Ingredient review
Botrytis Cinerea Ferment Lysate Filtrate
INCI: Botrytis Cinerea Ferment Lysate Filtrate
A gentle, antioxidant-rich ferment that may help protect skin from environmental stress, but research is still early.
In plain English
This ingredient is made by fermenting a specific fungus (Botrytis cinerea, also known as noble rot) and then filtering it to create a liquid rich in beneficial compounds. In skincare, it's used to help protect skin from damage caused by pollution and UV rays, thanks to its antioxidant activity. It's generally very gentle and unlikely to clog pores or cause irritation.
Review score
Safety, usefulness, and evidence
Potentially useful with some tradeoffs
The evidence base is still emerging, so marketing claims deserve extra caution.
Risk flags are low for most users, though the finished product can still irritate.
- Source
- biotech
- Evidence
- emerging
- Irritation
- low
- Clogging risk
- low
Quick decision guide
Useful, but context matters
Botrytis Cinerea Ferment Lysate Filtrate is generally a lower-concern ingredient when the full formula suits your skin.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Botrytis Cinerea Ferment Lysate Filtrate.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
lowLess likely to sting, burn, or bother most users, though sensitive skin can still react.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
emergingThe ingredient may be promising, but claims should be treated more cautiously.
What it is
A fermented filtrate derived from the fungus Botrytis cinerea, which is the same fungus used to produce noble rot wines like Sauternes. The fermentation process breaks down the fungus, releasing peptides, polysaccharides, and other bioactive molecules.
How it works
It works primarily as an antioxidant, neutralizing free radicals that can damage skin cells and accelerate aging. It also has skin-conditioning properties, helping to maintain the skin's moisture barrier and soothe minor irritation.
Pros
Gentle antioxidant
Provides antioxidant benefits without the irritation that some stronger antioxidants (like pure vitamin C) can cause, making it suitable for sensitive skin.
Soothes skin
May help calm redness and minor irritation, offering a dual benefit of protection and comfort.
Cons and cautions
Limited research
Most evidence comes from lab studies, not large human trials, so the real-world benefits are not yet fully proven.
Higher cost
The fermentation and filtration process makes this ingredient more expensive than simpler antioxidants, which can increase the product price.
Best for
- People with normal to dry skin looking for antioxidant protection
- Those with sensitive skin who want a gentle, non-irritating antioxidant
Use caution if
- Individuals with a known allergy to molds or fungi (rare)
Usage tips
Safety summary
Considered safe for topical use with a very low risk of irritation or allergic reaction. Patch testing is recommended for those with known mold allergies.
Research notes
Preliminary in vitro studies show antioxidant and anti-inflammatory activity, but more clinical research on human skin is needed to confirm long-term benefits.
Common label clues
- Typical concentration
- 0.5% to 5% in leave-on products
- Regulatory status
- Generally recognized as safe for cosmetic use in the US and EU, with no specific restrictions.
- Common uses
- Serums, Moisturizers, Anti-aging creams
- Environmental note
- The fermentation process is relatively sustainable, using renewable resources and producing minimal waste compared to chemical synthesis.
Good to know
- Botrytis cinerea is the same fungus used to make noble rot wines, but the skincare version is produced in a controlled lab setting.
- This ingredient is often found in luxury or high-performance skincare lines due to its sophisticated production process.
Common questions
What is Botrytis Cinerea Ferment Lysate Filtrate in beauty products?
This ingredient is made by fermenting a specific fungus (Botrytis cinerea, also known as noble rot) and then filtering it to create a liquid rich in beneficial compounds. In skincare, it's used to help protect skin from damage caused by pollution and UV rays, thanks to its antioxidant activity. It's generally very gentle and unlikely to clog pores or cause irritation.
What does Botrytis Cinerea Ferment Lysate Filtrate do in a beauty product?
It works primarily as an antioxidant, neutralizing free radicals that can damage skin cells and accelerate aging. It also has skin-conditioning properties, helping to maintain the skin's moisture barrier and soothe minor irritation.
Is Botrytis Cinerea Ferment Lysate Filtrate safe for most people?
Considered safe for topical use with a very low risk of irritation or allergic reaction. Patch testing is recommended for those with known mold allergies.
Who should be careful with Botrytis Cinerea Ferment Lysate Filtrate?
Individuals with a known allergy to molds or fungi (rare)
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.