Ingredient review
Bacillus Licheniformis Keratinase
INCI: Bacillus Licheniformis Keratinase
A gentle enzymatic exfoliant that dissolves dead skin cells without harsh scrubbing, but may irritate sensitive skin if overused.
In plain English
This is an enzyme made from a type of bacteria that eats up the protein (keratin) that holds dead skin cells together. When applied to your face, it gently loosens and removes those dead cells, leaving your skin smoother and brighter. Unlike gritty scrubs, it works chemically, so you don't have to rub hard.
Review score
Safety, usefulness, and evidence
Potentially useful with some tradeoffs
The evidence base is useful, but some claims depend heavily on the formula.
Main practical flags: irritation is moderate; clogging risk is low.
- Source
- biotech
- Evidence
- moderate
- Irritation
- moderate
- Clogging risk
- low
Quick decision guide
Useful, but context matters
Bacillus Licheniformis Keratinase can be useful, but watch for some irritation potential.
Plain-English read
Treat this as a practical screening step before you compare products that contain this ingredient.
- Step 1Start with the score, then check the irritation and clogging risk before judging Bacillus Licheniformis Keratinase.
- Step 2Use the "Best for" and "Use caution if" sections to match the ingredient to your skin, not just to a marketing claim.
- Step 3If a product stings, breaks you out, or worsens irritation, judge the finished formula and stop using it even if the ingredient scores well.
Score terms in plain English
Irritation risk
moderateCan bother some users, especially with frequent use, damaged skin, or strong companion ingredients.
Clogging risk
lowLess likely to feel heavy or contribute to clogged pores for most skin types.
Evidence level
moderateThere is useful support, but formula details and claim strength still matter.
What it is
A purified enzyme produced by the bacterium Bacillus licheniformis, specifically designed to break down keratin, the tough protein that makes up the outer layer of skin.
How it works
When applied to the skin, the keratinase enzyme cleaves the peptide bonds in keratin, dissolving the 'glue' that binds dead skin cells. This allows them to slough off naturally, revealing fresher skin underneath. It works best in a slightly acidic to neutral pH environment.
Pros
Gentle chemical exfoliation
Dissolves dead skin cells without the need for abrasive particles, reducing the risk of micro-tears.
Improves skin texture
Regular use can lead to visibly smoother and more even-toned skin, especially on rough patches.
Cons and cautions
Potential irritation
Overuse or prolonged contact can cause redness, stinging, or peeling, especially on sensitive skin.
pH sensitivity
The enzyme's activity is highly dependent on the product's pH; if the formula is too alkaline or acidic, it may not work effectively.
Best for
- People with dull, rough skin looking for gentle exfoliation
- Those who prefer enzyme exfoliants over acids or scrubs
Use caution if
- Individuals with active eczema, rosacea, or open wounds
Usage tips
Safety summary
Considered safe for most skin types when used as directed. Avoid contact with eyes and do not use on broken or inflamed skin. Patch test recommended for first-time users.
Research notes
Studies show keratinase effectively degrades keratin and improves skin smoothness. However, most research is from ingredient suppliers, and independent clinical data is limited.
Common label clues
- Typical concentration
- 0.1% to 1%
- Regulatory status
- Generally recognized as safe for cosmetic use in the EU and US when formulated within recommended concentrations.
- Common uses
- Exfoliating serums, Peeling treatments, Anti-aging products
- Environmental note
- Produced via fermentation, which is a relatively low-impact biotech process, though the specific strain and production methods vary by supplier.
Good to know
- This ingredient is often listed as 'Bacillus Licheniformis Ferment' or simply 'Keratinase' on labels.
- Enzyme exfoliants like this are generally considered milder than AHAs or BHAs.
Common questions
What is Bacillus Licheniformis Keratinase in beauty products?
This is an enzyme made from a type of bacteria that eats up the protein (keratin) that holds dead skin cells together. When applied to your face, it gently loosens and removes those dead cells, leaving your skin smoother and brighter. Unlike gritty scrubs, it works chemically, so you don't have to rub hard.
What does Bacillus Licheniformis Keratinase do in a beauty product?
When applied to the skin, the keratinase enzyme cleaves the peptide bonds in keratin, dissolving the 'glue' that binds dead skin cells. This allows them to slough off naturally, revealing fresher skin underneath. It works best in a slightly acidic to neutral pH environment.
Is Bacillus Licheniformis Keratinase safe for most people?
Considered safe for most skin types when used as directed. Avoid contact with eyes and do not use on broken or inflamed skin. Patch test recommended for first-time users.
Who should be careful with Bacillus Licheniformis Keratinase?
Individuals with active eczema, rosacea, or open wounds
Research sources
Ingredient reviews are educational and are not medical advice. Patch test new products and ask a licensed clinician about persistent irritation, allergies, pregnancy-specific questions, or diagnosed skin conditions.