A lab-made peptide that may help smooth wrinkles and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A lab-made peptide that may help smooth wrinkles and improve skin firmness, but research is still early.
Irritation
low
Source
synthetic
A novel synthetic ingredient that pairs niacinamide with a garlic-derived compound for antioxidant and anti-aging effects, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide designed to mimic skin-repair signals, often used in anti-aging products for its potential to improve firmness and smooth wrinkles.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, with low irritation risk.
Irritation
low
Source
synthetic
A lab-made peptide-niacin hybrid that aims to firm skin and soften wrinkles, but human studies are still limited.
Irritation
low
Source
synthetic
A lab-made peptide-vitamin hybrid that aims to mimic natural skin signals to help smooth lines and improve firmness, with generally low irritation risk.
Irritation
low
Source
synthetic
A gentle peptide-niacinamide hybrid that helps firm skin and soften lines without irritation.
Irritation
low
Source
semi-synthetic
A promising synthetic peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A lab-made peptide that mimics niacinamide's benefits to help smooth wrinkles and improve skin texture with low irritation risk.
Irritation
low
Source
synthetic
A promising synthetic peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
Nicotinyl alcohol may help improve skin radiance by boosting blood flow, but it is less studied and potentially more irritating than niacinamide.
Irritation
moderate
Source
synthetic
Nictoflorin is a gentle plant antioxidant that may help calm skin and defend against environmental stress, but research is still early.
Irritation
low
Source
natural
A gentle, natural exfoliant that helps polish skin without harsh microbeads, but research on its specific benefits is still limited.
Irritation
low
Source
natural
A gentle, microbiome-friendly sugar that hydrates and helps balance skin bacteria without irritation.
Irritation
low
Source
biotech
A gentle plant extract with antioxidant potential, but research on its cosmetic benefits is still limited.
Irritation
low
Source
natural
A gentle, plant-based antioxidant extract that may help calm skin and fight free radicals, though research is still emerging.
Irritation
low
Source
natural
A gentle botanical extract with antioxidant potential, but research on its specific benefits for skin is still limited.
Irritation
low
Source
natural
A gentle, hydrating fruit extract with antioxidant potential, best for adding light moisture and protection to formulations.
Irritation
low
Source
natural
A gentle, natural exfoliant from cactus seeds that helps smooth skin without harsh microbeads.
Irritation
low
Source
natural
A gentle, fragrant botanical water that adds a pleasant scent and mild skin-conditioning benefits, but lacks strong scientific backing for specific skincare effects.
Irritation
low
Source
natural
A gentle plant extract that may help protect skin from environmental stress, though human studies are limited.
Irritation
low
Source
natural
A gentle plant extract with antioxidant potential, but research is still early and benefits are not yet proven in human skin.
Irritation
low
Source
natural
A gentle plant extract with antioxidant potential, but research is still early and benefits are not yet proven in human skin.
Irritation
low
Source
natural
A gentle, antioxidant-rich plant extract that may help protect skin from environmental stress, though research is still early.
Irritation
low
Source
natural
A gentle, plant-based antioxidant that may help protect skin from environmental stress, but research on its efficacy in cosmetics is still limited.
Irritation
low
Source
natural
Nisin is a gentle, naturally derived preservative that helps keep skincare products fresh while supporting a healthy skin microbiome.
Irritation
low
Source
natural
Nitroethane is a synthetic solvent with limited cosmetic use; it may pose irritation risks and is not a common skincare ingredient.
Irritation
moderate
Source
synthetic
Nitrogen is a safe, inert gas that helps dispense and preserve cosmetic products without affecting skin.
Irritation
low
Source
natural
A probiotic bacteria ferment that may support a balanced skin microbiome, but research is still early and product-specific results vary.
Irritation
low
Source
biotech
Nitrous oxide is a safe, non-irritating propellant that helps create light, airy textures in foaming products, but it offers no direct skin benefit.
Irritation
low
Source
synthetic
Nobiletin is a citrus-derived antioxidant that helps protect skin from environmental damage and may support a more even skin tone.
Irritation
low
Source
natural
A gentle, antioxidant-rich algae extract that may help soothe skin and fight environmental stress, but research is still early.
Irritation
low
Source
natural
Non-2-Enal is a synthetic fragrance compound that adds a fresh, green note to products but offers no skincare benefits beyond scent.
Irritation
low
Source
synthetic
Non-2-Enenitrile is a synthetic fragrance ingredient that adds a fresh, green scent but offers no skincare benefits and may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Nona-2,4-dienal is a synthetic fragrance ingredient that adds a fatty, aldehyde note but may cause skin irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Nonadecane is a gentle, lightweight emollient that helps soften skin and improve product texture without clogging pores.
Irritation
low
Source
natural
Nonadienol is a synthetic fragrance compound that adds a fresh violet scent to products; it is generally safe but may cause sensitivity in some individuals.
Irritation
low
Source
synthetic
Nonan-2-One is a synthetic fragrance ingredient that adds a fruity, floral note but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
Nonanal is a synthetic fragrance ingredient that adds a pleasant scent to products but may cause irritation in sensitive individuals.
Irritation
moderate
Source
synthetic
A synthetic fragrance compound that adds a pleasant scent but may cause skin sensitivity in some people, especially at higher concentrations.
Irritation
moderate
Source
synthetic
Nonane is a lightweight, volatile solvent that helps products spread easily and evaporate quickly, but it offers no active skincare benefits.
Irritation
low
Source
synthetic
A lightweight synthetic ester that helps skincare products feel silky and spread easily without greasiness.
Irritation
low
Source
synthetic
A synthetic ingredient that aims to soothe skin by mimicking natural calming signals, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that targets melanin production to help fade dark spots and even out skin tone, with low irritation potential.
Irritation
low
Source
synthetic
A targeted peptide that may help fade under-eye circles by improving blood flow and reducing pigment buildup.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to how neuropeptides work.
Irritation
low
Source
synthetic
A synthetic peptide blend that may help soften fine lines and improve skin firmness with consistent use.
Irritation
low
Source
synthetic
Anti-aging agent
NONAPEPTIDE-29 AMIDO CARBOXYMETHYL HYDROXYLIMINOMETHYLBENZAMIDO SH-DSRNA-1
A lab-made peptide complex that may help firm skin and soften lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide duo that may help soften expression lines and improve skin firmness with a low risk of irritation.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce the look of fine lines by signaling skin to produce more collagen, but human studies are still limited.
Irritation
low
Source
synthetic
Nonapeptide-31 is a synthetic peptide that may help soften expression lines by mimicking natural signaling processes in the skin.
Irritation
low
Source
synthetic
Nonapeptide-32 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to how neuropeptides work in skincare.
Irritation
low
Source
synthetic
Nonapeptide-33 is a synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to how neuropeptides work, but with a lower risk of irritation.
Irritation
low
Source
synthetic
Nonapeptide-34 is a synthetic peptide that may help soften expression lines, but research is still early and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines by signaling skin to produce more collagen, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften expression lines by temporarily relaxing facial muscles, similar to but milder than neurotoxins.
Irritation
low
Source
synthetic
A lab-made peptide that may help soften expression lines and improve skin firmness, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce the look of fine lines and improve skin firmness, though research is still emerging.
Irritation
low
Source
synthetic
Noneth-8 is a synthetic emulsifier that helps mix oil and water, but it may be mildly irritating for sensitive skin.
Irritation
moderate
Source
synthetic
A nutrient-dense ingredient that may support skin hydration and soothing, but human skincare research is still emerging.
Irritation
low
Source
natural