Nylon-66 is a safe, non-irritating synthetic powder that improves the feel and wear of makeup, but it is not biodegradable.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
Nylon-66 is a safe, non-irritating synthetic powder that improves the feel and wear of makeup, but it is not biodegradable.
Irritation
low
Source
synthetic
A gentle, antioxidant-rich flower extract that may help calm skin and fight free radical damage, but research is still emerging.
Irritation
low
Source
natural
A gentle, biotech-derived antioxidant from water lily cells that may help calm skin and fight free radical damage, though research is still early.
Irritation
low
Source
biotech
O-Allyloxyanisole is a synthetic fragrance ingredient with limited public safety data; it may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
O-Anisaldehyde is a synthetic fragrance compound that adds a sweet, floral scent to products but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
O-Cresyl Acetate is a synthetic fragrance ingredient that adds scent to products but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A gentle synthetic preservative that helps keep your skincare products fresh and safe without common irritation.
Irritation
low
Source
synthetic
o-Tolualdehyde is a synthetic fragrance ingredient that adds a cherry-like scent but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
O-Tolyl Biguanide is an effective preservative but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Oak bark extract is a natural astringent and antioxidant that can help tighten pores and protect skin from environmental damage, but it may be drying for some skin types.
Irritation
low
Source
natural
A gentle, antioxidant-rich plant extract that may help protect skin from environmental stress, though human studies are limited.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant potential, but research on its specific benefits for skin is still limited.
Irritation
low
Source
natural
Oak Gall Extract is a natural astringent that may help tighten pores and control oil, but it can be drying or irritating for sensitive skin types.
Irritation
moderate
Source
natural
Oak Root Extract is a gentle antioxidant-rich botanical that may help protect skin from environmental stress, but research on its specific benefits is still limited.
Irritation
low
Source
natural
A gentle, natural wood distillate that may help calm and clarify skin, but research is still emerging.
Irritation
low
Source
natural
Oakmoss extract is a classic natural fragrance ingredient with a rich, earthy scent, but it is also a common allergen that can cause skin reactions in sensitive individuals.
Irritation
moderate
Source
natural
Oat bran is a gentle, natural ingredient that soothes and moisturizes the skin, making it ideal for sensitive or irritated skin types.
Irritation
low
Source
natural
Oat bran extract is a gentle, natural ingredient that helps calm irritation and support the skin barrier, making it ideal for sensitive or reactive skin.
Irritation
low
Source
natural
A gentle, probiotic-based ingredient that helps calm irritation and strengthen the skin barrier, ideal for sensitive or reactive skin.
Irritation
low
Source
biotech
A gentle, plant-based juice that helps calm irritation and hydrate the skin, ideal for sensitive or reactive skin types.
Irritation
low
Source
natural
A gentle, natural exfoliant from oat hulls that polishes skin without harsh microbeads, ideal for sensitive skin types.
Irritation
low
Source
natural
Oat kernel extract is a gentle, antioxidant-rich ingredient that soothes and hydrates sensitive or irritated skin without clogging pores.
Irritation
low
Source
natural
Oat kernel flour is a gentle, soothing ingredient ideal for sensitive or irritated skin, offering mild exfoliation and moisture retention.
Irritation
low
Source
natural
A gentle, natural exfoliant and skin soother that's especially kind to sensitive and dry skin types.
Irritation
low
Source
natural
Oat kernel oil is a gentle, non-greasy emollient that softens and soothes dry or sensitive skin without clogging pores.
Irritation
low
Source
natural
Oat kernel protein is a gentle, hydrating ingredient that supports the skin barrier and soothes dryness without irritation.
Irritation
low
Source
natural
A gentle, antioxidant-rich extract that helps calm irritated skin and supports the skin barrier.
Irritation
low
Source
natural
A gentle, antioxidant-rich extract from oat leaves and stalks that helps calm and protect sensitive or irritated skin.
Irritation
low
Source
natural
A gentle, plant-based extract that helps calm irritated skin and provides antioxidant protection without clogging pores.
Irritation
low
Source
natural
Oat meal extract is a gentle, natural ingredient that calms irritation and supports the skin barrier, making it ideal for sensitive or reactive skin.
Irritation
low
Source
natural
Oat meristem cell extract is a gentle antioxidant-rich ingredient that may help calm skin and support a youthful appearance, though human studies are limited.
Irritation
low
Source
natural
Oat protein extract is a gentle, moisturizing ingredient that helps soothe and protect the skin barrier, making it ideal for sensitive or dry skin types.
Irritation
low
Source
natural
Oat seed water is a gentle, hydrating ingredient that helps calm sensitive or irritated skin without clogging pores.
Irritation
low
Source
natural
A gentle, antioxidant-rich oil from oat sprouts that helps soften and protect the skin without clogging pores.
Irritation
low
Source
natural
Oat straw extract is a gentle, antioxidant-rich ingredient that helps calm irritated skin and protect against environmental stress.
Irritation
low
Source
natural
Oatamide MEA is a mild, oat-based ingredient that helps cleansers foam gently while leaving skin and hair feeling soft and conditioned.
Irritation
low
Source
semi-synthetic
A gentle, plant-based surfactant that cleans without stripping, ideal for sensitive or dry skin.
Irritation
low
Source
natural
A mild, plant-derived conditioning ingredient that smooths hair and reduces static without heavy buildup.
Irritation
low
Source
semi-synthetic
A marine-inspired peptide that may help firm skin and reduce fine lines, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
Ocimene is a natural fragrant terpene that adds a fresh, herbal scent to products, but it may cause skin sensitivity in some people, especially at higher concentrations.
Irritation
moderate
Source
natural
Ocotea Quixos Leaf Oil adds a warm, spicy scent and offers antimicrobial benefits, but its moderate irritation risk means it's best for those without sensitive skin.
Irritation
moderate
Source
natural
A gentle plant extract that may help calm skin and fight free radicals, though research is still early.
Irritation
low
Source
natural
Skin conditioning agent
Octacarboxymethyl Dipeptide-12 Lysinamide
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation potential.
Irritation
low
Source
synthetic
A gentle, waxy emollient that helps soften and smooth skin while supporting the moisture barrier.
Irritation
low
Source
synthetic
A gentle synthetic emollient that helps skin feel soft and smooth without clogging pores, making it a safe choice for most skin types.
Irritation
low
Source
synthetic
A gentle conditioning ingredient that helps reduce static and improve manageability in hair products, with a low risk of irritation.
Irritation
low
Source
synthetic
Octadecane is a safe, lightweight emollient that softens skin and improves product texture without clogging pores.
Irritation
low
Source
synthetic
A synthetic emollient that makes products feel silky and spread easily, but offers no active skincare benefits.
Irritation
low
Source
synthetic
A safe, synthetic film-former that helps makeup and sunscreen stay put longer without feeling heavy.
Irritation
low
Source
synthetic
A gentle film-forming polymer that improves product feel and wear, with very low irritation potential.
Irritation
low
Source
semi-synthetic
A gentle, plant-derived alternative to hydroquinone that helps fade dark spots and even out skin tone without the irritation.
Irritation
low
Source
natural
A synthetic antioxidant that helps keep oils and butters fresh, extending product shelf life without directly benefiting skin.
Irritation
low
Source
synthetic
A synthetic film-former that helps products resist water and sweat, but its environmental persistence raises concerns.
Irritation
low
Source
synthetic
A synthetic scent ingredient that gives a warm, woody aroma but offers no skincare benefit and may cause sensitivity in some people.
Irritation
low
Source
synthetic
Fragrance Ingredient
OCTAHYDRO-5,5-DIMETHYLNAPHTHALENE-2-CARBALDEHYDE
A synthetic scent ingredient that adds a fresh, woody note but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Fragrance Ingredient
OCTAHYDRO-8,8-DIMETHYLNAPHTHALENE-2-CARBONITRILE
A synthetic scent ingredient that adds a fresh, woody note to products but offers no skincare benefit and may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
A synthetic azulene derivative used mainly for its pleasant scent and potential soothing effects, but research on its specific benefits is limited.
Irritation
low
Source
synthetic
Fragrance Ingredient
OCTAHYDRO-TETRAMETHYLCYCLOPROPANAPHTHALENONE
A synthetic fragrance ingredient that adds a warm, woody scent; generally safe at low levels but offers no skincare benefit.
Irritation
low
Source
synthetic
A synthetic scent ingredient that adds a warm, woody note but offers no skincare benefit and may be unnecessary for sensitive skin.
Irritation
low
Source
synthetic
Fragrance Ingredient
OCTAHYDRO-TETRAMETHYL-METHANO-CYCLOPENTACYCLOPROPABENZENE-4-METHANOL ACETATE
A synthetic fragrance ingredient that adds a woody, amber scent; generally considered safe at low concentrations but offers no skincare benefit.
Irritation
low
Source
synthetic