A mild, amino-acid-based surfactant that cleanses without stripping the skin’s natural moisture barrier.
Irritation
low
Source
semi-synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A mild, amino-acid-based surfactant that cleanses without stripping the skin’s natural moisture barrier.
Irritation
low
Source
semi-synthetic
Palmitoyl Glycine is a mild, amino-acid-based surfactant that cleanses without stripping the skin, making it a great choice for sensitive or dry skin types.
Irritation
low
Source
semi-synthetic
A gentle, peptide-inspired ingredient that helps improve skin firmness and smoothness without irritation.
Irritation
low
Source
semi-synthetic
A gentle, barrier-friendly ingredient that combines fatty acids with plant amino acids to help skin feel smooth and hydrated.
Irritation
low
Source
semi-synthetic
A stabilized antioxidant ingredient that helps protect skin from environmental stress and supports a more even-looking complexion.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived ingredient that may help support skin firmness and protect against environmental stress.
Irritation
low
Source
semi-synthetic
A stabilized, oil-friendly version of green tea extract that brings antioxidant and soothing power to formulas without the instability of plain green tea.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that mimics natural skin signals to help firm and smooth wrinkles with a low risk of irritation.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften the look of expression lines and support firmer-looking skin over time.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to appear firmer and smoother, with low irritation potential.
Irritation
low
Source
synthetic
A well-studied peptide that signals skin to produce more collagen, helping soften fine lines over time.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth wrinkles and improve skin firmness, with good tolerability for most skin types.
Irritation
low
Source
synthetic
A well-studied peptide that helps reduce fine lines and improve skin firmness with minimal irritation.
Irritation
low
Source
synthetic
A well-studied peptide that may help soften expression lines and improve skin firmness with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide designed to support collagen and improve skin firmness with low irritation risk.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth wrinkles and improve skin firmness with a low risk of irritation.
Irritation
low
Source
synthetic
A lipid-modified hyaluronic acid that may cling to skin longer than standard hyaluronic acid, offering targeted hydration.
Irritation
low
Source
semi-synthetic
A modified collagen peptide that may help support skin firmness and hydration with low irritation risk.
Irritation
low
Source
semi-synthetic
A gentle protein derivative that helps strengthen hair and lightly moisturize skin without heavy buildup.
Irritation
low
Source
semi-synthetic
A gentle conditioning ingredient that helps hair and skin feel smooth and soft, with low irritation risk.
Irritation
low
Source
semi-synthetic
A gentle film-forming ingredient that helps products spread smoothly and feel lightweight on skin.
Irritation
low
Source
semi-synthetic
A gentle, plant-based emulsifier that helps create stable, creamy textures without common irritation concerns.
Irritation
low
Source
semi-synthetic
A gentle, synthetic peptide-like ingredient that helps calm skin reactivity and support a more even-looking complexion.
Irritation
low
Source
synthetic
A gentle conditioning ingredient that helps strengthen hair and soften skin by delivering keratin amino acids with a fatty acid anchor.
Irritation
low
Source
semi-synthetic
Skin conditioning agent
N-PALMITOYL LAURYLACETYLMETHYL AMINOPROPANEDIOL
A synthetic peptide-like ingredient that helps strengthen the skin barrier and reduce the look of fine lines with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
A gentle, lipid-enriched mare milk derivative that may help moisturize and condition skin, but research is limited.
Irritation
low
Source
natural
A gentle, melatonin-inspired ingredient that may help calm skin and support overnight repair, but research is still early.
Irritation
low
Source
synthetic
A gentle, plant-based conditioning ingredient that helps soften and smooth skin without irritation.
Irritation
low
Source
semi-synthetic
A gentle, amino-acid-based ingredient that helps condition skin and stabilize formulas without common irritation.
Irritation
low
Source
synthetic
A synthetic peptide that mimics natural signals to encourage firmer, smoother-looking skin over time.
Irritation
low
Source
synthetic
A mild, oat-derived conditioning ingredient that leaves skin and hair feeling soft without heavy buildup.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help smooth fine lines and improve skin firmness, but more independent research is needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines by supporting collagen-related signaling, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and smooth fine lines, but individual results vary and more research is needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften wrinkles, but research is still emerging compared to more established peptides.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A gentle, antioxidant-rich ingredient that helps firm and protect skin, with good compatibility for most skin types.
Irritation
low
Source
semi-synthetic
A gentle, peptide-like ingredient that helps calm skin and reduce the look of redness without irritation.
Irritation
low
Source
semi-synthetic
A well-studied peptide that helps reduce fine lines and improve skin firmness by boosting collagen production.
Irritation
low
Source
synthetic
A well-studied peptide that can help reduce fine lines and improve skin firmness with consistent use.
Irritation
low
Source
synthetic
A well-studied peptide that may help reduce fine lines and support firmer-looking skin with consistent use.
Irritation
low
Source
synthetic
A gentle conditioning ingredient that helps detangle hair and reduce flyaways without heavy buildup.
Irritation
low
Source
synthetic
A gentle, antioxidant-rich ingredient that may help firm skin and reduce fine lines, but human studies are limited.
Irritation
low
Source
semi-synthetic
A gentle, semi-synthetic ingredient that combines the soothing power of tormentil root with enhanced skin compatibility.
Irritation
low
Source
semi-synthetic
Palmitoyl Proline is a synthetic peptide that may help support collagen production and improve skin firmness, but more human studies are needed to confirm its standalone effects.
Irritation
low
Source
synthetic
A gentle, plant-based peptide that may help support skin firmness and reduce the look of fine lines.
Irritation
low
Source
semi-synthetic
A gentle, semi-synthetic antioxidant that may help calm skin and fight free radicals, but research is still early.
Irritation
low
Source
semi-synthetic
Skin conditioning agent
Palmitoyl Serine/Silk Amino Acids Methyl Esters
A gentle conditioning ingredient that may help support skin barrier function and improve texture, but research is limited compared to more established peptides.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but results are gradual and vary by person.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more independent research is needed.
Irritation
low
Source
synthetic
Skin conditioning agent
Palmitoyl SH-Polypeptide-109 Cholesterol
A synthetic peptide-cholesterol hybrid that may help improve skin firmness and hydration, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften fine lines, but more independent human studies are needed.
Irritation
low
Source
synthetic