A protein extract from animal trachea that may help hydrate and temporarily smooth skin, but lacks strong independent research and may not suit vegans or those avoiding animal-derived ingredients.
Irritation
low
Source
natural
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A protein extract from animal trachea that may help hydrate and temporarily smooth skin, but lacks strong independent research and may not suit vegans or those avoiding animal-derived ingredients.
Irritation
low
Source
natural
A well-tolerated brightener that targets stubborn dark spots and melasma without the irritation of stronger alternatives.
Irritation
low
Source
synthetic
A gentle peptide that may help calm redness and support skin barrier comfort, though human studies are still limited.
Irritation
low
Source
synthetic
A newer peptide that aims to brighten skin by blocking the chain reaction that leads to dark spots, but long-term human data is still limited.
Irritation
low
Source
synthetic
A synthetic fragrance ester that adds a green, fruity scent but offers no skin benefit beyond fragrance.
Irritation
low
Source
synthetic
A synthetic fragrance ester that adds a fruity, green note to products; generally considered safe at low concentrations but offers no skincare benefits.
Irritation
low
Source
synthetic
A synthetic fragrance ester that adds a green, fruity scent to products; generally considered safe at low concentrations but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a pleasant floral-fruity note but offers no skincare benefits and may cause sensitivity in some people.
Irritation
low
Source
synthetic
Trans-2-Hexenyl Propionate is a synthetic fragrance ingredient that adds a green, fruity scent to products; it is generally considered safe at low concentrations but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic fragrance ester that adds a green, fruity scent; generally safe at low concentrations but offers no skincare benefit.
Irritation
low
Source
synthetic
A synthetic scent molecule that adds a tropical note to products, but offers no skincare benefit and may irritate sensitive skin.
Irritation
low
Source
synthetic
A gentle, strawberry-derived acid that may help exfoliate and brighten skin with low irritation potential, but research is still limited.
Irritation
low
Source
natural
Trans-2-Nonenal is a scent compound linked to an 'aging' body odor; it is rarely used in skincare for its own benefit and is more often a byproduct or a fragrance note.
Irritation
moderate
Source
synthetic
Trans-2-Octenal is a synthetic fragrance compound that adds a fresh, green scent but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic fragrance compound that adds a sweet, floral note to products; generally safe at low concentrations but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic cooling ingredient that creates a refreshing, minty sensation on skin without the strong scent of menthol, but may cause mild irritation in sensitive individuals.
Irritation
low
Source
synthetic
Trans-2-Undecenal is a synthetic fragrance ingredient that adds a fresh, citrusy note to products, but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic scent ingredient that adds a fresh, green note to products but offers no skincare benefit and may trigger sensitivity in some people.
Irritation
low
Source
synthetic
A synthetic fragrance compound that adds a green, leafy scent but offers no skincare benefits and may be a concern for those with fragrance sensitivities.
Irritation
low
Source
synthetic
Fragrance Ingredient
TRANS-3-METHYL-5-PHENYL-2-PENTENENITRILE
A synthetic fragrance ingredient that adds a fresh, citrusy scent; generally safe at low levels but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
Trans-5-Octenone is a synthetic fragrance ingredient with limited safety data; it is generally considered safe at low concentrations but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic fragrance ingredient that adds a pleasant scent but offers no skincare benefits; safe for most people at low concentrations.
Irritation
low
Source
synthetic
Trans-Isoocimenol is a synthetic fragrance ingredient that adds a fresh, green scent but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic scent ingredient that adds a fresh note but offers no skincare benefit; safe at low levels but may cause sensitivity in some people.
Irritation
low
Source
synthetic
A synthetic scent molecule that adds a tea-like note to products; generally safe at low levels but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a warm, woody note to products but offers no skincare benefit and may be unnecessary for sensitive skin.
Irritation
low
Source
synthetic
Trans-Rose Ketone-2 is a synthetic fragrance ingredient that adds a rose-like scent, but it may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic rose-scented fragrance ingredient that adds a pleasant floral note but offers no skincare benefits.
Irritation
low
Source
synthetic
Trans-Rose Ketone-5 is a synthetic fragrance ingredient that adds a rosy scent to products, but it may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic fragrance ingredient that adds a fresh scent but offers no skincare benefits and may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic fragrance compound that adds a fresh floral note but offers no skincare benefits and may be a concern for those sensitive to fragrance.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a warm, woody note to products, but offers no skincare benefit and may cause sensitivity in some people.
Irritation
low
Source
synthetic
A biotech peptide from transgenic rice that may support collagen and skin firmness, but human research is still limited.
Irritation
low
Source
biotech
A biotech rice peptide that may support collagen and skin firmness, but human research is still limited.
Irritation
low
Source
biotech
A lab-made peptide from silkworms that may help firm skin and reduce fine lines, but research is still early.
Irritation
low
Source
biotech
A biotech peptide from tobacco that may help reduce fine lines, but research is still limited compared to traditional peptides.
Irritation
low
Source
biotech
Transglutaminase is a biotech enzyme that may help reinforce the skin's structure, but its benefits in cosmetics are still being explored.
Irritation
low
Source
biotech
A botanical extract with traditional astringent uses, but limited modern research on its skincare benefits.
Irritation
low
Source
natural
A gentle, antioxidant-rich plant extract from tree peony callus that may help calm skin and fight free radical damage, though research is still emerging.
Irritation
low
Source
natural
A gentle botanical extract that helps protect skin from environmental stress and may calm irritation.
Irritation
low
Source
natural
A gentle, plant-derived antioxidant extract that may help calm skin and fight free radical damage, though human research is still limited.
Irritation
low
Source
natural
Tree Wormwood Herb Oil offers potential soothing and antimicrobial benefits, but its potency and lack of broad safety data mean it's best used in low concentrations and with caution.
Irritation
moderate
Source
natural
Trehalose is a gentle, natural humectant that pulls water into the skin and helps protect it from drying out, making it a great option for dry or sensitive skin.
Irritation
low
Source
natural
A gentle, moisture-binding ingredient that also helps reduce static and improve hair manageability.
Irritation
low
Source
semi-synthetic
A gentle, sugar-derived ester that hydrates and softens skin without clogging pores.
Irritation
low
Source
semi-synthetic
Trehalose undecylenate is a gentle, sugar-based ester that hydrates and softens skin with low irritation potential, though research on its long-term benefits is still emerging.
Irritation
low
Source
semi-synthetic
Tremella mushroom extract is a gentle, plant-based humectant that helps skin hold onto moisture, often compared to hyaluronic acid.
Irritation
low
Source
natural
A powerful prescription retinoid that effectively treats acne and reduces signs of aging, but requires careful use due to high irritation potential.
Irritation
high
Source
synthetic
A gentle, non-greasy emollient that improves skin feel and product spreadability without clogging pores.
Irritation
low
Source
synthetic
A mild synthetic emulsifier that helps blend oil and water in cleansers, generally well-tolerated but not a standout active ingredient.
Irritation
low
Source
synthetic
A mild synthetic emulsifier that helps blend oil and water in cleansers and lotions, generally well-tolerated by most skin types.
Irritation
low
Source
synthetic
An effective cleansing agent that helps remove dirt and oil, but may be slightly drying for sensitive skin.
Irritation
moderate
Source
synthetic
A mild synthetic surfactant that helps cleanse without stripping, but may cause irritation for very sensitive skin.
Irritation
moderate
Source
synthetic
A gentle, non-greasy emollient that helps skincare products spread smoothly and leaves skin feeling soft without clogging pores.
Irritation
low
Source
synthetic
Antioxidant
JUNIPERUS COMMUNIS FRUIT/ROSMARINUS OFFICINALIS/SALVIA OFFICINALIS EXTRACT
A gentle botanical blend that helps protect skin from environmental stress while offering a mild herbal scent.
Irritation
low
Source
natural
Soothing Agent
Artemisia Princeps Leaf/Equisetum Arvense/Houttuynia Cordata Extract
A gentle botanical blend that may help calm irritation and protect skin from environmental stress, though research on the specific combination is limited.
Irritation
low
Source
natural
Antioxidant
Nelumbo Nucifera Leaf Extract / Orostachys Japonica Extract / Saururus Chinensis Extract
A gentle botanical blend that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
A mild, citrate-based emulsifier that helps create stable, creamy textures without common irritation.
Irritation
low
Source
semi-synthetic
Triacetin is a gentle, low-risk solvent and skin conditioner often used to improve product texture and stability.
Irritation
low
Source
synthetic
A gentle, next-generation retinoid alternative that pairs vitamin A activity with skin-identical lipid support, but clinical evidence is still limited.
Irritation
low
Source
semi-synthetic