Ingredient review
Dechloro Cyclopropylcloprostenolamide
INCI: Dechloro Cyclopropylcloprostenolamide
A synthetic ingredient that may help lashes appear longer and fuller, but it can cause irritation and has limited long-term safety data for cosmetic use.
In plain English
This is a lab-made ingredient similar to a natural substance called prostaglandin. In eyelash serums, it's thought to encourage lashes to grow longer and thicker by affecting the hair growth cycle. However, it can cause side effects like redness, itching, or darkening of the eyelid skin and iris, so it's important to use it carefully.
Review score
Safety, usefulness, and evidence
Potentially useful with some tradeoffs
The evidence base is useful, but some claims depend heavily on the formula.
Main practical flags: irritation is moderate; clogging risk is low.
- Source
- synthetic
- Evidence
- moderate
- Irritation
- moderate
- Clogging risk
- low
Quick decision guide
Useful, but context matters
Dechloro Cyclopropylcloprostenolamide can be useful, but watch for some irritation potential.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Dechloro Cyclopropylcloprostenolamide.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
moderateCan bother some users, especially with frequent use, damaged skin, or strong companion ingredients.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
moderateThere is useful support, but formula details and claim strength still matter.
What it is
A synthetic analog of prostaglandin, a hormone-like compound that naturally occurs in the body. It is specifically designed to be used in cosmetic eyelash products to promote the appearance of longer, fuller lashes.
How it works
It is believed to extend the growth phase (anagen phase) of the eyelash hair cycle, allowing lashes to grow longer and stay in place longer before shedding. It may also increase the number of hairs that are actively growing.
Pros
Visible lash lengthening
Many users report noticeable improvement in lash length and fullness within a few weeks of consistent use.
Non-invasive alternative
Offers a cosmetic option for enhancing lashes without the need for extensions or mascara.
Cons and cautions
Potential for eye irritation
Common side effects include stinging, redness, and itching around the eyes, which can be uncomfortable.
Risk of pigment changes
May cause darkening of the eyelid skin or even the iris (the colored part of the eye), which can be permanent.
Best for
- People looking to enhance the appearance of their natural eyelashes
- Those who have tried other lash serums with limited success
Use caution if
- Individuals with sensitive eyes or a history of eye conditions like glaucoma
- Pregnant or breastfeeding women (due to lack of safety data)
Usage tips
Safety summary
Generally considered safe for topical cosmetic use at low concentrations, but it carries a moderate risk of eye irritation and pigment changes. Long-term safety data is limited, so caution is advised, especially for those with sensitive eyes.
Research notes
Evidence is primarily based on its similarity to prescription prostaglandin analogs, which have been studied for glaucoma and lash growth. Direct studies on this specific ingredient are limited, but user reports suggest effectiveness with potential side effects.
Common label clues
- Typical concentration
- Very low, typically 0.01% or less
- Regulatory status
- Not specifically approved by the FDA for cosmetic use; it is regulated as a cosmetic ingredient and must be safe for its intended use.
- Common uses
- Eyelash serums
- Environmental note
- As a synthetic compound, its environmental impact is not well studied, but it is used in very small quantities.
Good to know
- This ingredient is similar to prescription lash growth products but is sold in lower concentrations in cosmetics.
- Always patch test a small area behind your ear before applying near the eyes.
Common questions
What is Dechloro Cyclopropylcloprostenolamide in beauty products?
This is a lab-made ingredient similar to a natural substance called prostaglandin. In eyelash serums, it's thought to encourage lashes to grow longer and thicker by affecting the hair growth cycle. However, it can cause side effects like redness, itching, or darkening of the eyelid skin and iris, so it's important to use it carefully.
What does Dechloro Cyclopropylcloprostenolamide do in a beauty product?
It is believed to extend the growth phase (anagen phase) of the eyelash hair cycle, allowing lashes to grow longer and stay in place longer before shedding. It may also increase the number of hairs that are actively growing.
Is Dechloro Cyclopropylcloprostenolamide safe for most people?
Generally considered safe for topical cosmetic use at low concentrations, but it carries a moderate risk of eye irritation and pigment changes. Long-term safety data is limited, so caution is advised, especially for those with sensitive eyes.
Who should be careful with Dechloro Cyclopropylcloprostenolamide?
Individuals with sensitive eyes or a history of eye conditions like glaucoma Pregnant or breastfeeding women (due to lack of safety data)
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.