Ingredient review

Dihydromyricetin

INCI: Dihydromyricetin

A plant-derived antioxidant that helps calm skin and defend against environmental stress, with emerging research for anti-aging benefits.

beautyskincareantioxidant

In plain English

Dihydromyricetin is a natural compound found in plants like the Japanese raisin tree. In skincare, it works as an antioxidant, meaning it helps neutralize unstable molecules called free radicals that can damage skin cells and speed up visible aging. It also has soothing properties, which can help reduce redness and irritation. Think of it as a gentle shield for your skin against daily pollution and sun exposure.

Review score

Safety, usefulness, and evidence

4.0Good
4.0/ 5

Potentially useful with some tradeoffs

The evidence base is useful, but some claims depend heavily on the formula.

Risk flags are low for most users, though the finished product can still irritate.

Source
natural
Evidence
moderate
Irritation
low
Clogging risk
low
How reviews are scored

Quick decision guide

Useful, but context matters

Dihydromyricetin is generally a lower-concern ingredient when the full formula suits your skin.

Plain-English read

Treat this as a practical screening step before you compare products that contain this ingredient.

  1. Step 1Start with the score, then check the irritation and clogging risk before judging Dihydromyricetin.
  2. Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
  3. Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.

Score terms in plain English

Irritation risk

low

Less likely to sting, burn, or bother most users, though sensitive skin can still react.

Clogging risk

low

Less likely to feel heavy or contribute to clogged pores for most skin types.

Evidence level

moderate

There is useful support, but formula details and claim strength still matter.

What it is

Dihydromyricetin (DHM) is a flavonoid, a type of plant pigment with antioxidant activity. It is extracted primarily from the leaves and stems of the Japanese raisin tree (Hovenia dulcis) and is also found in some teas and herbs. In cosmetics, it is used as a functional ingredient to protect and calm the skin.

How it works

Dihydromyricetin works by donating electrons to neutralize free radicals, preventing them from causing oxidative stress that can lead to collagen breakdown and inflammation. It also inhibits certain enzymes involved in the inflammatory response, helping to reduce skin redness and sensitivity. Additionally, some research suggests it may support the skin's natural repair processes by promoting healthy cell turnover.

Pros

Gentle antioxidant protection

Dihydromyricetin helps neutralize free radicals from pollution and UV exposure without causing irritation, making it suitable for sensitive skin types.

Soothing properties

It can help calm redness and inflammation, which is beneficial for those with rosacea or general skin sensitivity.

Cons and cautions

Less research than classic antioxidants

Compared to vitamin C or vitamin E, dihydromyricetin has fewer human studies proving its long-term anti-aging effects in skincare.

Stability concerns

Like many flavonoids, it can degrade when exposed to light and air, so product packaging (opaque, airtight) is important for effectiveness.

Best for

  • Anyone looking for a gentle antioxidant to protect against pollution and UV stress
  • People with sensitive or reactive skin who want soothing ingredients

Use caution if

  • Those seeking a proven, high-potency antioxidant with extensive clinical backing (consider vitamin C instead)

Usage tips

Use in the morning under sunscreen to boost protection against environmental damage.
Pair with other antioxidants like vitamin E for a synergistic effect.
Store products containing dihydromyricetin in a cool, dark place to preserve potency.

Safety summary

Dihydromyricetin is considered safe for topical use in cosmetics. It has low irritation and comedogenic potential, making it suitable for most skin types. As with any new ingredient, a patch test is recommended for those with very sensitive skin.

Research notes

Research on dihydromyricetin in skincare is promising but still emerging. In vitro and animal studies show strong antioxidant and anti-inflammatory activity. Human studies are limited but suggest benefits for skin hydration and barrier function. More clinical trials are needed to confirm its anti-aging efficacy compared to established antioxidants.

Common label clues

Typical concentration
0.1% to 2%
Regulatory status
Generally recognized as safe for cosmetic use in the EU and US, with no specific restrictions at typical concentrations.
Common uses
Serums, Moisturizers, Eye creams
Environmental note
Sourced from the Japanese raisin tree, which is cultivated in parts of Asia. Sustainable harvesting practices are recommended to protect wild populations.

Good to know

  • Dihydromyricetin is also studied for its potential to support liver health when taken orally, but this is separate from its topical use.
  • It is sometimes listed as 'ampelopsin' on ingredient labels.

Common questions

What is Dihydromyricetin in beauty products?

Dihydromyricetin is a natural compound found in plants like the Japanese raisin tree. In skincare, it works as an antioxidant, meaning it helps neutralize unstable molecules called free radicals that can damage skin cells and speed up visible aging. It also has soothing properties, which can help reduce redness and irritation. Think of it as a gentle shield for your skin against daily pollution and sun exposure.

What does Dihydromyricetin do in a beauty product?

Dihydromyricetin works by donating electrons to neutralize free radicals, preventing them from causing oxidative stress that can lead to collagen breakdown and inflammation. It also inhibits certain enzymes involved in the inflammatory response, helping to reduce skin redness and sensitivity. Additionally, some research suggests it may support the skin's natural repair processes by promoting healthy cell turnover.

Is Dihydromyricetin safe for most people?

Dihydromyricetin is considered safe for topical use in cosmetics. It has low irritation and comedogenic potential, making it suitable for most skin types. As with any new ingredient, a patch test is recommended for those with very sensitive skin.

Who should be careful with Dihydromyricetin?

Those seeking a proven, high-potency antioxidant with extensive clinical backing (consider vitamin C instead)

Research sources

PubMed: Antioxidant and anti-inflammatory effects of dihydromyricetinOpenCosIng (EU Cosmetic Ingredient Database)Open

Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.