A lab-made peptide that may help smooth wrinkles and improve skin firmness, but human studies are still limited.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A lab-made peptide that may help smooth wrinkles and improve skin firmness, but human studies are still limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, with low irritation risk.
Irritation
low
Source
synthetic
SH-Oligopeptide-70 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still early and not as robust as for more established peptides.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A promising synthetic peptide that may help firm skin and reduce fine lines, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
A lab-made peptide that may help signal skin to produce more collagen, but research is still early and results vary.
Irritation
low
Source
synthetic
A synthetic peptide blend that may help support collagen and reduce fine lines, but human data is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen and elastin, helping reduce fine lines and improve firmness.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to look firmer and smoother, with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help support skin firmness and reduce fine lines, but more human studies are needed to confirm its effectiveness.
Irritation
low
Source
synthetic
A synthetic peptide amide that may help support skin firmness and reduce fine lines, though research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human studies are still limited.
Irritation
low
Source
synthetic
A lab-made peptide amide that may help support collagen for firmer-looking skin, but human studies are limited.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
A lab-made peptide that may help support firmer, smoother skin, though research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but research on this specific peptide is still limited.
Irritation
low
Source
synthetic
SH-Oligopeptide-88 is a lab-made peptide that may help support collagen and elastin for firmer, smoother skin, but research is still early.
Irritation
low
Source
synthetic
SH-Pentapeptide-40 is a lab-made peptide that may help support collagen and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A well-studied synthetic peptide that helps reduce wrinkles by boosting collagen and calming inflammation, with a strong safety profile.
Irritation
low
Source
synthetic
A synthetic peptide blend that may help support collagen production and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and reduce fine lines, but long-term human data is still limited.
Irritation
low
Source
synthetic
SH-Polypeptide-105 is a lab-made peptide that may help firm skin and reduce fine lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-11 is a lab-made peptide that may help support collagen production and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
SH-Polypeptide-110 is a lab-made peptide that may help support firmer, smoother skin, but research is still early and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but human studies are limited.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-18 is a synthetic peptide that mimics the action of botulinum toxin to soften expression lines, offering a non-invasive alternative for wrinkle reduction.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but results vary and long-term data is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to build more collagen, helping reduce fine lines over time.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines by signaling skin to produce more collagen, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
SH-Polypeptide-31 is a synthetic peptide that signals skin cells to boost collagen, helping reduce fine lines and improve firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-34 is a lab-made peptide that signals skin to look firmer and more youthful, with a good safety profile for most skin types.
Irritation
low
Source
synthetic
A lab-made peptide that may help support collagen and improve skin firmness, but more human studies are needed to confirm its effects.
Irritation
low
Source
synthetic
SH-Polypeptide-36 is a synthetic peptide that may help reduce fine lines by signaling skin cells to produce more collagen, but human studies are limited.
Irritation
low
Source
synthetic
SH-Polypeptide-37 is a lab-made peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A lab-made peptide that signals skin to produce more collagen, potentially reducing fine lines over time.
Irritation
low
Source
synthetic
SH-Polypeptide-40 is a lab-made peptide that may help support skin firmness and reduce the look of fine lines, but research is still early.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but research is still emerging and results vary by person.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, but human data is still limited.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-46 is a lab-made peptide that signals skin cells to boost collagen, helping smooth wrinkles over time with minimal irritation.
Irritation
low
Source
synthetic
SH-Polypeptide-49 is a lab-made peptide that may help support skin firmness and smooth fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth fine lines and support skin firmness, but human data is still limited compared to well-studied peptides.
Irritation
low
Source
synthetic
SH-Polypeptide-50 and SH-Polypeptide-56 are synthetic peptides designed to mimic natural signaling molecules that encourage firmer, smoother skin with minimal irritation risk.
Irritation
low
Source
synthetic
SH-Polypeptide-51 is a lab-made peptide that may help signal skin to produce more collagen, but research is still limited compared to more established peptides.
Irritation
low
Source
synthetic
SH-Polypeptide-53 is a lab-made peptide that may help reduce fine lines by encouraging the skin to produce more collagen, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-54 is a lab-made peptide that may help support collagen and elastin for firmer, smoother skin, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-55 is a lab-made peptide that may help reduce fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide duo that may help signal skin to look firmer and smoother, but research is still early and results vary.
Irritation
low
Source
synthetic
SH-Polypeptide-57 is a lab-made peptide that may help support collagen and make skin look firmer, but research is still early.
Irritation
low
Source
synthetic
SH-Polypeptide-58 is a synthetic peptide that signals skin cells to produce more collagen, helping reduce fine lines and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help reduce fine lines and improve skin firmness, but results vary and it works best in a consistent routine.
Irritation
low
Source
synthetic
A popular peptide that mimics the effects of Botox by temporarily relaxing facial muscles to soften expression lines.
Irritation
low
Source
synthetic
SH-Polypeptide-60 is a lab-made peptide that may help support collagen and reduce fine lines, but long-term human data is still limited.
Irritation
low
Source
synthetic