Ingredient review
Hyaluronic Acid/Polyglutamic Acid Crosspolymer
INCI: Hyaluronic Acid/Polyglutamic Acid Crosspolymer
A next-generation humectant that binds more water and stays on skin longer than standard hyaluronic acid.
In plain English
This ingredient is a special version of hyaluronic acid (a moisture magnet) linked with polyglutamic acid (another moisture-binding molecule). The crosslinking creates a larger, stable network that sits on the skin's surface, holding onto water more effectively and for a longer time than regular hyaluronic acid. It helps plump and hydrate without feeling sticky or heavy.
Review score
Safety, usefulness, and evidence
Strong fit for many routines
The evidence base is useful, but some claims depend heavily on the formula.
Risk flags are low for most users, though the finished product can still irritate.
- Source
- semi synthetic
- Evidence
- moderate
- Irritation
- low
- Clogging risk
- low
Quick decision guide
Easy yes for most routines
Hyaluronic Acid/Polyglutamic Acid Crosspolymer is generally a lower-concern ingredient when the full formula suits your skin.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Hyaluronic Acid/Polyglutamic Acid Crosspolymer.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
lowLess likely to sting, burn, or bother most users, though sensitive skin can still react.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
moderateThere is useful support, but formula details and claim strength still matter.
What it is
A crosslinked polymer made by chemically bonding hyaluronic acid and polyglutamic acid. This creates a larger molecular structure that forms a breathable, hydrating film on the skin.
How it works
When applied, the crosspolymer forms a thin, flexible film on the skin that traps moisture from the environment and from underlying layers. Its larger size prevents deep penetration, so it stays on the surface where it continuously hydrates and reduces water loss (transepidermal water loss, or TEWL — the water that evaporates from your skin).
Pros
Superior water binding
The crosspolymer structure holds more water than standard hyaluronic acid, giving you longer-lasting hydration that doesn't evaporate quickly.
Gentle and non-irritating
With a low irritation risk, it's suitable for sensitive skin types and won't clog pores, making it a safe choice for most routines.
Cons and cautions
Can feel slightly tacky
In higher concentrations or if applied too thickly, it may leave a light sticky or film-like feel on the skin, which some people dislike.
Needs a partner in dry air
In very low-humidity environments, it can draw moisture from deeper skin layers if not sealed with an occlusive moisturizer, potentially causing dryness.
Best for
- Anyone with dry or dehydrated skin looking for deeper hydration
- People who find regular hyaluronic acid not hydrating enough or too short-lived
Use caution if
- Those who prefer extremely lightweight, watery textures and dislike any film feel
Usage tips
Safety summary
Considered safe for topical use with very low irritation and comedogenic potential. No significant safety concerns reported in cosmetic concentrations.
Research notes
Studies show crosslinked hyaluronic acid derivatives provide superior and longer-lasting hydration compared to linear hyaluronic acid. Polyglutamic acid is also well-documented for its moisture-binding ability. However, direct clinical data on this specific crosspolymer is still emerging.
Common label clues
- Typical concentration
- 0.1% to 2%
- Regulatory status
- Approved for cosmetic use globally, including by the FDA (as a cosmetic ingredient) and under EU cosmetics regulation. No known restrictions.
- Common uses
- Serums, Moisturizers, Sheet masks, Eye creams
- Environmental note
- Produced through controlled chemical synthesis; no known significant environmental concerns at typical usage levels.
Good to know
- This ingredient is often listed near the top of ingredient lists because it's used at low concentrations but is very effective.
- It pairs well with other humectants like glycerin and niacinamide for a multi-layer hydration boost.
Common questions
What is Hyaluronic Acid/Polyglutamic Acid Crosspolymer in beauty products?
This ingredient is a special version of hyaluronic acid (a moisture magnet) linked with polyglutamic acid (another moisture-binding molecule). The crosslinking creates a larger, stable network that sits on the skin's surface, holding onto water more effectively and for a longer time than regular hyaluronic acid. It helps plump and hydrate without feeling sticky or heavy.
What does Hyaluronic Acid/Polyglutamic Acid Crosspolymer do in a beauty product?
When applied, the crosspolymer forms a thin, flexible film on the skin that traps moisture from the environment and from underlying layers. Its larger size prevents deep penetration, so it stays on the surface where it continuously hydrates and reduces water loss (transepidermal water loss, or TEWL — the water that evaporates from your skin).
Is Hyaluronic Acid/Polyglutamic Acid Crosspolymer safe for most people?
Considered safe for topical use with very low irritation and comedogenic potential. No significant safety concerns reported in cosmetic concentrations.
Who should be careful with Hyaluronic Acid/Polyglutamic Acid Crosspolymer?
Those who prefer extremely lightweight, watery textures and dislike any film feel
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.