Isopentane is a lightweight solvent that helps products feel less greasy, but it can be drying for very sensitive or dry skin.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
Isopentane is a lightweight solvent that helps products feel less greasy, but it can be drying for very sensitive or dry skin.
Irritation
low
Source
synthetic
Isopropyl acetate is a fast-evaporating solvent that helps products dry quickly, but it can be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
Effective for quick-drying and sanitizing, but can be drying and irritating for sensitive or dry skin types.
Irritation
moderate
Source
synthetic
A synthetic solvent that helps dissolve other ingredients and control product texture, but has limited direct skin benefit.
Irritation
low
Source
synthetic
A synthetic solvent and fragrance ingredient with limited research; may cause irritation in sensitive skin.
Irritation
moderate
Source
synthetic
Mesitylene is a synthetic solvent with limited cosmetic use; it may pose irritation risks and is not a common skincare ingredient.
Irritation
moderate
Source
synthetic
A synthetic solvent that helps products spread and dry, but may cause irritation for sensitive skin in high concentrations.
Irritation
moderate
Source
synthetic
A synthetic solvent that helps nail polish glide on smoothly and dry quickly, but may cause mild irritation for sensitive skin or prolonged contact.
Irritation
moderate
Source
synthetic
Methyl acetate is an effective solvent for removing nail polish, but it can be drying and irritating if used frequently or on sensitive skin.
Irritation
moderate
Source
synthetic
Methyl alcohol is a harsh solvent that can be drying and irritating; it is generally avoided in leave-on skincare and is more common in industrial or nail products.
Irritation
high
Source
synthetic
Methyl hexyl ether is a synthetic solvent that helps blend ingredients, but it has limited published safety data and may cause irritation in sensitive skin.
Irritation
moderate
Source
synthetic
MIBK is a strong industrial solvent with limited cosmetic use; it can be irritating and is best avoided in leave-on skincare.
Irritation
high
Source
synthetic
A strong solvent that can thin formulas but may irritate sensitive skin; best avoided in leave-on products.
Irritation
moderate
Source
synthetic
A functional solvent that helps products spread and feel lighter, but may cause irritation in sensitive individuals at high concentrations.
Irritation
moderate
Source
synthetic
A fast-drying, non-greasy fluid that helps products spread smoothly and feel lightweight on skin.
Irritation
low
Source
synthetic
A fast-evaporating synthetic fluid that helps products spread smoothly and feel weightless, but its environmental persistence raises concerns.
Irritation
low
Source
synthetic
Methyl pyrrolidone is a powerful solvent that can help ingredients absorb deeper, but its potential for irritation and safety concerns make it a less preferred choice in modern skincare.
Irritation
moderate
Source
synthetic
Methylal is an effective solvent that helps products spread and dry quickly, but it may cause irritation in sensitive skin and raises mild concerns about formaldehyde release.
Irritation
moderate
Source
synthetic
Mineral spirits are harsh petroleum solvents with high irritation potential, best avoided in everyday skincare.
Irritation
high
Source
synthetic
A synthetic diol that helps control product texture and stability, but is rarely a star ingredient on its own.
Irritation
low
Source
synthetic
Nitroethane is a synthetic solvent with limited cosmetic use; it may pose irritation risks and is not a common skincare ingredient.
Irritation
moderate
Source
synthetic
Nonane is a lightweight, volatile solvent that helps products spread easily and evaporate quickly, but it offers no active skincare benefits.
Irritation
low
Source
synthetic
Octane is a synthetic hydrocarbon that may act as a solvent in cosmetics, but it is rarely used in leave-on skincare and has limited safety data for topical use.
Irritation
moderate
Source
synthetic
Octene is a synthetic solvent that helps products spread smoothly and dissolve oils, but it offers no direct skin benefit.
Irritation
low
Source
synthetic
A solvent blend that helps dissolve other ingredients and may add a light scent, but can be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
Olive alcohol is a natural astringent that can help degrease oily skin but may be drying or irritating for sensitive types.
Irritation
moderate
Source
natural
A gentle synthetic solvent and humectant that helps other ingredients dissolve and spread, but offers no unique skin benefit on its own.
Irritation
low
Source
synthetic
A gentle synthetic solvent and humectant that helps other ingredients dissolve and spread, but offers no unique skin benefit on its own.
Irritation
low
Source
synthetic
PEG-400 is a widely used synthetic ingredient that helps dissolve other ingredients and improve texture, but its safety depends on purity and molecular weight.
Irritation
low
Source
synthetic
A gentle, water-soluble polymer that helps other ingredients absorb better and leaves skin feeling smooth without stickiness.
Irritation
low
Source
synthetic
A gentle, water-soluble polymer that helps other ingredients spread and absorb without leaving a greasy feel.
Irritation
low
Source
synthetic
A gentle, water-soluble polymer that helps other ingredients absorb better and leaves skin feeling smooth without greasiness.
Irritation
low
Source
synthetic
Pentane is a safe, fast-evaporating solvent used in sprays and mousses, but it offers no direct skin benefit.
Irritation
low
Source
synthetic
Pentanone is a strong solvent rarely used in skincare; it may cause irritation and is not a typical beneficial ingredient for skin health.
Irritation
moderate
Source
synthetic
Pentylene Glycol is a gentle, effective humectant that hydrates skin and helps preserve formulas without common irritation.
Irritation
low
Source
synthetic
Perfluorohexane is a lightweight synthetic liquid that helps products spread smoothly and evaporate quickly, but its environmental persistence raises concerns.
Irritation
low
Source
synthetic
A lightweight, volatile liquid that helps products spread smoothly and evaporates quickly, leaving a non-greasy feel—generally safe but best for those who tolerate silicones.
Irritation
low
Source
synthetic
A fast-evaporating synthetic liquid that helps products spread and dry quickly, but its environmental persistence raises concerns.
Irritation
low
Source
synthetic
PPG-16 is a safe, synthetic ingredient that helps other ingredients spread and absorb, but it offers no direct skin benefit.
Irritation
low
Source
synthetic
A safe, synthetic solvent that helps dissolve other ingredients and leaves a light, non-greasy feel on skin.
Irritation
low
Source
synthetic
A fast-evaporating solvent that helps products spread and dry quickly, but can be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
A gentle synthetic ingredient that helps products spread smoothly and feel lightweight on skin.
Irritation
low
Source
synthetic
A gentle synthetic solvent that helps other ingredients spread evenly without leaving a greasy feel.
Irritation
low
Source
synthetic
A synthetic solvent that helps products spread and dissolve oils, generally safe but not a star ingredient.
Irritation
low
Source
synthetic
Prenol is a synthetic alcohol used mainly as a solvent or fragrance component; it has little to no proven skincare benefit and may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Propyl Acetate helps products spread and dry quickly, but it can be drying or irritating for sensitive skin, especially around nails.
Irritation
moderate
Source
synthetic
Propyl alcohol is a solvent that helps ingredients mix and can kill bacteria, but it may strip moisture and irritate sensitive or dry skin.
Irritation
moderate
Source
synthetic
A mild synthetic solvent and fragrance ingredient that is generally safe at low concentrations but offers no direct skin benefit.
Irritation
low
Source
synthetic
Propylene carbonate is an effective solvent but can be irritating for sensitive skin; it's best reserved for rinse-off or low-concentration formulas.
Irritation
moderate
Source
synthetic
A functional solvent that helps products spread and mix, but may cause irritation for sensitive skin at higher concentrations.
Irritation
moderate
Source
synthetic
SD Alcohol 1 is a fast-evaporating solvent that can help products feel lightweight but may be drying and irritating for sensitive skin.
Irritation
high
Source
synthetic
SD Alcohol 23-A is a fast-evaporating solvent that can help products feel lightweight but may be drying or irritating for some skin types.
Irritation
moderate
Source
synthetic
Effective for quick-drying and oil control, but can be drying and irritating for sensitive or dry skin.
Irritation
moderate
Source
synthetic
SD Alcohol 23-H is a fast-evaporating solvent that can help products feel lightweight but may dry or irritate sensitive skin.
Irritation
moderate
Source
synthetic
SD Alcohol 27-B is a fast-evaporating solvent that can help products feel lightweight but may be drying or irritating for sensitive skin.
Irritation
high
Source
synthetic
SD Alcohol 31-A is a strong drying solvent that can help with oil control and product feel but may irritate sensitive or dry skin.
Irritation
high
Source
synthetic
SD Alcohol 36 is a fast-drying solvent that can help with oil control and product penetration, but it may strip the skin barrier and cause irritation with frequent use.
Irritation
high
Source
synthetic
SD Alcohol 37 helps products dry fast and feel clean, but can be drying and irritating for sensitive or dry skin.
Irritation
moderate
Source
synthetic
SD Alcohol 38-B is a fast-evaporating solvent that can help products feel lightweight but may be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic
SD Alcohol 38-C helps products dry quickly and feel light, but can be drying or irritating for sensitive skin.
Irritation
moderate
Source
synthetic