A synthetic fragrance compound that adds a pleasant woody scent but offers no skincare benefits and may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic fragrance compound that adds a pleasant woody scent but offers no skincare benefits and may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A widely used synthetic musk that provides a long-lasting clean scent, but has raised some environmental persistence concerns.
Irritation
low
Source
synthetic
A synthetic azulene derivative that adds a subtle fragrance and may offer mild soothing benefits, but research is limited and it's best for those without fragrance sensitivities.
Irritation
low
Source
synthetic
Fragrance Ingredient
HEXAHYDRO-TETRAMETHYL-METHANOAZULEN-5-ONE
A synthetic fragrance ingredient that adds a warm, woody scent but offers no skincare benefits and may be unnecessary for sensitive skin.
Irritation
low
Source
synthetic
Fragrance Ingredient
HEXAHYDRO-TETRAMETHYL-METHANOAZULEN-5-YL METHYL KETONE
A synthetic fragrance ingredient that adds a warm, woody scent but offers no skincare benefits and may cause irritation in sensitive individuals.
Irritation
low
Source
synthetic
Fragrance Ingredient
HEXAHYDRO-TETRAMETHYLMETHANONAPHTHALEN-8-ONE
A synthetic scent ingredient that adds a warm, floral note but may cause skin sensitivity in some people.
Irritation
moderate
Source
synthetic
A synthetic scent ingredient that adds a sweet, creamy note to products but offers no skincare benefit.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a pleasant floral-woody note but offers no skincare benefit and may cause sensitivity in some people.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a warm, woody aroma but offers no skincare benefits and may be unnecessary for sensitive skin.
Irritation
low
Source
synthetic
A lightweight, fast-evaporating silicone that improves product feel and spreadability without clogging pores.
Irritation
low
Source
synthetic
A synthetic wax that helps create a smooth, creamy texture in lip and skin products without clogging pores.
Irritation
low
Source
synthetic
Hexamethylene diisocyanate is a synthetic crosslinker used in nail products for durability, but it is a known irritant and sensitizer, making it unsuitable for leave-on skincare.
Irritation
high
Source
synthetic
A synthetic polymer that helps products stay put and resist water, but offers no active skincare benefit.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a warm, woody note but offers no skincare benefit and may trigger sensitivity in some people.
Irritation
low
Source
synthetic
A widely used synthetic musk that provides a pleasant scent but has raised some environmental and skin sensitivity concerns.
Irritation
low
Source
synthetic
Hexamidine is a gentle synthetic preservative that helps keep products fresh and may offer mild skin-soothing benefits.
Irritation
low
Source
synthetic
A gentle synthetic preservative that helps keep products fresh and may offer mild soothing benefits for the skin.
Irritation
low
Source
synthetic
A gentle synthetic preservative that helps keep skincare products fresh and safe from microbes, with a low irritation profile.
Irritation
low
Source
synthetic
Hexamidine Paraben is a synthetic preservative that helps keep products fresh, but it may cause irritation for sensitive skin types.
Irritation
moderate
Source
synthetic
Hexanal is a fragrance ingredient that adds a fresh scent but may cause skin irritation in sensitive individuals at higher concentrations.
Irritation
moderate
Source
synthetic
A synthetic fragrance ingredient that adds a fresh, green scent but offers no skincare benefits and may be a concern for those with fragrance sensitivities.
Irritation
low
Source
synthetic
Hexanediamine is a synthetic pH adjuster with limited direct skin benefit; it may cause irritation in sensitive individuals and is best left to professional or rinse-off products.
Irritation
moderate
Source
synthetic
Hexanediol is a gentle, multi-tasking ingredient that helps dissolve other ingredients, adds light hydration, and supports product preservation.
Irritation
low
Source
synthetic
Hexanediol Beeswax is a gentle, semi-synthetic emollient that helps lock in moisture and improve product texture without clogging pores.
Irritation
low
Source
semi-synthetic
A gentle exfoliating ester that helps smooth skin and improve texture with low irritation potential.
Irritation
low
Source
synthetic
A gentle emollient that helps skin feel soft and smooth without heavy greasiness.
Irritation
low
Source
synthetic
A gentle, non-greasy film former that helps products spread evenly and stay put without clogging pores.
Irritation
low
Source
synthetic
Film Former
Hexanediol/PEG-2 Cocomonium Chloride/TDI Copolymer
A synthetic polymer that helps cosmetics last longer and resist water, but offers no active skincare benefits.
Irritation
low
Source
synthetic
A gentle, semi-synthetic wax that helps products feel smooth and stay stable, but offers no active skincare benefits.
Irritation
low
Source
semi-synthetic
A peptide that mimics the action of botulinum toxin to soften expression lines, but with milder and temporary effects.
Irritation
low
Source
synthetic
Hexapeptide-1 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical version of neuromodulators.
Irritation
low
Source
synthetic
Hexapeptide-10 is a synthetic peptide that may help support collagen and elastin for firmer, smoother skin, but research is still emerging.
Irritation
low
Source
synthetic
Hexapeptide-11 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A novel hybrid of peptide and vitamin C that may support collagen and antioxidant defense, but research is still early.
Irritation
low
Source
semi-synthetic
Hexapeptide-32 is a lab-made peptide that may help soften expression lines and improve skin firmness, with a good safety profile for most skin types.
Irritation
low
Source
synthetic
Hexapeptide-33 is a gentle synthetic peptide that may help support skin firmness and resilience, but research is still early.
Irritation
low
Source
synthetic
Hexapeptide-34 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Hexapeptide-36 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to how a gentle muscle relaxant works.
Irritation
low
Source
synthetic
Hexapeptide-40 is a synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
Hexapeptide-44 is a synthetic peptide that may help support skin firmness and reduce the appearance of fine lines, but research is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that temporarily softens expression lines by calming muscle contractions, similar to a milder version of Argireline.
Irritation
low
Source
synthetic
Hexapeptide-47 is a synthetic peptide that may help calm skin and strengthen the moisture barrier, but research is still early.
Irritation
low
Source
synthetic
Hexapeptide-48 is a synthetic peptide that may help support skin firmness and reduce fine lines, but human research is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness with consistent use.
Irritation
low
Source
synthetic
Hexapeptide-49 is a lab-made peptide that may help improve skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Hexapeptide-50 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Hexapeptide-51 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Hexapeptide-52 is a synthetic peptide that may help soften expression lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
Hexapeptide-53 is a lab-made peptide that may help support skin firmness and smooth fine lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide designed to support collagen and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
Hexapeptide-56 is a lab-made peptide that may help support skin firmness and reduce fine lines, but research is still early and it's less studied than more common peptides.
Irritation
low
Source
synthetic
A peptide duo that may help smooth wrinkles and improve skin firmness, but results vary and more human studies are needed.
Irritation
low
Source
synthetic
Hexapeptide-57 is a synthetic peptide that may help soften expression lines and improve skin firmness, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Hexapeptide-58 is a lab-made peptide that may help soften expression lines and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Hexapeptide-61 is a synthetic peptide that may help support skin firmness and reduce the look of fine lines, though research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
Hexapeptide-62 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to other peptide ingredients.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth fine lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
Hexapeptide-63 is a synthetic peptide that may help support the look of firmer, smoother skin, but research is still emerging.
Irritation
low
Source
synthetic