthetic

beautyskincareactive
Read ingredient review

Anti-aging agent

SH-Polypeptide-45

SH-Polypeptide-45

3.8

SH-Polypeptide-45 is a lab-made peptide that may help support firmer-looking skin, but research is still early and results vary.

Irritation

low

Source

synthetic

beautyskincareactive
Read ingredient review

Anti-aging agent

SH-Polypeptide-69

SH-Polypeptide-69

3.8

SH-Polypeptide-69 is a lab-made peptide that may help signal skin to produce more collagen, but research is still early and results vary.

Irritation

low

Source

synthetic

beautyskincareactive
Read ingredient review

Anti-Aging Agent

SH-Polypeptide-82

SH-Polypeptide-82

3.8

A lab-made peptide that may help support collagen and improve skin firmness, but research is still early and results vary.

Irritation

low

Source

synthetic

beautyskincareactive
Read ingredient review

Skin conditioning

Sheep Dermal Cell Lysate

SHEEP DERMAL CELLS LYSATE

3.5

A novel biotech ingredient that may support skin repair, but human evidence is still limited.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Skin-conditioning agent

Shikimate Retinyl Ester

Retinyl Hydroxypentanoatyl Shikimate

4.0

A next-generation retinoid designed to deliver anti-aging benefits with less irritation than traditional retinol.

Irritation

low

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Skin conditioning agent

Stem Cell Conditioned Media

Immortalized Human Tooth Pulp Stem Cell Conditioned Media

3.0

A novel biotech ingredient with promising lab research but very limited human studies; best viewed as a luxury novelty rather than a proven essential.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Firming agent

Synephrine

SYNEPHRINE

3.0

Synephrine may offer temporary skin firming effects, but evidence is limited and it can cause irritation, especially at higher concentrations.

Irritation

moderate

Source

natural

beautyskincareactive
Read ingredient review

Skin-conditioning agent

Synephrine HCL

SYNEPHRINE HCL

2.5

Synephrine HCL is a synthetic ingredient sometimes added to cosmetics for a temporary tightening sensation, but its effectiveness and safety for topical use are not well-established.

Irritation

moderate

Source

synthetic

beautyskincareactive
Read ingredient review

Cell-communicating ingredient

Tazarotene

TAZAROTENE

4.0

Tazarotene is a potent prescription retinoid that effectively treats acne and reduces fine lines, but it requires careful use due to high irritation potential.

Irritation

high

Source

synthetic

beautyskincareactive
Read ingredient review

Hair growth stimulant

Tetraaminopyrimidine Sulfate

TETRAAMINOPYRIMIDINE SULFATE

3.8

A synthetic ingredient that may help reduce hair shedding and support thicker-looking hair, but evidence is still building.

Irritation

low

Source

synthetic

beautyhaircareactive
Read ingredient review

Anti-Wrinkle Agent

Tetramethyl Pyrazolylpyrimidine HCl

TETRAMETHYL PYRAZOLYLPYRIMIDINE HCL

3.8

A synthetic compound that may help soften expression lines by relaxing facial muscles, but research is still limited compared to more established ingredients.

Irritation

low

Source

synthetic

beautyskincareactive
Read ingredient review

Firming agent

Theophylline

THEOPHYLLINE

3.5

Theophylline may temporarily tighten skin and improve circulation, but results are modest and it can cause irritation for sensitive skin.

Irritation

moderate

Source

synthetic

beautyskincareactive
Read ingredient review

Skin conditioning agent

Thymidine

Thymidine

4.0

Thymidine is a gentle, science-backed ingredient that helps support skin’s natural repair processes, making it a smart addition to anti-aging and recovery routines.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Conditioning Agent

Tooth Pulp Stem Cell Conditioned Media

Human Tooth Pulp Stem Cell Conditioned Media

2.5

An exotic, high-tech ingredient with very limited human research; its benefits are largely theoretical and not proven in everyday skincare.

Irritation

low

Source

biotech

beautyskincareactive
Read ingredient review

Cell-communicating ingredient

Tretinoin

TRETINOIN

4.5

A powerful prescription retinoid that effectively treats acne and reduces signs of aging, but requires careful use due to high irritation potential.

Irritation

high

Source

synthetic

beautyskincareactive
Read ingredient review

Cell-communicating ingredient

Triacetyl Retinoyl Phytosphingosine

Triacetyl Retinoyl Phytosphingosine

4.0

A gentle, next-generation retinoid alternative that pairs vitamin A activity with skin-identical lipid support, but clinical evidence is still limited.

Irritation

low

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Photosensitizer

Trisodium Chlorin E6

Trisodium Chlorin E6

3.0

Trisodium Chlorin E6 is a light-activated compound used in professional treatments, not a daily skincare ingredient.

Irritation

moderate

Source

semi-synthetic

beautyskincareactive
Read ingredient review

Skin conditioning

Wild Boar Platelet Extract

Wild Boar Platelet Extract

3.0

An exotic, animal-derived ingredient with potential skin-repair benefits but limited human research and ethical concerns.

Irritation

moderate

Source

natural

beautyskincareactive
Read ingredient review

Anti-Aging Agent

Zinc Retinoate Hydroxide

ZINC RETINOATE HYDROXIDE

4.0

A gentler retinoid that aims to give you the anti-aging perks of retinoic acid with less redness and peeling.

Irritation

low

Source

semi-synthetic

beautyskincareactive
Read ingredient review