Ingredient review

Streptomyces Avermitilis Ferment Filtrate

INCI: STREPTOMYCES AVERMITILIS/SOYBEAN EXTRACT FERMENT FILTRATE

A gentle, biotech-derived ferment that may help calm and condition the skin, though research is still emerging.

beautyskincaresoothing agent

In plain English

This ingredient is made by fermenting soybean extract with a specific soil bacterium (Streptomyces avermitilis). The fermentation process creates a liquid rich in peptides, amino acids, and other compounds that can help soothe and condition the skin. Think of it like a gentle, probiotic-inspired skin treatment that supports a healthy-looking complexion without harsh chemicals.

Review score

Safety, usefulness, and evidence

3.8Good
3.8/ 5

Potentially useful with some tradeoffs

The evidence base is still emerging, so marketing claims deserve extra caution.

Risk flags are low for most users, though the finished product can still irritate.

Source
biotech
Evidence
emerging
Irritation
low
Clogging risk
low
How reviews are scored

Quick decision guide

Useful, but context matters

Streptomyces Avermitilis Ferment Filtrate is generally a lower-concern ingredient when the full formula suits your skin.

Plain-English read

Treat this as a practical screening step before you compare products that contain this ingredient.

  1. Step 1Start with the score, then check the irritation and clogging risk before judging Streptomyces Avermitilis Ferment Filtrate.
  2. Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
  3. Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.

Score terms in plain English

Irritation risk

low

Less likely to sting, burn, or bother most users, though sensitive skin can still react.

Clogging risk

low

Less likely to feel heavy or contribute to clogged pores for most skin types.

Evidence level

emerging

The ingredient may be promising, but claims should be treated more cautiously.

What it is

A fermented filtrate produced by culturing the bacterium Streptomyces avermitilis on soybean extract, then filtering the liquid to collect the beneficial byproducts.

How it works

The fermentation process breaks down soybean proteins into smaller peptides and amino acids that can be more easily absorbed by the skin. These compounds may help calm irritation, support the skin's natural barrier, and provide antioxidant activity.

Pros

Gentle soothing potential

The fermentation process creates peptides and amino acids that may calm redness and irritation without the need for harsh active ingredients.

Supports skin barrier

The amino acids and peptides from fermented soybean can help reinforce the skin's natural moisture barrier, keeping hydration locked in.

Cons and cautions

Limited research

Most evidence comes from lab studies or broader ferment research; there are few dedicated human trials on this exact ingredient.

Soy allergy caution

Although highly processed, trace soy proteins could remain, so those with severe soy allergies should patch-test or avoid.

Best for

  • People with sensitive or reactive skin looking for gentle soothing ingredients
  • Anyone interested in biotech or fermented skincare for barrier support

Use caution if

  • Individuals with a known soy allergy should patch-test first, as trace residues may remain

Usage tips

Apply after cleansing and before heavier creams to allow the ferment filtrate to absorb fully.
Pair with a simple moisturizer to avoid overwhelming sensitive skin with too many active ingredients.

Safety summary

Considered safe for topical use with low irritation and comedogenic risk. The only notable concern is a potential (but rare) reaction in individuals with soy allergies. Always patch-test if you have sensitive skin.

Research notes

Research on this specific ingredient is limited, but broader studies on fermented soybean extracts suggest anti-inflammatory, antioxidant, and barrier-supporting benefits. More human trials are needed to confirm efficacy.

Common label clues

Typical concentration
Typically 1–5% in leave-on products
Regulatory status
Generally recognized as safe for cosmetic use in the US and EU when used as directed. No specific restrictions.
Common uses
Serums, Moisturizers, Soothing treatments
Environmental note
The fermentation process is relatively sustainable, using renewable soybean substrate and requiring less energy than synthetic chemical production.

Good to know

  • This ingredient is often found in K-beauty and J-beauty products that emphasize fermentation for skin health.
  • The bacterium used, Streptomyces avermitilis, is also known for producing the anti-parasitic compound ivermectin, but the skincare ingredient is purified and safe for topical use.

Common questions

What is Streptomyces Avermitilis Ferment Filtrate in beauty products?

This ingredient is made by fermenting soybean extract with a specific soil bacterium (Streptomyces avermitilis). The fermentation process creates a liquid rich in peptides, amino acids, and other compounds that can help soothe and condition the skin. Think of it like a gentle, probiotic-inspired skin treatment that supports a healthy-looking complexion without harsh chemicals.

What does Streptomyces Avermitilis Ferment Filtrate do in a beauty product?

The fermentation process breaks down soybean proteins into smaller peptides and amino acids that can be more easily absorbed by the skin. These compounds may help calm irritation, support the skin's natural barrier, and provide antioxidant activity.

Is Streptomyces Avermitilis Ferment Filtrate safe for most people?

Considered safe for topical use with low irritation and comedogenic risk. The only notable concern is a potential (but rare) reaction in individuals with soy allergies. Always patch-test if you have sensitive skin.

Who should be careful with Streptomyces Avermitilis Ferment Filtrate?

Individuals with a known soy allergy should patch-test first, as trace residues may remain

Research sources

Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.