A synthetic fragrance ingredient that adds a pleasant floral note but offers no skincare benefit and may be a concern for those with fragrance sensitivities.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic fragrance ingredient that adds a pleasant floral note but offers no skincare benefit and may be a concern for those with fragrance sensitivities.
Irritation
low
Source
synthetic
Acetamide MEA is a synthetic humectant that helps hydrate skin and hair, but it is less common than alternatives like glycerin and may not suit those avoiding synthetic ingredients.
Irritation
low
Source
synthetic
Hair Conditioning Agent
Acetamidoethoxybutyl Trimonium Chloride
A gentle conditioning ingredient that helps reduce static and improve hair manageability without heavy buildup.
Irritation
low
Source
synthetic
A gentle, synthetic humectant that helps hydrate the skin without common irritation or clogging.
Irritation
low
Source
synthetic
A gentle synthetic conditioning ingredient that reduces frizz and static while improving the feel of hair and skin without heavy buildup.
Irritation
low
Source
synthetic
A gentle, synthetic ingredient that helps calm redness and sensitivity while supporting a more even skin tone.
Irritation
low
Source
synthetic
A gentle antistatic ingredient that smooths hair without heavy buildup, making it a good choice for fine or easily weighed-down hair.
Irritation
low
Source
synthetic
Acetaminosalol is a synthetic UV filter that helps protect skin from sun damage, but it may cause irritation for sensitive skin types.
Irritation
moderate
Source
synthetic
Acetic acid is a gentle exfoliant and pH adjuster, but can be irritating at high concentrations.
Irritation
moderate
Source
natural
A lightweight, non-greasy emollient that softens skin and improves product texture without clogging pores.
Irritation
low
Source
semi-synthetic
Film Former
TRIS(ACETIMINOACETOXYETHOXY METHACRYLATE) PPG-6 TRIMETHYLOLPROPANE
A synthetic film former that helps products stay put, but it's mostly used in specialty items like nail polish rather than everyday skincare.
Irritation
low
Source
synthetic
Acetoin is a gentle, natural humectant that helps hydrate skin and improve product texture without irritation.
Irritation
low
Source
natural
A synthetic fragrance ingredient with limited safety data; best for those who tolerate added scents.
Irritation
moderate
Source
synthetic
Acetone is a powerful but harsh solvent best reserved for quick, targeted removal of nail polish or stubborn adhesives, not for daily facial skincare.
Irritation
high
Source
synthetic
Acetophenone is a synthetic fragrance ingredient that adds a sweet, almond-like scent; it is generally considered safe at low concentrations but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
Fragrance Ingredient
ACETOPHENONE ETHYLENEGLYCOL CYCLIC ACETAL
A synthetic fragrance compound that adds a pleasant scent but offers no skincare benefits; safe at low concentrations but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic film-former that helps products stay put and resist water, but offers no active skincare benefit.
Irritation
low
Source
synthetic
A synthetic fragrance ingredient with limited safety data; best for those who tolerate synthetic scents well.
Irritation
moderate
Source
synthetic
UV Filter
ACETOXYTETRAMETHYLBUTYLPHENYL TETRAMETHYLBUTYLBENZOFURANONE
A synthetic UV filter that helps protect skin from sun damage, but its long-term safety data is still emerging.
Irritation
low
Source
synthetic
A gentle, water-loving amino acid derivative that helps plump skin and support its natural moisture barrier without irritation.
Irritation
low
Source
semi-synthetic
Acetyl Aspartic Acid is a gentle, water-soluble amino acid derivative that helps maintain skin hydration and supports a healthy skin barrier.
Irritation
low
Source
semi-synthetic
A synthetic hormone derivative that may help support skin firmness, but research is limited and it may not suit sensitive skin.
Irritation
moderate
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more independent research is needed.
Irritation
low
Source
synthetic
A mild, coconut-derived cleansing agent that effectively removes dirt and oil without stripping the skin’s natural moisture barrier.
Irritation
low
Source
semi-synthetic
Acetyl Carnitine is a gentle antioxidant that may help protect skin from environmental stress and support collagen health, but research is still emerging.
Irritation
low
Source
semi-synthetic
Acetyl Carnitine HCl is a gentle antioxidant that may help protect skin from environmental stress and support a more even tone, though it is not as well-studied as vitamin C or niacinamide.
Irritation
low
Source
semi-synthetic
A stable antioxidant peptide that helps protect skin from environmental damage and may support a more youthful appearance.
Irritation
low
Source
semi-synthetic
A gentle amino-acid derivative that may help support skin firmness and resilience, though research is still emerging.
Irritation
low
Source
semi-synthetic
A lab-made peptide that may help smooth fine lines and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
Acetyl Cysteine is a promising antioxidant and brightening ingredient, but research in topical skincare is still emerging compared to more established options like vitamin C.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help reduce the appearance of fine lines and improve skin firmness with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical alternative to injectables.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A gentle peptide that helps strengthen the skin barrier and soften the look of expression lines over time.
Irritation
low
Source
synthetic
A synthetic peptide-like ingredient that may help support skin firmness, but research is still early and benefits are not yet proven in large human studies.
Irritation
low
Source
synthetic
A gentle sugar-derived ingredient that supports skin renewal and surface smoothness, often used as a milder alternative to traditional exfoliants.
Irritation
low
Source
semi-synthetic
A mild, sugar-based ingredient that helps gently exfoliate and hydrate skin without the harshness of stronger acids.
Irritation
low
Source
semi-synthetic
Acetyl Glutamine is a gentle, water-loving amino acid derivative that helps keep skin plump and hydrated while supporting the skin's natural barrier.
Irritation
low
Source
semi-synthetic
A gentle, castor-oil-derived emollient that softens skin without feeling greasy.
Irritation
low
Source
semi-synthetic
A gentle peptide that helps maintain skin hydration and firmness, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce fine lines, with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to but milder than neuropeptides.
Irritation
low
Source
synthetic
A synthetic peptide that mimics natural signals to encourage firmer, smoother skin with low irritation risk.
Irritation
low
Source
synthetic
A synthetic musk-like fragrance ingredient that is generally considered safe at low concentrations but offers no skincare benefit beyond scent.
Irritation
low
Source
synthetic
A common synthetic musk fragrance that adds a warm, sweet scent but has raised some environmental and allergen concerns.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical version of neuromodulators.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and support firmer-looking skin with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce fine lines, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical version of neuromodulators.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to a milder, topical alternative to injectables.
Irritation
low
Source
synthetic
A synthetic peptide that temporarily softens expression lines by mimicking the action of a muscle-relaxing protein, offering a gentler alternative to injectables.
Irritation
low
Source
synthetic
A synthetic peptide that mimics the action of botulinum toxin to soften expression lines, but with a much milder and temporary effect.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A gentle peptide that may help soften expression lines over time, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A popular peptide that can soften dynamic wrinkles by relaxing facial muscles, but results are subtle and temporary.
Irritation
low
Source
synthetic
A synthetic peptide that helps soften expression lines by temporarily relaxing facial muscles, with good safety profile but modest, temporary results.
Irritation
low
Source
synthetic