Beauty ingredient research

Beauty ingredients explained in plain English

Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.

20769

Reviewed ingredients

524

Low-concern standouts

2884

Need usage caution

Showing 60 of 20,769
AllUV absorberUV filterabrasiveabsorbentacne treatmentactiveactive ingredientadhesivealkalizing agentamino acidanti-aginganti-androgenanti-cavityanti-cavity agentanti-inflammatoryanti-irritantanticariesanticavity agentantidandruffantifungalantimicrobialantioxidantantiperspirantantiplaqueastringentbarrier repairbarrier supportbarrier-repairbarrier-supportbinderbinding agentbiotechbiotechnologybond-builderbotanicalbotanical extractbotanical oilbotanical waterbrighteningbrightening agentbufferbuffering agentcell-communicating ingredientceramidechelating agentchemicalchemical intermediateclaycleansercleansingcleansing agentcolorantconditionerconditioningconditioning agentcooling agentcosmeticcosmetic additivecosmetic colorantcosmetic ingredientcosmetic pigmentcosmetic powdercosmetic-texturizercosmetic-waxcosmeticscrosslinking agentdelivery agentdelivery systemdenaturantdeodorantdeodorant agentdepigmenting agentdepilatorydepilatory agentdesensitizing agentdyedye intermediatedye precursordye-intermediateemollientemulsifierenzymeessential oilexfoliantexperimentaleyelashfermentfilm formerfilm-formerfilm-formingfilm-forming agentfirming agentfixativeflavoring agentformulationfragrancefragrance ingredientfunctional ingredientgashair carehair colorhair coloranthair conditionerhair dyehair removalhair-carehair-colorhaircarehumectantindustrialinsecticideintermediatelashlash carelash enhancerlash-and-browlip carelipidmakeupmarine extractmasking agentmicrobiomemicrobiome modulatormineralmoisturizernail carenail-careocclusiveoilopacifieropacifying agentoptical agentoral careotheroxidative dyeoxidative dye precursoroxidizing agentpH adjusterpain reliefpenetration enhancerpeptidepersonal careph adjusterpharmaceuticalpheromonepigmentplant oilplasticizerpolymerpolymer precursorprebioticprescription-drugpreservativepreservative boosterprobioticprocessing agentprocessing aidpropellantproteinpurifyingreducing agentretinoidscalp caresebum regulatorsebum-regulatorself-tannerself-tanningsensory additivesensory agentsensory modifiersiliconeskin barrierskin barrier supportskin conditionerskin conditioningskin conditioning agentskin lighteningskin protectantskin-conditioningskin-conditioning agentskin-identicalskin-identical ingredientskin-lighteningskin-lightening agentskincaresolventsoothingsoothing agentstabilizerstimulantsunscreensurfactantsyntheticsynthetic colorantsynthetic dyesynthetic resinsynthetic-coloranttexture enhancertexturizerthickenertoneruv-absorberuv-filtervasoactivevasodilatorviscosity controlviscosity controllingviscosity controlling agentvitaminwax

Fragrance Ingredient

Hexahydro-Methanoindenyl Propionate

HEXAHYDRO-METHANOINDENYL PROPIONATE

3.5

A synthetic fragrance compound that adds a pleasant woody scent but offers no skincare benefits and may cause sensitivity in some individuals.

Irritation

low

Source

synthetic

beautyskincarefragrance
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Fragrance Ingredient

Hexahydro-Tetramethyl-Benzopyran

HEXAHYDRO-TETRAMETHYL-BENZOPYRAN

4.0

A widely used synthetic musk that provides a long-lasting clean scent, but has raised some environmental persistence concerns.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Fragrance

Hexahydro-Tetramethyl-Epoxy-Methanoazulene

HEXAHYDRO-TETRAMETHYL-EPOXY-METHANOAZULENE

3.8

A synthetic azulene derivative that adds a subtle fragrance and may offer mild soothing benefits, but research is limited and it's best for those without fragrance sensitivities.

Irritation

low

Source

synthetic

beautyskincarefragrancesoothing
Read ingredient review

Fragrance Ingredient

Hexahydro-Tetramethyl-Methanoazulen-5-One

HEXAHYDRO-TETRAMETHYL-METHANOAZULEN-5-ONE

3.5

A synthetic fragrance ingredient that adds a warm, woody scent but offers no skincare benefits and may be unnecessary for sensitive skin.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Fragrance Ingredient

Hexahydrobenzofuranone

HEXAHYDRO-BENZOFURANONE

3.5

A synthetic scent ingredient that adds a sweet, creamy note to products but offers no skincare benefit.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Fragrance Ingredient

Hexahydromethoxymethanoindene

HEXAHYDROMETHOXY-METHANOINDENE

3.5

A synthetic scent ingredient that adds a pleasant floral-woody note but offers no skincare benefit and may cause sensitivity in some people.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Fragrance Ingredient

Hexahydropropenyloxy-Methanoindene

HEXAHYDROPROPENYLOXY-METHANOINDENE

3.5

A synthetic scent ingredient that adds a warm, woody aroma but offers no skincare benefits and may be unnecessary for sensitive skin.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Solvent

Hexamethyldisiloxane

Hexamethyldisiloxane

4.0

A lightweight, fast-evaporating silicone that improves product feel and spreadability without clogging pores.

Irritation

low

Source

synthetic

beautyskincaresiliconesolvent
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Crosslinking Agent

Hexamethylene Diisocyanate

HEXAMETHYLENE DIISOCYANATE

2.0

Hexamethylene diisocyanate is a synthetic crosslinker used in nail products for durability, but it is a known irritant and sensitizer, making it unsuitable for leave-on skincare.

Irritation

high

Source

synthetic

beautynail carecrosslinking agent
Read ingredient review

Fragrance

Hexamethylindan-5-ethanol

HEXAMETHYLINDAN-5-ETHANOL

3.8

A synthetic scent ingredient that adds a warm, woody note but offers no skincare benefit and may trigger sensitivity in some people.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Fragrance

Hexamethylindanopyran

HEXAMETHYLINDANOPYRAN

3.5

A widely used synthetic musk that provides a pleasant scent but has raised some environmental and skin sensitivity concerns.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

Preservative

Hexamidine

Hexamidine

4.0

Hexamidine is a gentle synthetic preservative that helps keep products fresh and may offer mild skin-soothing benefits.

Irritation

low

Source

synthetic

beautyskincarepreservative
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Preservative

Hexamidine Diisethionate

Hexamidine Diisethionate

4.0

A gentle synthetic preservative that helps keep products fresh and may offer mild soothing benefits for the skin.

Irritation

low

Source

synthetic

beautyskincarepreservative
Read ingredient review

Preservative

Hexamidine Diparabene

Hexamidine Diparabene

3.8

A gentle synthetic preservative that helps keep skincare products fresh and safe from microbes, with a low irritation profile.

Irritation

low

Source

synthetic

beautyskincarepreservative
Read ingredient review

Preservative

Hexamidine Paraben

Hexamidine Paraben

3.5

Hexamidine Paraben is a synthetic preservative that helps keep products fresh, but it may cause irritation for sensitive skin types.

Irritation

moderate

Source

synthetic

beautyskincarepreservative
Read ingredient review

Fragrance

Hexanal

Hexanal

3.5

Hexanal is a fragrance ingredient that adds a fresh scent but may cause skin irritation in sensitive individuals at higher concentrations.

Irritation

moderate

Source

synthetic

beautyskincarefragrance
Read ingredient review

Fragrance Ingredient

Hexanal Diethyl Acetal

Hexanal Diethyl Acetal

3.5

A synthetic fragrance ingredient that adds a fresh, green scent but offers no skincare benefits and may be a concern for those with fragrance sensitivities.

Irritation

low

Source

synthetic

beautyskincarefragrance
Read ingredient review

pH Adjuster

Hexanediamine

1,6-HEXANEDIAMINE

2.0

Hexanediamine is a synthetic pH adjuster with limited direct skin benefit; it may cause irritation in sensitive individuals and is best left to professional or rinse-off products.

Irritation

moderate

Source

synthetic

beautyskincarepH adjuster
Read ingredient review

Solvent

Hexanediol

Hexanediol

4.0

Hexanediol is a gentle, multi-tasking ingredient that helps dissolve other ingredients, adds light hydration, and supports product preservation.

Irritation

low

Source

synthetic

beautyskincaresolvent
Read ingredient review

Emollient

Hexanediol Beeswax

Hexanediol Beeswax

3.8

Hexanediol Beeswax is a gentle, semi-synthetic emollient that helps lock in moisture and improve product texture without clogging pores.

Irritation

low

Source

semi-synthetic

beautyskincareemollient
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Skin conditioning agent

Hexanediol Disalicylate

Hexanediol Disalicylate

3.5

A gentle exfoliating ester that helps smooth skin and improve texture with low irritation potential.

Irritation

low

Source

synthetic

beautyskincareexfoliant
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Emollient

Hexanetriol Beeswax

Hexanetriol Beeswax

3.8

A gentle, semi-synthetic wax that helps products feel smooth and stay stable, but offers no active skincare benefits.

Irritation

low

Source

semi-synthetic

beautyskincareemollient
Read ingredient review

Anti-aging agent

Hexapeptide-1

Hexapeptide-1

4.0

Hexapeptide-1 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical version of neuromodulators.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-10

Hexapeptide-10

4.0

Hexapeptide-10 is a synthetic peptide that may help support collagen and elastin for firmer, smoother skin, but research is still emerging.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-11

Hexapeptide-11

3.8

Hexapeptide-11 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Antioxidant

Hexapeptide-2 Ascorbyl Phosphate

Hexapeptide-2 Ascorbyl Phosphate

3.8

A novel hybrid of peptide and vitamin C that may support collagen and antioxidant defense, but research is still early.

Irritation

low

Source

semi-synthetic

beautyskincareantioxidantpeptide
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Anti-aging agent

Hexapeptide-32

Hexapeptide-32

4.0

Hexapeptide-32 is a lab-made peptide that may help soften expression lines and improve skin firmness, with a good safety profile for most skin types.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Skin conditioning agent

Hexapeptide-33

Hexapeptide-33

3.8

Hexapeptide-33 is a gentle synthetic peptide that may help support skin firmness and resilience, but research is still early.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-34

Hexapeptide-34

3.8

Hexapeptide-34 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-wrinkle agent

Hexapeptide-36

Hexapeptide-36

3.8

Hexapeptide-36 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to how a gentle muscle relaxant works.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-40

Hexapeptide-40

3.8

Hexapeptide-40 is a synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still limited compared to more established peptides.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-43

Hexapeptide-43

4.0

A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-44

Hexapeptide-44

4.0

Hexapeptide-44 is a synthetic peptide that may help support skin firmness and reduce the appearance of fine lines, but research is still limited.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-45

Hexapeptide-45

4.0

A synthetic peptide that temporarily softens expression lines by calming muscle contractions, similar to a milder version of Argireline.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Skin conditioning agent

Hexapeptide-47

Hexapeptide-47

3.8

Hexapeptide-47 is a synthetic peptide that may help calm skin and strengthen the moisture barrier, but research is still early.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-48

Hexapeptide-48

4.0

Hexapeptide-48 is a synthetic peptide that may help support skin firmness and reduce fine lines, but human research is still limited.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-48 HCl

Hexapeptide-48 HCl

4.0

A synthetic peptide that may help soften expression lines and improve skin firmness with consistent use.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-49

Hexapeptide-49

3.8

Hexapeptide-49 is a lab-made peptide that may help improve skin firmness and reduce fine lines, but research is still early and results vary.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-50

Hexapeptide-50

3.8

Hexapeptide-50 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-51

Hexapeptide-51

3.8

Hexapeptide-51 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-52

Hexapeptide-52

4.0

Hexapeptide-52 is a synthetic peptide that may help soften expression lines and improve skin firmness, but human data is still limited.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging

Hexapeptide-53

Hexapeptide-53

3.8

Hexapeptide-53 is a lab-made peptide that may help support skin firmness and smooth fine lines, but research is still early.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-54 Palmitate

Hexapeptide-54 Palmitate

4.0

A synthetic peptide designed to support collagen and reduce fine lines, with low irritation potential.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-56

Hexapeptide-56

3.8

Hexapeptide-56 is a lab-made peptide that may help support skin firmness and reduce fine lines, but research is still early and it's less studied than more common peptides.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging

Hexapeptide-56 Tripeptide-1

Hexapeptide-56, Tripeptide-1

4.0

A peptide duo that may help smooth wrinkles and improve skin firmness, but results vary and more human studies are needed.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-57

Hexapeptide-57

3.8

Hexapeptide-57 is a synthetic peptide that may help soften expression lines and improve skin firmness, but research is still emerging and results vary.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging

Hexapeptide-58

Hexapeptide-58

3.8

Hexapeptide-58 is a lab-made peptide that may help soften expression lines and improve skin firmness, but research is still early.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-61

Hexapeptide-61

3.8

Hexapeptide-61 is a synthetic peptide that may help support skin firmness and reduce the look of fine lines, though research is still emerging.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-61 Dimer

Hexapeptide-61 Dimer

4.0

A synthetic peptide that may help soften expression lines and improve skin firmness, but human data is still limited.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-62

Hexapeptide-62

4.0

Hexapeptide-62 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to other peptide ingredients.

Irritation

low

Source

synthetic

beautyskincareanti-aging
Read ingredient review

Anti-aging agent

Hexapeptide-62 Dimer

Hexapeptide-62 Dimer

4.0

A synthetic peptide that may help smooth fine lines and improve skin firmness, but human data is still limited.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review

Anti-aging agent

Hexapeptide-63

Hexapeptide-63

4.0

Hexapeptide-63 is a synthetic peptide that may help support the look of firmer, smoother skin, but research is still emerging.

Irritation

low

Source

synthetic

beautyskincarepeptide
Read ingredient review