A well-studied synthetic peptide that helps firm skin and reduce fine lines by boosting collagen production.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A well-studied synthetic peptide that helps firm skin and reduce fine lines by boosting collagen production.
Irritation
low
Source
synthetic
Tripeptide-41 is a lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness by signaling collagen production.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with minimal irritation.
Irritation
low
Source
synthetic
A lab-made peptide that may help smooth wrinkles and improve skin firmness with very low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A lab-made peptide that may help support skin firmness and reduce fine lines, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but more human studies are needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
Tripeptide-54 is a lab-made peptide that may help support collagen production and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Tripeptide-56 is a synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Tripeptide-57 is a lab-made peptide that may help support skin firmness and smoothness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tripeptide-58 is a lab-made peptide that may help improve skin firmness and smooth fine lines, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
Tripeptide-60 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
Tripeptide-61 is a lab-made peptide that may help firm skin and soften wrinkles, but research is still emerging compared to more established peptides.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
Tripeptide-63 is a lab-made peptide that encourages your skin to produce more collagen and elastin, helping reduce fine lines and improve firmness.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and repair, but evidence is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Tripeptide-66 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Tripeptide-67 is a lab-made peptide that may help firm skin and soften fine lines, though research is still early compared to more established peptides.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
A peptide duo that may help soften expression lines and improve skin firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A peptide duo that may help improve skin firmness and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, with a good safety profile for most skin types.
Irritation
low
Source
synthetic
A silicone that gives a silky, smooth feel to products without clogging pores or causing irritation.
Irritation
low
Source
synthetic
A lightweight silicone that smooths skin and hair without feeling heavy or greasy.
Irritation
low
Source
synthetic
Antioxidant
Coix Lacryma-Jobi Ma-Yuen Seed/Pueraria Lobata Root/Ganoderma Lucidum Extract
A gentle botanical trio that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
natural
Antioxidant
Poncirus Trifoliata Fruit/Houttyunia Cordata/Hemerocallis Fulva Root Extract
A gentle botanical blend that may help calm skin and fight free radicals, but research is limited.
Irritation
low
Source
natural
Soothing Agent
ARTEMISIA DRACUNCULUS SEED/ANTHEMIS NOBILIS SEED/HYPERICUM ANDROSAEMUM SEED EXTRACT
A gentle botanical blend that may calm skin and fight free radicals, but research is limited and benefits are not guaranteed.
Irritation
low
Source
natural
A gentle, licorice-derived ingredient that helps calm redness and irritation without clogging pores.
Irritation
low
Source
natural
A plant-derived compound modified for stability that may help firm skin and reduce fine lines, but human studies are limited.
Irritation
low
Source
semi-synthetic
A gentle, synthetic emollient and solvent that helps products spread smoothly and prevents nail polish from becoming brittle.
Irritation
low
Source
synthetic
A plant-based extract with early research suggesting anti-inflammatory benefits, but limited human studies and potential for irritation.
Irritation
moderate
Source
natural
Triricinolein is a gentle, castor-oil-derived emollient that softens skin and helps lock in moisture without clogging pores.
Irritation
low
Source
natural
Tris Buffered Saline is a gentle pH buffer that helps keep skincare products stable and comfortable on sensitive skin.
Irritation
low
Source
synthetic
A synthetic stabilizer that helps keep formulas consistent, but is rarely the star ingredient.
Irritation
low
Source
synthetic
A stable synthetic antioxidant that helps prevent oils and other ingredients from going rancid, but it's not a star active for skin benefits.
Irritation
low
Source
synthetic
A highly effective, photostable UV filter that provides broad-spectrum protection with minimal irritation risk.
Irritation
low
Source
synthetic
A gentle synthetic dispersant that helps pigments and sunscreen actives spread evenly without irritation.
Irritation
low
Source
synthetic
A synthetic film-former that helps makeup last longer and resist water, but may feel stiff on skin.
Irritation
low
Source
synthetic
An effective preservative booster that helps keep products fresh, but may cause irritation for sensitive skin at higher concentrations.
Irritation
moderate
Source
synthetic
A mild synthetic surfactant that helps cleansers foam and rinse cleanly without stripping the skin.
Irritation
low
Source
synthetic
A synthetic silicone that helps products resist water and sweat, but may feel heavy on some skin types.
Irritation
low
Source
synthetic
A gentle synthetic preservative booster that helps keep your products fresh without the harshness of traditional preservatives.
Irritation
low
Source
synthetic
An effective preservative that works by releasing tiny amounts of formaldehyde, making it a controversial choice for sensitive skin.
Irritation
moderate
Source
synthetic
An effective synthetic antioxidant for preserving formulas, but its environmental and health profile raises caution.
Irritation
low
Source
synthetic
A gentle synthetic emollient that softens skin and improves product texture without clogging pores.
Irritation
low
Source
synthetic
A synthetic antioxidant that helps neutralize free radicals and stabilize formulas, but research on its skin benefits is still emerging.
Irritation
low
Source
synthetic
A silicone film former that helps products spread smoothly and resist water, but offers no active skincare benefits.
Irritation
low
Source
synthetic
A fast-evaporating silicone that gives a smooth, silky feel without heavy residue — great for lightweight formulas.
Irritation
low
Source
synthetic
A silicone-based film former that helps makeup and skincare last longer and feel smooth, with a low risk of irritation.
Irritation
low
Source
synthetic
A gentle peptide complex that may help calm redness and strengthen the skin barrier, but research is still early.
Irritation
low
Source
biotech
A gentle, stable vitamin C derivative that brightens skin and fights free radicals without the sting of pure ascorbic acid.
Irritation
low
Source
semi-synthetic
A gentle, stable vitamin C derivative that brightens skin and fights free radicals without the sting of pure ascorbic acid.
Irritation
low
Source
semi-synthetic
Trisodium Chlorin E6 is a light-activated compound used in professional treatments, not a daily skincare ingredient.
Irritation
moderate
Source
semi-synthetic