Ingredient review
Lauroyl SH-Oligopeptide-76
INCI: Lauroyl SH-Oligopeptide-76
A synthetic peptide designed to support skin firmness and reduce fine lines, but research is still emerging.
In plain English
This ingredient is a lab-made peptide (a small protein fragment) that has been attached to a fatty acid called lauric acid. The fatty acid helps the peptide absorb into the skin more easily. Once inside, it signals skin cells to produce more collagen and elastin, which are the proteins that keep skin plump and firm. Think of it as a gentle messenger that tells your skin to act younger.
Review score
Safety, usefulness, and evidence
Potentially useful with some tradeoffs
The evidence base is still emerging, so marketing claims deserve extra caution.
Risk flags are low for most users, though the finished product can still irritate.
- Source
- synthetic
- Evidence
- emerging
- Irritation
- low
- Clogging risk
- low
Quick decision guide
Useful, but context matters
Lauroyl SH-Oligopeptide-76 is generally a lower-concern ingredient when the full formula suits your skin.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Lauroyl SH-Oligopeptide-76.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
lowLess likely to sting, burn, or bother most users, though sensitive skin can still react.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
emergingThe ingredient may be promising, but claims should be treated more cautiously.
What it is
Lauroyl SH-Oligopeptide-76 is a synthetic peptide ingredient. It consists of a short chain of amino acids (oligopeptide) chemically bonded to lauric acid, a fatty acid derived from coconut or palm oil. This modification improves the peptide's ability to penetrate the skin's outer layer.
How it works
The lauric acid tail helps the peptide slip through the skin barrier. Once in the deeper layers, the oligopeptide portion mimics natural signaling molecules that stimulate fibroblasts (skin cells) to produce more collagen and elastin. Over time, this can help reduce the appearance of fine lines and improve skin firmness.
Pros
Enhanced absorption
The lauric acid modification helps the peptide penetrate the skin more effectively than unmodified peptides, potentially improving results.
Gentle anti-aging support
It works by signaling your skin's own repair processes, making it a milder alternative to harsh exfoliants or retinoids.
Cons and cautions
Limited research
There are few published human studies on this specific peptide, so the evidence for its effectiveness is still emerging.
Variable results
Like many peptides, its performance depends heavily on the overall formulation and concentration, so not all products will deliver the same benefits.
Best for
- People looking for anti-aging benefits with minimal irritation
- Those who want a peptide ingredient that absorbs well into the skin
Use caution if
- Individuals with known allergies to coconut or palm-derived ingredients (though rare)
Usage tips
Safety summary
Lauroyl SH-Oligopeptide-76 is considered safe for topical use in cosmetics at typical concentrations. It has low irritation and comedogenic potential. As with any new ingredient, patch testing is recommended for sensitive individuals.
Research notes
Research on this specific peptide is limited. Most evidence comes from ingredient supplier studies and general peptide science. More independent clinical trials are needed to confirm its anti-aging benefits.
Common label clues
- Typical concentration
- Typically used at 0.1% to 2% in leave-on formulations
- Regulatory status
- Approved for use in cosmetics in the US, EU, and other major markets. No specific restrictions beyond general cosmetic safety requirements.
- Common uses
- Anti-aging serums, Eye creams, Facial moisturizers
- Environmental note
- The lauric acid is typically sourced from coconut or palm oil. Look for brands that use sustainably sourced palm oil if this is a concern.
Good to know
- Peptides are often listed near the end of ingredient lists because they are used at low concentrations.
- This ingredient is sometimes combined with other peptides or antioxidants for a synergistic effect.
Common questions
What is Lauroyl SH-Oligopeptide-76 in beauty products?
This ingredient is a lab-made peptide (a small protein fragment) that has been attached to a fatty acid called lauric acid. The fatty acid helps the peptide absorb into the skin more easily. Once inside, it signals skin cells to produce more collagen and elastin, which are the proteins that keep skin plump and firm. Think of it as a gentle messenger that tells your skin to act younger.
What does Lauroyl SH-Oligopeptide-76 do in a beauty product?
The lauric acid tail helps the peptide slip through the skin barrier. Once in the deeper layers, the oligopeptide portion mimics natural signaling molecules that stimulate fibroblasts (skin cells) to produce more collagen and elastin. Over time, this can help reduce the appearance of fine lines and improve skin firmness.
Is Lauroyl SH-Oligopeptide-76 safe for most people?
Lauroyl SH-Oligopeptide-76 is considered safe for topical use in cosmetics at typical concentrations. It has low irritation and comedogenic potential. As with any new ingredient, patch testing is recommended for sensitive individuals.
Who should be careful with Lauroyl SH-Oligopeptide-76?
Individuals with known allergies to coconut or palm-derived ingredients (though rare)
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.