A mild, amino-acid-based surfactant that cleanses without stripping the skin, making it a great choice for sensitive or dry skin types.
Irritation
low
Source
semi-synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A mild, amino-acid-based surfactant that cleanses without stripping the skin, making it a great choice for sensitive or dry skin types.
Irritation
low
Source
semi-synthetic
A gentle, amino-acid-based ingredient that helps control oil and support a balanced skin microbiome without stripping the skin.
Irritation
low
Source
semi-synthetic
A semi-synthetic ingredient that combines grape seed's antioxidant power with a fatty acid to potentially boost antimicrobial activity, though research is still emerging.
Irritation
low
Source
semi-synthetic
A gentle, semi-synthetic collagen derivative that forms a light film on skin to help retain moisture and improve texture.
Irritation
low
Source
semi-synthetic
A mild, plant-based emulsifier that helps create smooth, stable lotions and creams without common irritation.
Irritation
low
Source
semi-synthetic
A mild, oat-derived cleansing agent that cleans without stripping and may help calm sensitive skin.
Irritation
low
Source
semi-synthetic
A gentle, non-irritating brightener that targets dark spots by calming the signal that triggers excess pigment production.
Irritation
low
Source
synthetic
A mild, amino-acid-based surfactant that cleanses without stripping the skin, making it a great choice for sensitive or dry skin types.
Irritation
low
Source
semi-synthetic
Skin conditioner
UNDECENOYL SERINE/SILK AMINO ACID METHYL ESTERS
A gentle, semi-synthetic ingredient that conditions skin and hair while offering mild antimicrobial support, making it a good choice for sensitive formulas.
Irritation
low
Source
semi-synthetic
A mild, amino-acid-based cleanser that effectively removes dirt and oil while leaving skin feeling soft and balanced.
Irritation
low
Source
semi-synthetic
A gentle, dual-purpose ingredient that thickens formulas and offers mild antimicrobial support without irritation.
Irritation
low
Source
semi-synthetic
A gentle, castor-oil-derived alcohol that helps control odor-causing bacteria and fungi without drying out the skin.
Irritation
low
Source
natural
A gentle, synthetic emollient that softens skin and improves product spreadability without clogging pores.
Irritation
low
Source
synthetic
Uracil is a gentle, naturally derived skin conditioner with early research suggesting soothing benefits, but it is not yet a well-studied or widely used ingredient.
Irritation
low
Source
natural
A plant-based biotech ingredient with antioxidant potential, but research is still early and benefits are not yet proven in humans.
Irritation
low
Source
biotech
Urea is a gentle, effective humectant and exfoliant that hydrates and smooths skin, but higher concentrations can cause stinging on sensitive or broken skin.
Irritation
low
Source
natural
Urea peroxide offers mild exfoliation and whitening effects but can be irritating, especially at higher concentrations.
Irritation
moderate
Source
synthetic
A mild dual-action ingredient that gently exfoliates and hydrates, suitable for most skin types.
Irritation
low
Source
semi-synthetic
Urease is a natural enzyme that can gently exfoliate by breaking down urea, but its use in skincare is rare and may cause irritation if not carefully formulated.
Irritation
moderate
Source
natural
Uric acid is a gentle, natural antioxidant that helps protect skin from pollution and UV damage while supporting the skin's moisture barrier.
Irritation
low
Source
natural
Uridine is a gentle, naturally derived ingredient that may help support skin renewal and barrier repair, but research is still early.
Irritation
low
Source
biotech
Ursodiol is a bile acid with emerging research suggesting it may help calm inflammation and support the skin barrier, but it is not yet a mainstream skincare ingredient.
Irritation
low
Source
semi-synthetic
Ursolic acid is a plant-based antioxidant that may help calm skin and support a more even-looking complexion, but human studies are limited.
Irritation
low
Source
natural
A synthetic peptide that may help firm skin and reduce fine lines by signaling collagen production.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and smoothness, but research is still emerging.
Irritation
low
Source
synthetic
A promising synthetic peptide that may help improve skin firmness and reduce fine lines, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help improve skin firmness and smooth fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A gentle lichen-derived antioxidant that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
Usnea Filipendula Extract is a natural lichen extract with promising antimicrobial activity, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
Usnic acid is a lichen-derived compound with antimicrobial and antioxidant benefits, but it can be irritating at high concentrations and is not well-studied in long-term skincare use.
Irritation
moderate
Source
natural
A gentle tea-derived extract with antioxidant potential, but research is limited and benefits are not well-documented in human skin.
Irritation
low
Source
natural
Film Former
VA/BUTYL MALEATE/ISOBORNYL ACRYLATE COPOLYMER
A synthetic film-former that helps products stay put and resist water, but offers no active skincare benefit.
Irritation
low
Source
synthetic
A synthetic film-former that gives hair flexible hold and helps skincare ingredients stay put, but can feel stiff or cause buildup with heavy use.
Irritation
low
Source
synthetic
Film Former
VA/CROTONATES/METHACRYLOXYBENZOPHENONE-1 COPOLYMER
A synthetic polymer that helps sunscreen and makeup stay put longer, especially in water or sweat.
Irritation
low
Source
synthetic
A synthetic film-former that helps products stay put, but offers no active skincare benefit.
Irritation
low
Source
synthetic
A synthetic polymer that gives hair products their hold and flexibility without excessive stiffness or flaking.
Irritation
low
Source
synthetic
A synthetic film-former that helps products stay put, but may feel stiff or heavy on some skin types.
Irritation
low
Source
synthetic
Film Former
VA/ISOBUTYL MALEATE/VINYL NEODECANOATE COPOLYMER
A synthetic film-former that helps makeup and sunscreen stay put longer, but offers no active skincare benefit.
Irritation
low
Source
synthetic
A synthetic film-former that gives hair and makeup long-lasting, flexible hold without excessive stiffness or flaking.
Irritation
low
Source
synthetic
A synthetic film-former that helps products stay put, but its vinyl chloride component raises environmental and health questions.
Irritation
low
Source
synthetic
Valencene is a natural citrus-derived fragrance ingredient with mild antioxidant potential, but its main role in skincare is scent rather than active treatment.
Irritation
low
Source
natural
A gentle antioxidant-rich extract that helps protect skin from environmental stress and may support a brighter, more even complexion.
Irritation
low
Source
natural
Valencia orange peel oil adds a bright citrus scent and mild astringency, but can be irritating for sensitive skin, especially in sunlight.
Irritation
moderate
Source
natural
Valeraldehyde is a synthetic fragrance compound that adds a fruity scent but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic fragrance ingredient that adds a fresh scent but offers no skincare benefits and may cause sensitivity in some people.
Irritation
low
Source
synthetic
Valerian root extract is a gentle botanical with potential calming and antioxidant benefits, but research in skincare is limited.
Irritation
low
Source
natural
A gentle botanical extract with potential soothing and antioxidant benefits, but research is limited compared to more common skincare ingredients.
Irritation
low
Source
natural
Valeric acid is a naturally occurring fatty acid used mainly for its scent and to adjust product pH, but it can be irritating at higher concentrations.
Irritation
moderate
Source
natural
Valine is a gentle, water-loving amino acid that helps hydrate skin and support a healthy barrier, making it a safe choice for most skin types.
Irritation
low
Source
natural
A gentle, antioxidant-rich botanical extract that may help soothe and protect skin, though research is still emerging.
Irritation
low
Source
natural
A synthetic peptide that mimics a calming signal to help soothe reactive skin and support barrier repair.
Irritation
low
Source
synthetic
A gentle, antioxidant-rich botanical extract that adds a pleasant scent and may help calm skin, but its benefits are mild compared to more potent antioxidants.
Irritation
low
Source
natural
Vanilla fruit extract is a gentle antioxidant that helps protect skin from environmental stress while offering a subtle, natural scent.
Irritation
low
Source
natural
Vanilla Fruit Oil adds a warm, comforting scent and mild antioxidant benefits to skincare, but its fragrance components can irritate sensitive skin.
Irritation
moderate
Source
natural
A gentle, lightly fragrant water from vanilla pods that adds a subtle antioxidant boost and pleasant scent to skincare, but its benefits are mild compared to more concentrated extracts.
Irritation
low
Source
natural
A gentle, lab-grown antioxidant extract from vanilla leaves that may help calm and protect skin, but research is still early.
Irritation
low
Source
biotech
Vanilla Planifolia Tincture adds a warm, natural fragrance and mild antioxidant benefits to skincare, but its effects are subtle and not a primary active ingredient.
Irritation
low
Source
natural
A gentle, antioxidant-rich extract that may help calm skin and fight free radical damage, but research is still limited.
Irritation
low
Source
natural
Vanilla Seed Powder offers gentle physical exfoliation and antioxidant benefits, but its evidence is limited and it may not suit very sensitive skin.
Irritation
low
Source
natural
A gentle antioxidant that helps protect skin from environmental stress while supporting a calm, even-toned complexion.
Irritation
low
Source
natural