A synthetic scent ingredient that adds a warm, woody note but offers no skincare benefit and may be unnecessary for sensitive noses.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic scent ingredient that adds a warm, woody note but offers no skincare benefit and may be unnecessary for sensitive noses.
Irritation
low
Source
synthetic
Tetramethylammonium chloride is a synthetic salt used in tiny amounts as a processing aid; it has limited direct skin benefit and moderate irritation potential at higher concentrations.
Irritation
moderate
Source
synthetic
A synthetic fragrance ingredient that adds scent but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic antioxidant that helps shield skin from oxidative damage, but research is still limited compared to more established antioxidants.
Irritation
low
Source
synthetic
A gentle, stabilized antioxidant that may help defend skin against pollution and UV damage without irritation.
Irritation
low
Source
semi-synthetic
A synthetic scent ingredient that adds a warm, woody note but offers no skincare benefits and may cause sensitivity in some people.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a warm, woody note but offers no skin benefit and may cause sensitivity in some people.
Irritation
low
Source
synthetic
A synthetic fragrance ingredient that adds a pleasant floral note but offers no skincare benefits and may be unnecessary for sensitive skin.
Irritation
low
Source
synthetic
A synthetic emollient that helps soften and smooth skin with a low risk of irritation or clogged pores.
Irritation
low
Source
synthetic
Tetramethylhexanal is a synthetic fragrance ingredient that adds a fresh, citrusy note to products, but it may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic scent compound that adds a fresh note to products but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic film-former that helps products stay put, but it's not a star ingredient for skin health.
Irritation
low
Source
synthetic
Tetramethylpyrazine is a gentle antioxidant from fermented sources that may help calm skin and support microcirculation, though human skincare studies are still limited.
Irritation
low
Source
natural
Tetrandrine is a plant alkaloid with promising anti-inflammatory and antioxidant benefits, but research in topical skincare is still emerging.
Irritation
low
Source
natural
Tetrapeptide-1 is a gentle peptide that may help support collagen and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
Tetrapeptide-11 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still early and results can be subtle.
Irritation
low
Source
synthetic
Tetrapeptide-15 is a synthetic peptide that may help support collagen and reduce the appearance of fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
Tetrapeptide-2 is a gentle peptide that may help firm skin and reduce under-eye bags, but research is still emerging.
Irritation
low
Source
synthetic
Tetrapeptide-21 is a lab-made peptide that signals skin to produce more collagen, helping soften fine lines over time with a very low risk of irritation.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften fine lines, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften fine lines, with good tolerability for most skin types.
Irritation
low
Source
synthetic
Tetrapeptide-3 is a gentle peptide that may help firm skin and reduce under-eye puffiness, but research is still emerging.
Irritation
low
Source
synthetic
Tetrapeptide-36 is a synthetic peptide that may help support skin firmness and reduce fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-38 is a lab-made peptide that signals skin cells to boost collagen production, helping to smooth fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
Tetrapeptide-39 is a lab-made peptide that may help firm skin and reduce fine lines, but research is still early and it's less proven than more common peptides.
Irritation
low
Source
synthetic
A gentle peptide that may help reduce under-eye puffiness and support firmer-looking skin over time.
Irritation
low
Source
synthetic
Tetrapeptide-40 is a lab-made peptide that may help support skin structure and reduce signs of aging, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-41 is a lab-made peptide that may help support skin firmness and smoothness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-44 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide fused with a form of vitamin B3, aimed at supporting skin structure, but with limited independent research.
Irritation
low
Source
synthetic
Tetrapeptide-45 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-46 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-48 is a lab-made peptide that may help support skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-49 is a lab-made peptide that may help support skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-5 is a gentle, lab-made peptide that may help firm skin and reduce under-eye puffiness, but results are subtle and not instant.
Irritation
low
Source
synthetic
Tetrapeptide-51 is a lab-made peptide that may help firm and smooth skin by supporting collagen, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-52 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-53 is a lab-made peptide that may help support collagen and firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-54 is a synthetic peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-55 is a lab-made peptide that may help support skin firmness and reduce the look of fine lines, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-56 is a lab-made peptide that may help support skin firmness and reduce fine lines, but research is still early and it's less studied than more common peptides.
Irritation
low
Source
synthetic
A newer synthetic peptide that may help improve skin firmness and smoothness, but research is still limited.
Irritation
low
Source
synthetic
Tetrapeptide-57 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce wrinkles, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-58 is a lab-made peptide that may help improve skin firmness and smooth fine lines, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-59 is a lab-made peptide that may help support collagen production and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften fine lines, but human studies are still limited.
Irritation
low
Source
synthetic
Tetrapeptide-6 is a gentle, lab-made peptide that may help reduce under-eye puffiness and dark circles by supporting microcirculation and soothing the skin.
Irritation
low
Source
synthetic
Tetrapeptide-61 is a lab-made peptide that may help support skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-62 is a lab-made peptide that may help support collagen production and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Anti-aging agent
Tetrapeptide-62 Norleucyl Oligopeptide-149
A lab-made peptide duo that may help firm skin and soften lines, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-63 is a lab-made peptide that may help support skin structure and reduce signs of aging, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that may help improve skin firmness and smooth fine lines, but research is still early.
Irritation
low
Source
synthetic
Tetrapeptide-64 is a lab-made peptide that may help support collagen and firmness, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-65 is a lab-made peptide that may help support collagen and firm skin, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-67 is a promising synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still early and results vary.
Irritation
low
Source
synthetic
Tetrapeptide-67 Dimer is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A gentle, research-backed peptide that calms skin inflammation and supports collagen for a smoother, more resilient complexion.
Irritation
low
Source
synthetic