A synthetic peptide that may help reduce fine lines and improve skin firmness, but results vary and more human studies are needed.
Irritation
low
Source
synthetic
Beauty ingredient research
Browse the review database to understand what an ingredient is, what it does in a beauty formula, when it is useful, and when it deserves caution across skincare, haircare, bodycare, makeup, and more.
20769
Reviewed ingredients
524
Low-concern standouts
2884
Need usage caution
A synthetic peptide that may help reduce fine lines and improve skin firmness, but results vary and more human studies are needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help support collagen and improve skin firmness, but more human studies are needed.
Irritation
low
Source
synthetic
A lab-made peptide that mimics snail proteins to help skin look firmer and smoother, but it's not a proven alternative to retinol or collagen injections.
Irritation
low
Source
synthetic
A gentle synthetic peptide that may help soften fine lines by signaling skin to produce more collagen, but results are subtle and require consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more independent human studies are needed.
Irritation
low
Source
synthetic
A well-studied peptide that helps reduce fine lines by encouraging collagen production, but results are gradual and not dramatic.
Irritation
low
Source
synthetic
A well-studied peptide that helps reduce fine lines and support skin firmness with minimal irritation.
Irritation
low
Source
synthetic
A signaling peptide that encourages your skin to act younger by boosting collagen, but results are gradual and subtle.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping reduce fine lines and improve firmness with consistent use.
Irritation
low
Source
synthetic
A gentle peptide that may help improve skin firmness and reduce fine lines with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that encourages collagen production, helping reduce fine lines and improve skin firmness with minimal irritation.
Irritation
low
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but results are gradual and vary by person.
Irritation
low
Source
synthetic
A well-studied peptide that helps reduce fine lines and improve skin firmness with minimal irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that encourages firmer, smoother skin by supporting collagen-building signals.
Irritation
low
Source
synthetic
A synthetic peptide that mimics natural signals to help skin look firmer and smoother over time.
Irritation
low
Source
synthetic
A well-tolerated peptide that may help reduce fine lines and improve skin firmness by encouraging collagen production.
Irritation
low
Source
synthetic
Anti-aging agent
Palmitoyl SH-Tripeptide-5 Norisoleucyl SH-Nonapeptide-1
A synthetic peptide blend that may help soften fine lines and improve skin firmness with regular use, though results are gradual and not dramatic.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping to smooth wrinkles and improve firmness with consistent use.
Irritation
low
Source
synthetic
A synthetic peptide that signals skin to produce more collagen, helping to smooth wrinkles and improve firmness with low irritation risk.
Irritation
low
Source
synthetic
A promising synthetic peptide that may help firm skin and soften lines, though research is still emerging.
Irritation
low
Source
synthetic
A well-tolerated peptide that helps reduce fine lines and support skin firmness by encouraging collagen production.
Irritation
low
Source
synthetic
Palmitoyl Tryptamine is a synthetic peptide-like compound that may help support skin firmness and reduce fine lines, but research is still emerging and it is less common than more established peptides.
Irritation
low
Source
synthetic
Skin conditioning agent
Pisum Sativum (Pea) Phytoplacenta Conditioned Media
A gentle, plant-derived ferment that mimics the regenerative properties of animal placenta without the ethical or safety concerns.
Irritation
low
Source
biotech
Pentapeptide-33 is a lab-made peptide that signals skin to look firmer and smoother, but it works gradually and results vary.
Irritation
low
Source
synthetic
Pentapeptide-34 is a lab-made peptide that signals skin to produce more collagen, helping to smooth fine lines and improve firmness over time.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften lines, but research is still emerging compared to better-studied peptides.
Irritation
low
Source
synthetic
A lab-made peptide that may help support skin firmness and reduce the look of fine lines, with a good safety profile.
Irritation
low
Source
synthetic
Pentapeptide-45 is a lab-made peptide that may help firm skin and soften fine lines, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth fine lines and improve skin firmness with consistent use, though more independent research is needed.
Irritation
low
Source
synthetic
Pentapeptide-49 is a lab-made peptide that may help firm skin and soften fine lines by encouraging collagen, but research is still emerging.
Irritation
low
Source
synthetic
Pentapeptide-5 is a synthetic peptide that may help reduce fine lines and improve skin firmness, but results are gradual and vary by person.
Irritation
low
Source
synthetic
Pentapeptide-52 is a lab-made peptide that may help smooth wrinkles and improve skin firmness, but research is still emerging compared to well-studied peptides.
Irritation
low
Source
synthetic
A synthetic peptide that may help soften fine lines and improve skin firmness, with low irritation risk.
Irritation
low
Source
synthetic
A synthetic peptide that may help smooth fine lines and improve skin firmness, but research is still emerging.
Irritation
low
Source
synthetic
A lab-made peptide that may help firm skin and soften lines, but human research is still limited.
Irritation
low
Source
synthetic
Pentapeptide-57 is a lab-made peptide that may help smooth fine lines and support collagen, but research is still emerging and results vary.
Irritation
low
Source
synthetic
A lab-made peptide that aims to mimic natural signaling to help skin look firmer and smoother over time.
Irritation
low
Source
synthetic
A lab-made peptide that may help reduce fine lines by encouraging collagen, but results are gradual and vary by person.
Irritation
low
Source
synthetic
Pentapeptide-62 is a lab-made peptide that may help improve skin firmness and reduce fine lines, but more independent human studies are needed.
Irritation
low
Source
synthetic
Anti-aging agent
Pentasodium Tetracarboxymethyl Hexanoyl Dipeptide-12
A synthetic peptide that may help reduce fine lines and support skin firmness, but more human studies are needed.
Irritation
low
Source
synthetic
A peptide duo that may help improve skin firmness and reduce fine lines, but human studies are limited.
Irritation
low
Source
synthetic
Skin conditioning agent
Octapeptide-22, R-Thermus Thermophilus Putative Esterase, Hexapeptide-40
A cutting-edge peptide and ferment blend that may support skin firmness, but its unique ingredients lack broad independent research.
Irritation
low
Source
mixed
A novel biotech ingredient with promising anti-aging potential, but human research is still very limited.
Irritation
low
Source
biotech
A synthetic ingredient that may help improve skin firmness and reduce fine lines, but research is still limited compared to more established anti-aging ingredients.
Irritation
low
Source
synthetic
A synthetic peptide-like ingredient that may help improve skin firmness and elasticity, but research is still emerging.
Irritation
low
Source
synthetic
A gentle, plant-derived peptide that may help support skin structure, but research is still limited.
Irritation
low
Source
biotech
Pregnadienol is a synthetic steroid-like ingredient that may help smooth skin, but its safety and effectiveness are not well-established by independent research.
Irritation
moderate
Source
synthetic
A synthetic peptide that may help improve skin firmness and reduce fine lines, but more independent research is needed.
Irritation
low
Source
synthetic
A synthetic peptide that may help firm skin and soften wrinkles, but research is still emerging.
Irritation
low
Source
synthetic
A synthetic peptide blend that may help support collagen and reduce fine lines, but research is still emerging.
Irritation
low
Source
synthetic
A promising but under-researched peptide that may support collagen and skin repair, but lacks robust human studies.
Irritation
low
Source
semi-synthetic
A synthetic peptide that may help firm and smooth skin, but research is still early and benefits are not guaranteed.
Irritation
low
Source
synthetic
A novel peptide complex from fish sources that may support skin firmness and repair, but human research is very limited.
Irritation
low
Source
natural
A biotech-derived peptide that may help support skin firmness, but human research is still limited.
Irritation
low
Source
biotech
Retinal is a highly effective retinoid that works faster than retinol but may cause more irritation, making it best for experienced users seeking visible anti-aging results.
Irritation
moderate
Source
semi-synthetic
A gentler, more stable version of retinol that can help smooth fine lines and improve skin texture with less irritation.
Irritation
low
Source
semi-synthetic
A gentle peptide-retinoid hybrid that aims to support smoother, firmer skin without the typical irritation of pure retinol.
Irritation
low
Source
semi-synthetic
A gentler peptide-retinoid hybrid that aims to smooth fine lines and improve skin texture with less irritation than traditional retinol.
Irritation
low
Source
semi-synthetic
A gentler alternative to retinol that pairs retinoic acid with a peptide to support collagen and smooth fine lines with less irritation.
Irritation
low
Source
semi-synthetic
A gentle, water-soluble retinoid alternative that aims to smooth fine lines and improve skin texture with less irritation than traditional retinol.
Irritation
low
Source
semi-synthetic