A lab-made peptide that may help firm skin and soften wrinkles, but human studies are still limited.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A lab-made peptide that may help firm skin and soften wrinkles, but human studies are still limited.
Irritation
low
Source
synthetic
RH-Polypeptide-60 is a lab-made peptide that may help firm skin and soften fine lines, but research is still early and results vary.
Irritation
low
Source
biotech
A lab-made peptide that may help support collagen and firm skin, but research is still early and results vary.
Irritation
low
Source
synthetic
RH-Polypeptide-62 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften fine lines, but human research is still limited.
Irritation
low
Source
biotech
A lab-made peptide that may help firm skin and soften wrinkles, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
RH-Polypeptide-65 is a synthetic peptide that may help support collagen production and improve skin firmness, but research is still emerging.
Irritation
low
Source
biotech
A lab-made peptide that may help firm skin and soften wrinkles, but human research is still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften wrinkles, but human studies are still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help reduce fine lines and improve skin firmness, but human research is still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin by encouraging collagen, but research is still limited compared to well-studied peptides.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but research is still early and results vary.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and firm skin, but human research is still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and firmness, but human research is still limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften wrinkles, but human studies are limited.
Irritation
low
Source
synthetic
RH-Polypeptide-88 is a lab-made peptide that may help firm skin and soften lines, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
RH-Polypeptide-94 is a synthetic peptide that may help firm skin and soften fine lines, but research is still early.
Irritation
low
Source
biotech
A promising synthetic peptide that may help firm and smooth skin, but research is still early and benefits vary by formulation.
Irritation
low
Source
semi-synthetic
RH-Polypeptide-96 is a lab-made peptide that may help support collagen and improve skin firmness, but human research is still limited.
Irritation
low
Source
synthetic
Rhamnose is a gentle plant-derived sugar that helps hydrate and lightly exfoliate skin, making it a good option for sensitive skin looking for mild renewal.
Irritation
low
Source
natural
Rhatany Root Extract is a gentle botanical astringent that can help tighten pores and calm irritation without stripping the skin.
Irritation
low
Source
natural
Rhein is a plant-derived antioxidant with emerging research for soothing and protecting skin, but more human studies are needed to confirm its benefits.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant potential, but research is limited and mostly traditional.
Irritation
low
Source
natural
A gentle botanical powder with antioxidant potential, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
A gentle botanical powder with traditional use for soothing skin, but modern evidence is limited.
Irritation
low
Source
natural
Rhizobian Gum is a gentle, natural thickener that improves product texture without clogging pores or causing irritation.
Irritation
low
Source
natural
A gentle, biotech-derived ferment that may help strengthen the skin barrier and support a healthy microbiome without irritation.
Irritation
low
Source
biotech
A gentle botanical extract with antioxidant potential, but research is limited and its benefits are not well-established.
Irritation
low
Source
natural
Humectant
RHIZOPUS/SACCHAROMYCES/COLLAGEN FERMENT FILTRATE
A fermented collagen ingredient that may help hydrate and condition skin, but research is still early and benefits are not yet proven in large human studies.
Irritation
low
Source
biotech
A gentle marine extract that helps hydrate and calm the skin, but research is still early.
Irritation
low
Source
natural
A gentle, hydrating microalgae extract that helps skin retain moisture and defends against environmental stress.
Irritation
low
Source
natural
Rhodinol is a natural fragrant alcohol that gives a rose-like scent, but it can be a skin sensitizer for some people.
Irritation
moderate
Source
natural
Rhodinyl acetate adds a pleasant rose-like scent to products, but may cause skin irritation in sensitive individuals at higher concentrations.
Irritation
moderate
Source
synthetic
A synthetic fragrance ester that adds a floral, rosy note to products; generally safe at low concentrations but may cause sensitivity in those with fragrance allergies.
Irritation
low
Source
synthetic
A synthetic rose-like fragrance ingredient that adds scent but offers no skincare benefit and may irritate sensitive skin.
Irritation
moderate
Source
synthetic
Rhodinyl isobutyrate is a synthetic fragrance ingredient that adds a floral, rose-like scent to products; it is generally safe at low concentrations but may cause irritation in sensitive individuals.
Irritation
low
Source
synthetic
A synthetic rose-like fragrance ingredient that adds a pleasant scent but offers no skincare benefits and may trigger sensitivities in some people.
Irritation
low
Source
synthetic
A synthetic floral scent ingredient that is generally safe at low levels but offers no skincare benefits.
Irritation
low
Source
synthetic
A synthetic floral scent ingredient that is generally safe at low levels but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A gentle, lab-grown antioxidant that helps protect skin from environmental stress without irritation.
Irritation
low
Source
biotech
A fermented botanical extract that may help calm skin and defend against environmental stress, though human studies are limited.
Irritation
low
Source
biotech
Rhodiola rosea callus extract is a gentle antioxidant that may help protect skin from environmental stress and support a more resilient complexion.
Irritation
low
Source
natural
Rhodiola rosea root extract is a gentle antioxidant-rich ingredient that may help protect skin from environmental stress and support a calm, even-looking complexion.
Irritation
low
Source
natural
A gentle, antioxidant-rich botanical that may help calm skin and defend against environmental stress.
Irritation
low
Source
natural
A gentle, biotech-derived ingredient that may help protect skin from environmental stress and support a healthy barrier.
Irritation
low
Source
biotech
Rhodochrosite is a natural mineral colorant with no proven skincare benefits beyond its pink hue.
Irritation
low
Source
natural
Rhododendrol is a plant-derived brightener that can help even skin tone, but it carries a moderate risk of irritation and has been linked to a rare skin-lightening disorder in some users.
Irritation
moderate
Source
natural
A gentle, antioxidant-rich botanical extract that may help calm and protect skin, but human studies are limited.
Irritation
low
Source
natural
A gentle, antioxidant-rich botanical extract that may help calm skin and protect against environmental stress, though human studies are limited.
Irritation
low
Source
natural
A gentle botanical powder that may offer soothing and antioxidant benefits, but research is limited and it primarily serves as a natural fragrance or texture enhancer.
Irritation
low
Source
natural
A gentle botanical powder with antioxidant and soothing potential, best for calm, non-reactive formulas.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant potential, but research on its specific skin benefits is still limited.
Irritation
low
Source
natural
A gentle, antioxidant-rich botanical extract that may help soothe and protect skin, but research is still early.
Irritation
low
Source
natural
A gentle, antioxidant-rich extract from alpine rhododendron that may help protect skin from environmental stress and soothe irritation.
Irritation
low
Source
natural
A gentle, antioxidant-rich flower extract that may help protect skin from environmental stress, but research is still early.
Irritation
low
Source
natural
Antioxidant
Bacillus/Rhododendron Weyrichii Flower Ferment Extract Filtrate
A gentle, fermented flower extract that may help calm skin and defend against environmental stress, though research is still early.
Irritation
low
Source
biotech
A gentle, lab-grown antioxidant from alpine rose that may help protect skin from environmental stress, though human studies are limited.
Irritation
low
Source
biotech
A gentle plant extract with antioxidant potential, though research is still early and benefits are not yet proven in human skin.
Irritation
low
Source
natural
A gentle, probiotic-derived antioxidant that may help calm skin and support a healthy skin barrier, though research is still emerging.
Irritation
low
Source
biotech