A potent enzyme that dissolves collagen, used sparingly in skincare for deep exfoliation, but requires caution due to its strength.
Irritation
moderate
Source
biotech
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A potent enzyme that dissolves collagen, used sparingly in skincare for deep exfoliation, but requires caution due to its strength.
Irritation
moderate
Source
biotech
Clotrimazole is a proven antifungal ingredient used in medicated products, not a routine cosmetic ingredient for healthy skin.
Irritation
moderate
Source
synthetic
A gentle, antioxidant-rich plant stem cell extract that may help protect skin from environmental stress, though human studies are limited.
Irritation
low
Source
biotech
Cloudberry fruit extract is a gentle, antioxidant-rich ingredient that helps protect skin from environmental stress and may support a more even complexion.
Irritation
low
Source
natural
Cloudberry juice is a gentle, antioxidant-rich fruit extract that helps protect skin from environmental stress and provides light hydration.
Irritation
low
Source
natural
Cloudberry Seed Extract is a gentle, antioxidant-rich ingredient that helps protect skin from environmental stress while providing light hydration and soothing benefits.
Irritation
low
Source
natural
Cloudberry seed oil is a lightweight, antioxidant-rich oil that helps nourish and protect the skin without clogging pores.
Irritation
low
Source
natural
Clove bark extract offers antioxidant benefits but can be irritating for sensitive skin at high concentrations.
Irritation
moderate
Source
natural
Clove Basil Oil adds a fresh, herbal scent and may help fight acne-causing bacteria, but it can be irritating for sensitive skin.
Irritation
moderate
Source
natural
Clove bud powder offers gentle physical exfoliation and a warm, spicy scent, but can be irritating for sensitive skin due to its eugenol content.
Irritation
moderate
Source
natural
Clove Bud Water adds a warm, spicy scent to products and may offer mild antioxidant benefits, but its fragrance can be irritating for sensitive skin.
Irritation
moderate
Source
natural
Clove extract offers antioxidant benefits but can be irritating for sensitive skin due to its high eugenol content.
Irritation
moderate
Source
natural
Clove Flower Oil offers antimicrobial and antioxidant benefits but is highly irritating and sensitizing, making it risky for most skincare routines.
Irritation
high
Source
natural
Clove leaf extract offers antioxidant and soothing benefits but can be irritating for sensitive skin at higher concentrations.
Irritation
moderate
Source
natural
Clove leaf oil can add a warm, spicy scent and mild antimicrobial benefits, but it is a known skin sensitizer and should be used with caution, especially at high concentrations.
Irritation
moderate
Source
natural
Clove oil can help fight acne-causing bacteria, but it is very potent and can easily irritate or burn skin if used undiluted.
Irritation
high
Source
natural
Clove Seed Extract offers antioxidant benefits but can be irritating for sensitive skin due to its high eugenol content.
Irritation
moderate
Source
natural
A natural antioxidant extract from clove stems that may help protect skin from environmental stress, but can be irritating for sensitive skin.
Irritation
moderate
Source
natural
Clove stem oil can add fragrance and antimicrobial benefits to skincare, but its high eugenol content makes it a common skin irritant and allergen.
Irritation
moderate
Source
natural
Antioxidant
Trifolium Pratense (Clover) Sprout Extract / Vigna Radiata (Mung Bean) Sprout Extract
A gentle, plant-based antioxidant blend that may help calm skin and defend against environmental stress, though research is still emerging.
Irritation
low
Source
natural
A lab-grown plant extract that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
biotech
A gentle botanical extract with antioxidant and soothing potential, but research is still emerging and benefits are not yet proven in large human studies.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant potential, but research in cosmetics is still limited.
Irritation
low
Source
natural
A gentle, water-based botanical extract with traditional use for soothing skin, though modern research is still emerging.
Irritation
low
Source
natural
A gentle botanical powder that may help calm redness and provide antioxidant protection, but human skin research is still limited.
Irritation
low
Source
natural
Cobalt Acetylmethionate is a synthetic ingredient that may offer antioxidant benefits, but its use is limited by safety concerns and a lack of robust human studies.
Irritation
moderate
Source
synthetic
A safe, stable blue pigment for color cosmetics, but those with cobalt sensitivity should check labels.
Irritation
low
Source
synthetic
Cobalt Aluminum Oxide is a safe, stable blue pigment for cosmetics, but it's not a skincare active and offers no skin benefits beyond color.
Irritation
low
Source
synthetic
A safe, stable pigment for color cosmetics, but not a skincare active and offers no skin benefits beyond color.
Irritation
low
Source
synthetic
Cobamamide is a gentle, active form of vitamin B12 that may help calm redness and support skin repair, but research in topical skincare is still limited.
Irritation
low
Source
biotech
A gentle marine ferment that helps hydrate and support the skin barrier, but research is still early.
Irritation
low
Source
biotech
A biotech marine ingredient that mimics the skin's natural moisture-holding molecules, offering gentle hydration and a plumping effect.
Irritation
low
Source
biotech
Cocamide helps create rich lather in cleansers but may be drying or irritating for sensitive skin.
Irritation
moderate
Source
natural
Cocamide DEA is an effective foaming agent, but its potential to form carcinogenic impurities and cause skin irritation makes it a controversial choice in modern formulations.
Irritation
moderate
Source
semi-synthetic
Cocamide DIPA helps create rich lather and thick texture in cleansers, but may be slightly drying for sensitive skin.
Irritation
moderate
Source
semi-synthetic
Cocamide MEA is an effective foam booster and thickener, but it can be mildly irritating for sensitive skin and has raised some environmental concerns.
Irritation
moderate
Source
semi-synthetic
A coconut-derived foaming agent that helps cleansers lather and feel thicker, but may be drying or irritating for sensitive skin.
Irritation
moderate
Source
semi-synthetic
Cocamide MIPA is a coconut-derived ingredient that helps create rich lather, but it may be mildly irritating for sensitive skin.
Irritation
moderate
Source
semi-synthetic
A gentle, coconut-derived cleansing agent that helps create a rich lather without stripping the skin.
Irritation
low
Source
semi-synthetic
A gentle, coconut-derived conditioning agent that helps reduce frizz and static without stripping the skin or hair.
Irritation
low
Source
semi-synthetic
A gentle, coconut-derived foaming agent that helps cleansers feel less stripping, though a small number of people may react to impurities.
Irritation
low
Source
semi-synthetic
Conditioning Agent
Cocamidopropyl Dimethylamine Dihydroxymethylpropionate
A gentle, coconut-derived conditioning ingredient that softens hair and skin without heavy buildup.
Irritation
low
Source
semi-synthetic
Conditioning Agent
Cocamidopropyl Dimethylamine Hydrolyzed Collagen
A gentle conditioning ingredient that helps soften hair and skin, but may cause irritation for sensitive scalps.
Irritation
moderate
Source
semi-synthetic
A gentle, coconut-derived conditioning agent that softens hair and skin without heavy buildup.
Irritation
low
Source
semi-synthetic
A gentle, coconut-derived conditioning agent that helps soften hair and skin without stripping natural oils.
Irritation
low
Source
semi-synthetic
Hair Conditioning Agent
COCAMIDOPROPYL DIMETHYLAMINOHYDROXYPROPYL HYDROLYZED COLLAGEN
A gentle conditioning ingredient that combines collagen's moisturizing benefits with mild cleansing properties, but its complex name can be misleading.
Irritation
low
Source
semi-synthetic
Surfactant
COCAMIDOPROPYL DIMETHYLAMMONIUM C8-16 ISOALKYLSUCCINYL LACTOGLOBULIN SULFONATE
A gentle conditioning surfactant that cleanses without stripping, but its complex structure means limited independent safety data.
Irritation
moderate
Source
semi-synthetic
Conditioning Agent
COCAMIDOPROPYLDIMONIUM HYDROXYPROPYL HYDROLYZED COLLAGEN
A gentle conditioning ingredient that helps detangle hair and soften skin without heavy buildup.
Irritation
low
Source
semi-synthetic
A mild, coconut-derived conditioner that helps detangle and soften hair without heavy buildup.
Irritation
low
Source
semi-synthetic
A gentle, coconut-derived cleanser that creates rich foam without stripping the skin.
Irritation
low
Source
semi-synthetic
Cocamidopropyl Morpholine is an effective emulsifier and surfactant, but may cause irritation for sensitive skin types, especially in high concentrations.
Irritation
moderate
Source
semi-synthetic
A mild surfactant that helps create rich foam and leaves skin feeling soft, but may cause irritation for sensitive skin.
Irritation
moderate
Source
semi-synthetic
A gentle, coconut-derived conditioning ingredient that helps detangle and soften hair without heavy buildup.
Irritation
low
Source
semi-synthetic
Surfactant
SODIUM COCAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE
A gentle, coconut-derived conditioning agent that helps reduce static and improve hair softness without heavy buildup.
Irritation
low
Source
semi-synthetic
A gentle conditioning ingredient that reduces static and improves hair manageability, but may cause mild irritation in sensitive individuals.
Irritation
low
Source
semi-synthetic
Hair Conditioner
Cocamidopropyltrimonium Dimethicone PEG-8 Succinate
A gentle silicone-based conditioner that smooths hair and reduces frizz without heavy buildup, but may not suit very fine or low-porosity hair.
Irritation
low
Source
semi-synthetic
A gentle, coconut-derived surfactant that helps create a rich lather and is less stripping than harsher cleansers.
Irritation
low
Source
natural
A gentle, coconut-derived surfactant that cleanses without stripping the skin barrier, suitable for sensitive skin.
Irritation
low
Source
semi-synthetic
A gentle, coconut-derived cleanser that effectively removes dirt and oil without stripping the skin, making it ideal for sensitive or dry skin types.
Irritation
low
Source
natural
A gentle, antioxidant-rich fruit extract that may help calm skin and protect against environmental stress, though research in cosmetics is still emerging.
Irritation
low
Source
natural