Ingredient review
Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide
INCI: BENZYLCARBAMATO CINNAMIDOISOPENTYL DIPEPTIDE-38 AMIDE
A synthetic peptide that may help soften expression lines and improve skin firmness, but evidence is mostly from ingredient supplier studies.
In plain English
This ingredient is a lab-made peptide, which is a short chain of amino acids (the building blocks of proteins). It is designed to mimic natural signaling molecules in the skin, potentially telling skin cells to produce more collagen and relax muscle contractions. In simple terms, it aims to make fine lines and wrinkles less noticeable over time, similar to how some anti-aging peptides work.
Quick decision guide
Useful, but context matters
Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide is generally a lower-concern ingredient when the full formula suits your skin.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
lowLess likely to sting, burn, or bother most users, though sensitive skin can still react.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
moderateThere is useful support, but formula details and claim strength still matter.
What it is
A synthetic dipeptide (two amino acids linked together) modified with a benzylcarbamato group and a cinnamidoisopentyl group to improve stability and skin penetration. It is a relatively new cosmetic ingredient developed for anti-aging formulations.
How it works
It is believed to work by mimicking the action of natural neuropeptides that can temporarily relax facial muscles, reducing the appearance of expression lines. Additionally, it may stimulate collagen synthesis by signaling fibroblasts (skin cells that produce collagen) to increase production, leading to firmer, more resilient skin over time.
Pros
Targets expression lines
Designed to relax facial muscles, which may soften crow's feet and forehead lines without the need for injectables.
Low irritation profile
Typically well-tolerated even on sensitive skin, making it a good option for those who cannot use stronger anti-aging ingredients.
Cons and cautions
Limited independent evidence
Most studies are funded by ingredient suppliers, so the real-world effectiveness may be less dramatic than claimed.
Results take time
Peptides generally require consistent use over several weeks to months before visible improvements appear, which may test patience.
Best for
- Adults looking to soften expression lines around the eyes and forehead
- Those seeking a gentle anti-aging ingredient without strong actives like retinol
Use caution if
- Individuals with known allergies to synthetic peptides (rare)
Usage tips
Safety summary
Considered safe for cosmetic use at typical concentrations. Rare reports of mild irritation or allergic reactions. No known systemic toxicity when used topically.
Research notes
Evidence is primarily from in vitro studies and manufacturer-sponsored clinical trials showing improvements in wrinkle depth and skin firmness. Independent peer-reviewed studies are limited, so the evidence level is moderate.
Common label clues
- Typical concentration
- 0.1% to 1%
- Regulatory status
- Approved for cosmetic use in the EU, US, and other major markets. Not classified as a drug ingredient.
- Common uses
- Anti-aging serums, Eye creams, Facial moisturizers
- Environmental note
- Synthetic peptides are produced in laboratories, which reduces the need for natural resource extraction, but their environmental impact depends on manufacturing practices.
Good to know
- This peptide is often included in high-end anti-aging serums and eye creams.
- It is compatible with most other skincare ingredients, including vitamin C and retinol, but always patch test when combining new products.
Common questions
What is Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide in beauty products?
This ingredient is a lab-made peptide, which is a short chain of amino acids (the building blocks of proteins). It is designed to mimic natural signaling molecules in the skin, potentially telling skin cells to produce more collagen and relax muscle contractions. In simple terms, it aims to make fine lines and wrinkles less noticeable over time, similar to how some anti-aging peptides work.
What does Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide do in a beauty product?
It is believed to work by mimicking the action of natural neuropeptides that can temporarily relax facial muscles, reducing the appearance of expression lines. Additionally, it may stimulate collagen synthesis by signaling fibroblasts (skin cells that produce collagen) to increase production, leading to firmer, more resilient skin over time.
Is Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide safe for most people?
Considered safe for cosmetic use at typical concentrations. Rare reports of mild irritation or allergic reactions. No known systemic toxicity when used topically.
Who should be careful with Benzylcarbamato Cinnamidoisopentyl Dipeptide-38 Amide?
Individuals with known allergies to synthetic peptides (rare)
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.